WordNet
- aerate (sewage) so as to favor the growth of organisms that decompose organic matter (同)aerate
- make (substances) radioactive
- make active or more active; "activate an old file"
- make more adsorptive; "activate a metal"
- rendered active; e.g. rendered radioactive or luminescent or photosensitive or conductive
- (of e.g. a molecule) made reactive or more reactive (同)excited
- (military) set up and placed on active assignment; "a newly activated unit"
- (of sewage) treated with aeration and bacteria to aid decomposition
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
PrepTutorEJDIC
- …'を'活動的にする / …‘に'放射能を与える / 〈物質〉'を'活性化する
- =sense organ / 受信装置
UpToDate Contents
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- 1. 複合免疫不全 combined immunodeficiencies
- 2. インスリン受容体の構造および機能 structure and function of the insulin receptor
- 3. T細胞受容体シグナル伝達 t cell receptor signaling
- 4. 免疫不全症を引き起こすCD3／T細胞受容体複合体疾患 cd3 t cell receptor complex disorders causing immunodeficiency
- 5. 適応細胞性免疫応答 the adaptive cellular immune response
English Journal
- Proteasome inhibitors exacerbate interleukin-8 production induced by protease-activated receptor 2 in intestinal epithelial cells.
- Ghouzali I1, Azhar S1, Bôle-Feysot C1, Ducrotté P2, Déchelotte P3, Coëffier M4.
- Cytokine.Cytokine.2016 Oct;86:41-6. doi: 10.1016/j.cyto.2016.07.014. Epub 2016 Jul 25.
- Protease activated receptors (PARs) and the ubiquitin-proteasome system (UPS) regulate inflammatory response in intestinal cells. We aimed to elucidate putative connections between PARs and UPS pathways in intestinal epithelial cells. Caco-2 cells were treated by agonist peptides of PARs and/or IL-1
- PMID 27455449
- Protease-activated receptor-1 deficiency protects against streptozotocin-induced diabetic nephropathy in mice.
- Waasdorp M1, Duitman J1, Florquin S2, Spek CA1.
- Scientific reports.Sci Rep.2016 Sep 13;6:33030. doi: 10.1038/srep33030.
- Endogenously administered activated protein C ameliorates diabetic nephropathy (DN) in a protease-activated receptor-1 (PAR-1)-dependent manner, suggesting that PAR-1 activation limits the progression of DN. Activation of PAR-1 in fibroblast-like cells, however, induces proliferation and extracellul
- PMID 27618774
- Coagulation-driven hepatic fibrosis requires protease activated receptor-1 (PAR-1) in a mouse model of TCDD-elicited steatohepatitis.
- Nault R1, Fader KA1, Kopec AK2, Harkema JR3, Zacharewski TR1, Luyendyk JP4.
- Toxicological sciences : an official journal of the Society of Toxicology.Toxicol Sci.2016 Sep 9. pii: kfw175. [Epub ahead of print]
- Emerging evidence supports a role for environmental chemical exposure in the pathology of non-alcoholic fatty liver disease (NAFLD), a disease process tightly linked to increased activity of the blood coagulation cascade. Exposure of C57BL/6 mice to the persistent environmental contaminant 2,3,7,8-t
- PMID 27613713
Japanese Journal
- Prostaglandin E₂ Inhibits Proteinase-Activated Receptor 2-Signal Transduction through Regulation of Receptor Internalization
- KOMATSU Hiroyuki,ENJOUJI Shuhei,ITO Akihiro [他]
- The journal of veterinary medical science 75(3), 255-261, 2013-03
- NAID 40019635654
- Contribution of TRPA1 as a Downstream Signal of Proteinase-Activated Receptor-2 to Pancreatic Pain
- Terada Yuka,Fujimura Mayuko,Nishimura Sachiyo [他],Tsubota Maho,Sekiguchi Fumiko,Nishikawa Hiroyuki,Kawabata Atsufumi
- Journal of Pharmacological Sciences 123(3), 284-287, 2013
- … We examined if TRPA1, like TRPV1, contributes to pancreatic nociceptor excitation following proteinase-activated receptor-2 (PAR2) stimulation and to pancreatitis-related pain in mice. …
- NAID 130003382608
- Prostaglandin E2 Inhibits Proteinase-Activated Receptor 2-Signal Transduction through Regulation of Receptor Internalization
- KOMATSU Hiroyuki,ENJOUJI Shuhei,ITO Akihiro,OHAMA Takashi,SATO Koichi
- Journal of Veterinary Medical Science 75(3), 255-261, 2013
- … Proteinase-activated receptor (PAR) is expressed on various cells, and the PAR family consists of PAR1, PAR2, PAR3, and PAR4. … Individual PARs are activated during inflammatory conditions in which they regulate inflammatory responses in various diseases. …
- NAID 130001879641
Related Links
- 1. Pharmacol Rev. 2001 Jun;53(2):245-82. Proteinase-activated receptors. Macfarlane SR(1), Seatter MJ, Kanke T, Hunter GD, Plevin R. Author information: (1)Department of Physiology and Pharmacology, University of ...
- Protease activated receptor (PAR) の活性化機構： PARは、蛋白質分解酵素により、その細胞外領域の特定の部位が切断されると。新たに生じたN末端領域が受容体に作用し、活性化される。
Related Pictures
★リンクテーブル★
| リンク元 | 「PAR-1 receptor」「プロテアーゼ活性化受容体1」「PAR-1」「protease-activated receptor 1」 |
| 関連記事 | 「activated」「activate」「proteinases」「proteinase」 |
「PAR-1 receptor」
「プロテアーゼ活性化受容体1」
- 英
- protease-activated receptor 1、proteinase-activated receptor 1、PAR-1 receptor、PAR-1
- 関
- PAR-1受容体、プロテアーゼ活性化レセプター1、PAR-1レセプター
「PAR-1」
「protease-activated receptor 1」
「activated」
- adj.
- 活性化の、活性化型の、賦活化の
「activate」
- v.
- 活性化する、賦活化する、賦活する
「proteinases」
- 関
- See Proteases／proteinases
「proteinase」
- 日
- 関