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Wang Y1, Zhao W1, Gao Q1, Fan L1, Qin Y1, Zhou H2, Li M3, Fang J4.
Cancer letters.Cancer Lett.2016 Dec 1;383(1):1-8. doi: 10.1016/j.canlet.2016.09.009. Epub 2016 Sep 28.
Nuclear factor (NF)-κB is a transcription factor that plays an important role in many biological functions. Regulation of NF-κB activity is complicated, and ubiquitination is essential for NF-κB activation. Hypoxia can activate NF-κB. However, the underlying mechanism remains unclear. pVHL is a
PMID 27693634

Hydroxylases regulate intestinal fibrosis through the suppression of ERK mediated TGF-β1 signaling.

Cabrero Manresa M1, Tambuwala MM2, Radhakrishnan P3, Harnoss JM3, Brown E4, Cavadas MA4, Keogh CE4, Cheong A4, Barrett KE5, Cummins EP4, Schneider M3, Taylor CT6.
American journal of physiology. Gastrointestinal and liver physiology.Am J Physiol Gastrointest Liver Physiol.2016 Oct 27:ajpgi.00229.2016. doi: 10.1152/ajpgi.00229.2016. [Epub ahead of print]
Fibrosis is a complication of chronic inflammatory disorders such as inflammatory bowel disease (IBD), a condition which has limited therapeutic options and often requires surgical intervention. Pharmacologic inhibition of oxygen-sensing prolyl hydroxylases (PHD), which confer oxygen-sensitivity upo
PMID 27789456

Ankyrin Repeat Proteins of Orf Virus Influence the Cellular Hypoxia Response Pathway.

Chen DY1, Fabrizio JA2, Wilkins SE2, Dave KA3, Gorman JJ3, Gleadle JM4, Fleming SB1, Peet DJ5, Mercer AA6.
Journal of virology.J Virol.2016 Oct 26. pii: JVI.01430-16. [Epub ahead of print]
Hypoxia inducible factor (HIF) is a transcriptional activator with a central role in regulating cellular responses to hypoxia. It is also emerging as a major target in viral manipulation of the cellular environment. Under normoxic conditions HIF is tightly suppressed by the activity of oxygen-depend
PMID 27795413

4) 腟壁と膀胱・尿道間の微小交感神経束を温存する合成メッシュ骨盤底再建手術(シンポジウム1:女性ヘルスケア「中高年に対する女性医学の展開」,第64回日本産科婦人科学会・学術講演会)

古山将康
日本産科婦人科學會雜誌 64(10), 2203-2213, 2012-10-01
… They locate more than 10mm away from a cluster of nerves found almost along the lateral edge of the vagina and stained with S100 and tyrosine hydroxylase (TH) antibody, originated from the cranial part of the pelvic plexus, and appeared to terminate at the urethral smooth muscles. … Synthetic proline soft mesh was inserted into behind of the vagina. …
NAID 110009518076

4Dp10 Microbial production of N-acetyl cis-4-hydroxy-L-proline by coexpression of the Rhizobium L-proline cis-4-hydroxylase and the yeast N-acetyltranferase Mpr1