WordNet

aerate (sewage) so as to favor the growth of organisms that decompose organic matter (同)aerate
make (substances) radioactive
make active or more active; "activate an old file"
make more adsorptive; "activate a metal"
rendered active; e.g. rendered radioactive or luminescent or photosensitive or conductive
(of e.g. a molecule) made reactive or more reactive (同)excited
(military) set up and placed on active assignment; "a newly activated unit"
(of sewage) treated with aeration and bacteria to aid decomposition
a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

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1. 複合免疫不全 combined immunodeficiencies
2. インスリン受容体の構造および機能 structure and function of the insulin receptor
3. T細胞受容体シグナル伝達 t cell receptor signaling
4. 肥満細胞由来のメディエーター mast cell derived mediators
5. 免疫不全症を引き起こすCD3／T細胞受容体複合体疾患 cd3 t cell receptor complex disorders causing immunodeficiency

Blocking PAR2 attenuates oxaliplatin-induced neuropathic pain via TRPV1 and releases of substance P and CGRP in superficial dorsal horn of spinal cord.

Chen K1, Zhang ZF1, Liao MF1, Yao WL1, Wang J1, Wang XR2.
Journal of the neurological sciences.J Neurol Sci.2015 May 15;352(1-2):62-7. doi: 10.1016/j.jns.2015.03.029. Epub 2015 Mar 25.
Oxaliplatin (OXL) is a third-generation chemotherapeutic agent commonly used to treat metastatic digestive tumors; however, neuropathic pain is one of the main limiting complications of OXL. The purpose of this study was to examine the underlying mechanisms by which neuropathic pain is induced by OX
PMID 25829079

Mechanisms Underlying the Scratching Behavior Induced by the Activation of Proteinase Activated Receptor-4 (PAR-4) in Mice.

Patricio ES1, Costa R2, Figueiredo CP2, Gers-Barlag K3, Bicca MA1, Manjavachi MN1, Segat GC1, Gentry C3, Luiz AP1, Fernandes ES4, Cunha TM5, Bevan S3, Calixto JB1.
The Journal of investigative dermatology.J Invest Dermatol.2015 May 8. doi: 10.1038/jid.2015.183. [Epub ahead of print]
A role for proteinase-activated receptor-4 (PAR-4) was recently suggested in itch sensation. Here, we investigated the mechanisms underlying the pruriceptive actions of the selective PAR-4 agonist AYPGKF-NH2 (AYP) in mice. Dorsal intradermal (i.d.) administration of AYP elicited intense scratching b
PMID 25955385

Regulation of Neutrophilic Inflammation by Proteinase-Activated Receptor 1 during Bacterial Pulmonary Infection.

José RJ1, Williams AE1, Mercer PF1, Sulikowski MG1, Brown JS1, Chambers RC2.
Journal of immunology (Baltimore, Md. : 1950).J Immunol.2015 May 6. pii: 1500124. [Epub ahead of print]
Neutrophils are key effector cells of the innate immune response to pathogenic bacteria, but excessive neutrophilic inflammation can be associated with bystander tissue damage. The mechanisms responsible for neutrophil recruitment to the lungs during bacterial pneumonia are poorly defined. In this s
PMID 25948816

Subepithelial trypsin induces enteric nerve-mediated anion secretion by activating proteinase-activated receptor 1 in the mouse cecum

Yamashita Toru,Abe Koji
Acta Medica Okayama 65(4), 219-223, 2011-08
… In the ischemic brain, free radicals and exogenous tPA itself can trigger MMP-9 activation through several signaling pathways containing LDL receptor-related protein (LRP) and proteinase-activated receptor 1 (PAR1). …
NAID 80021895203

リンク元	「PAR」「プロテアーゼ受容体」「プロテアーゼ活性化受容体」「protease-activated receptor」「プロテアーゼ活性化レセプター」
拡張検索	「proteinase-activated receptor 1」「proteinase-activated receptor 2」
関連記事	「activated」「activate」「proteinases」「proteinase」