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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/06/02 23:02:56」(JST)

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Serostatus refers to the presence or absence of a serological marker in the blood. The presence of detectable levels of a specific marker within the serum is considered seropositivity, while the absence of such levels is considered seronegativity.

HIV/AIDS

The term serostatus is commonly used in HIV/AIDS prevention efforts. In recent years, social advocacy has emphasized the importance of learning one's HIV/AIDS serostatus in an effort to curtail the spread of the disease.^[1]

Autoimmune disease

Researchers have investigated the effects of autoantibody serostatus on autoimmune disease presentation.^[2]^[3]^[4] Study of seronegative patient populations has led to the identification of additional autoantibodies that could potentially help with diagnosis.^[5]^[6]

References

^ Janssen RS, Holtgrave DR, Valdiserri RO, et al. (July 2001). "The Serostatus Approach to Fighting the HIV Epidemic: prevention strategies for infected individuals". American Journal of Public Health (American Public Health Association) 91 (7): 1019–1024. doi:10.2105/AJPH.91.7.1019. ISSN 1541-0048. PMC 1446705. PMID 11441723.
^ Jarius S, Ruprecht K, Wildemann B, et al. (January 2012). "Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients". Journal of Neuroinflammation (BioMed Central) 9 (1): 14. doi:10.1186/1742-2094-9-14. PMC 3283476. PMID 22260418.
^ Ajeganova S, Huizinga TW (November 2014). "Rheumatoid arthritis: Seronegative and seropositive RA: alike but different?". Nature Reviews Rheumatology (Nature Publishing Group) 11 (1): 8–9. doi:10.1038/nrrheum.2014.194. ISSN 1759-4804. PMID 25403158.
^ Balasubramanian G, Sugumar A, Smyrk TC, et al. (2012). "Demystifying seronegative autoimmune pancreatitis". Pancreatology (Elsevier) 12 (4): 289–294. doi:10.1016/j.pan.2012.05.003. PMID 22898628.
^ Somers K, Geusens P, Elewaut D, et al. (February 2011). "Novel autoantibody markers for early and seronegative rheumatoid arthritis". Journal of Autoimmunity (Elsevier) 36 (1): 33–46. doi:10.1016/j.jaut.2010.10.003. ISSN 0896-8411. PMID 21071175.
^ Pevzner A, Schoser B, Peters K, et al. (August 2011). "Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis" (PDF). Journal of Neurology (Springer-Verlag) 259 (3): 427–435. doi:10.1007/s00415-011-6194-7. ISSN 1432-1459. PMID 21814823.

UpToDate Contents

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1. 成人における強直性脊椎炎の診断および鑑別診断 diagnosis and differential diagnosis of ankylosing spondylitis in adults
2. 成人における多関節痛の評価 evaluation of the adult with polyarticular pain
3. 成人における強直性脊椎炎の臨床症状 clinical manifestations of ankylosing spondylitis in adults
4. 関節リウマチの診断および鑑別診断 diagnosis and differential diagnosis of rheumatoid arthritis
5. 成人における単関節痛の評価 evaluation of the adult with monoarticular pain

English Journal

Investigation of anti-neuronal antibodies in status epilepticus of unknown etiology: a prospective study.

Atmaca MM1, Tuzun E2, Erdag E2, Bebek N3, Baykan B3, Gurses C3.
Acta neurologica Belgica.Acta Neurol Belg.2017 Dec;117(4):841-848. doi: 10.1007/s13760-017-0796-5. Epub 2017 May 25.
PMID 28547540

Autoimmune acute liver failure and seronegative autoimmune liver disease in children: Are they different from classical disease?

Jain V1, Srivastava A, Yachha SK, Kumari N, Kathuria R, Sarma MS, Poddar U, Krishnani N.
European journal of gastroenterology & hepatology.Eur J Gastroenterol Hepatol.2017 Dec;29(12):1408-1415. doi: 10.1097/MEG.0000000000000975.
PMID 28914695

SERPING1 mRNA overexpression in monocytes from HIV+ patients.

Sanfilippo C1, Cambria D1, Longo A1, Palumbo M1, Avola R1, Pinzone M2, Nunnari G3, Condorelli F4, Musumeci G5, Imbesi R5, Castogiovanni P5, Malaguarnera L1, Di Rosa M6,7.
Inflammation research : official journal of the European Histamine Research Society ... [et al.].Inflamm Res.2017 Dec;66(12):1107-1116. doi: 10.1007/s00011-017-1091-x. Epub 2017 Sep 9.
PMID 28889214