WordNet

a message whose ingenuity or verbal skill or incongruity has the power to evoke laughter (同)humor, humour, witticism, wittiness
a pattern of symptoms indicative of some disease
a complex of concurrent things; "every word has a syndrome of meanings"
swelling from excessive accumulation of watery fluid in cells, tissues, or serous cavities (同)oedema, hydrops, dropsy
having similarity in size, shape, and relative position of corresponding parts (同)symmetric

PrepTutorEJDIC

《随伴・協調》…『と』,と共に,といっしょに / 《所有・所持》…『を持っている』,がある,の付いた / 《道具・手段》…『で』,を使って / 《財料・供給物》…『で』,を与えて / …を支持して,に賛成して / …『に反対(敵対)して』,を相手として / …『と同時に』,と同様に / …『に比べて』,に比例して / 《様態》《名詞を伴い副詞句として》『…で』,を示して,をもって / 《付帯状競》…『して』,しながら / 《譲歩》…がありながら,にもかかわらず / 『…が原因で』,のために,…で / …に任せて,のもとにあずけて,のところに / …に関して,について / …から離れて / 《連結・混合》…と / 《副詞と共に命令文で》
知る(know)
〈U〉『機知』,機転,ウィット / 〈C〉『機知に富む人』,機転のきく人 / 《複数形で;単数扱い》『理解(表現)力』,知性 / 《複数形で》(物事を見抜いたりもくろんだりする)才覚,才知 / 《複数形で;単数扱い》正気
(疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態
浮腫(ふしゅ),水腫

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1. リウマチ性多発筋痛の臨床症状および診断 clinical manifestations and diagnosis of polymyalgia rheumatica
2. 悪性腫瘍およびリウマチ性疾患 malignancy and rheumatic disorders
3. 再発性多発性軟骨炎の臨床症状 clinical manifestations of relapsing polychondritis
4. 全身性疾患のミオパシー myopathies of systemic disease
5. 巨細胞（側頭）動脈炎の臨床症状 clinical manifestations of giant cell temporal arteritis

Syndrome of remitting seronegative symmetrical synovitis with pitting edema: A case series.

Varshney AN1, Singh NK.
Journal of postgraduate medicine.J Postgrad Med.2015 Jan-Mar;61(1):38-41. doi: 10.4103/0022-3859.147038.
Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE) is a rare clinical entity that is easily missed due to lack of knowledge. It was formerly considered as a subset of rheumatoid arthritis (RA), but is now regarded as a distinct disease/syndrome. The diagnosis of RS3PE is not eas
PMID 25511217

Synovitis with pitting edema as the presenting manifestation of systemic lupus erythematosus.

Hegazi MO1, Saleh F2, Al Rashidi A3, Yaktien MM4.
Lupus.Lupus.2014 Sep;23(10):1069-72. doi: 10.1177/0961203314533601. Epub 2014 Apr 30.
Rheumatologists are increasingly aware of the entity synovitis with pitting edema. The remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome has been reported with an array of conditions that include polymyalgia rheumatica, rheumatoid arthritis, Sjögren's syndrome and pso
PMID 24786784

Novel Development of Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE) Syndrome due to Insulin Therapy.

Mainali NR1, Schmidt TR2, Alweis R3, George DL3.
The American journal of case reports.Am J Case Rep.2014 Mar 21;15:119-22. doi: 10.12659/AJCR.890318. eCollection 2014.
PATIENT: Male, 67 FINAL DIAGNOSIS: Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome Symptoms: Bilateral wrist swelling Medication: - Clinical Procedure: - Specialty: Rheumatology.OBJECTIVE: Unusual or unexpected effect of treatment.BACKGROUND: Remitting seronegative s
PMID 24696753

Myelodysplastic Syndrome Precedes the Onset of Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE) Syndrome

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The Tohoku Journal of Experimental Medicine 235(1), 47-52, 2015
… Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome is characterized by symmetrical synovitis predominantly involving the wrists, and is associated with marked pitting edema of the dorsum of the hands. …
NAID 130004822427

小畑ダニエル,藤井洋泉,香曽我部義則,梶木秀樹
日本ペインクリニック学会誌 21(2), 119-123, 2014
… 脊椎疾患による上肢・下肢痛の治療中に，突然の多発関節痛と浮腫が発現し，臨床症状と血液検査よりRS3PE（remitting seronegative symmetrical synovitis with pitting edema）症候群と診断した2症例を経験した．2症例ともに男性で，少量のステロイドの内服により短期間で関節痛と浮腫が消失した．ペインクリニッ …
NAID 130004848633

Three Cases of Vasospastic Angina that Developed Following the Initiation of Corticosteroid Therapy

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Internal Medicine 53(3), 221-225, 2014
… Three patients diagnosed as having remitting seronegative symmetrical synovitis with pitting edema syndrome, pemphigus erythematosus and idiopathic interstitial pneumonia were treated with oral prednisolone. …
NAID 130003392633