proteinase-activated receptor 2

• プロテアーゼ活性化受容体2

関

PAR-2、PAR-2 receptor、protease-activated receptor 2

WordNet

1. aerate (sewage) so as to favor the growth of organisms that decompose organic matter (同)aerate
2. make (substances) radioactive
3. make active or more active; "activate an old file"
4. make more adsorptive; "activate a metal"
5. rendered active; e.g. rendered radioactive or luminescent or photosensitive or conductive
6. (of e.g. a molecule) made reactive or more reactive (同)excited
7. (military) set up and placed on active assignment; "a newly activated unit"
8. (of sewage) treated with aeration and bacteria to aid decomposition
9. a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

PrepTutorEJDIC

1. …'を'活動的にする / …‘に'放射能を与える / 〈物質〉'を'活性化する
2. =sense organ / 受信装置

UpToDate Contents

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• 1. インスリン受容体の構造および機能 structure and function of the insulin receptor
• 2. 複合免疫不全 combined immunodeficiencies
• 3. カルシウム感知性受容体障害：家族性低カルシウム尿性高カルシウム血症および
  常染色体優性低カルシウム血症 disorders of the calcium sensing receptor familial hypocalciuric hypercalcemia and autosomal dominant hypocalcemia
• 4. T細胞受容体シグナル伝達 t cell receptor signaling
• 5. β-2アドレナリン受容体機能不全および喘息の多型性 beta 2 adrenergic receptor dysfunction and polymorphism in asthma

English Journal

• The exercise-regulated myokine chitinase-3-like protein 1 stimulates human myocyte proliferation.

• Görgens SW1, Hjorth M2, Eckardt K1,2, Wichert S1, Norheim F2, Holen T2, Lee S2, Langleite T2, Birkeland KI2, Stadheim HK3, Kolnes KJ4, Tangen DS3, Kolnes AJ4, Jensen J3, Drevon CA2, Eckel J1,5.
• Acta physiologica (Oxford, England).Acta Physiol (Oxf).2016 Mar;216(3):330-45. doi: 10.1111/apha.12579. Epub 2015 Sep 8.
• AIM: Chitinase-3-like protein 1 (CHI3L1) is involved in tissue remodelling and inflammatory processes. Plasma levels are elevated in patients with insulin resistance and T2DM. We recently showed that CHI3L1 and its receptor protease-activated receptor 2 (PAR-2) are expressed in skeletal muscle. Acti
• PMID 26303257

• THE AUTOCRINE ROLE OF TRYPTASE IN PRESSURE OVERLOAD-INDUCED MAST CELL ACTIVATION, CHYMASE RELEASE AND CARDIAC FIBROSIS.

• Li J1, Jubair S1, Levick SP2, Janicki JS1.
• IJC metabolic & endocrine.IJC Metab Endocr.2016 Mar 1;10:16-23. Epub 2015 Nov 24.
• BACKGROUND: Cardiac mast cell (MC) proteases, chymase and tryptase, increase proliferation and collagen synthesis in cultured cardiac fibroblasts. However, the question as to why preventing individually the actions of either protease prevents fibrosis when both are released upon MC activation remain
• PMID 26722642

• Protease Activated Receptor-2 (PAR-2)-Mediated Nf-κB Activation Suppresses Inflammation-Associated Tumor Suppressor MicroRNAs in Oral Squamous Cell Carcinoma.

• Johnson JJ1, Miller DL2, Jiang R3, Liu Y1, Shi Z1, Tarwater L1, Williams R4, Balsara R5, Sauter ER6, Stack MS7.
• The Journal of biological chemistry.J Biol Chem.2016 Feb 2. pii: jbc.M115.692640. [Epub ahead of print]
• Oral cancer is the sixth most common cause of death from cancer with an estimated 400,000 deaths worldwide and a low (50%) 5-year survival rate. The most common form of oral cancer is oral squamous cell carcinoma (OSCC). OSCC is highly inflammatory and invasive and the degree of inflammation correla
• PMID 26839311

Japanese Journal

• Use of Nasopancreatic Drainage for Severe Post-endoscopic Retrograde Cholangiopancreatography Pancreatitis: A Case Series

• Kawaguchi Shinya,Kikuyama Masataka,Satoh Tatsunori,Terada Shuzo
• Internal Medicine 57(18), 2657-2662, 2018
• … Bacteria-induced protease-activated receptor-2 activation may be associated with PEP. …
• NAID 130007484372

• Use of Nasopancreatic Drainage for Severe Post-endoscopic Retrograde Cholangiopancreatography Pancreatitis: A Case Series

• Kawaguchi Shinya,Kikuyama Masataka,Satoh Tatsunori,Terada Shuzo
• Internal Medicine, 2018
• … Bacteria-induced protease-activated receptor-2 activation may be associated with PEP. …
• NAID 130006727983

• 腎ポドサイト障害進展におけるProteinase-activated receptor-1の関与

• 中野 大介,管 瑀,劉 文華,張 一凡,李 磊,人見 浩史,平野 勝也,西山 成
• 日本毒性学会学術年会 44.1(0), O-53, 2017
• … 本研究ではトロンビン受容体であるProteinase-activated receptor-1 (PAR1)のポドサイト障害進展における役割を検討した。 …
• NAID 130006581968

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★リンクテーブル★

リンク元	「プロテアーゼ活性化受容体2」「PAR-2 receptor」「protease-activated receptor 2」「PAR-2」
関連記事	「activated」「activate」「proteinases」「proteinase」

「プロテアーゼ活性化受容体2」

　　[★]

英

protease-activated receptor 2、proteinase-activated receptor 2、PAR-2 receptor、PAR-2

関

PAR-2受容体、PAR-2レセプター、プロテアーゼ活性化レセプター2、トリプシン受容体

「PAR-2 receptor」

　　[★]

• プロテアーゼ活性化受容体2、PAR-2受容体、PAR-2レセプター

関

PAR-2、protease-activated receptor 2、proteinase-activated receptor 2、trypsin receptor

「protease-activated receptor 2」

　　[★]

• プロテアーゼ活性化受容体2、プロテアーゼ活性化レセプター2

関

PAR-2、PAR-2 receptor、proteinase-activated receptor 2、trypsin receptor

「PAR-2」

　　[★]

• プロテアーゼ活性化受容体2

関

PAR-2 receptor、protease-activated receptor 2、proteinase-activated receptor 2

「activated」

　　[★]

• adj.

• 活性化の、活性化型の、賦活化の

関

activate、activated form、activation、turn on

　 　 　 　

「activate」

　　[★]

• v.

• 活性化する、賦活化する、賦活する

関

activated、activation、turn on

　 　 　 　 　

「proteinases」

　　[★]

関

See Proteases／proteinases

「proteinase」

　　[★]

日

関

同

proteinases