pre-B cell receptor

• プレB細胞受容体、プレB細胞レセプター

WordNet

1. small room in which a monk or nun lives (同)cubicle
2. a device that delivers an electric current as the result of a chemical reaction (同)electric cell
3. a room where a prisoner is kept (同)jail cell, prison cell
4. (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
5. any small compartment; "the cells of a honeycomb"
6. a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
7. the 2nd letter of the Roman alphabet (同)b
8. the blood group whose red cells carry the B antigen (同)type_B, group B
9. a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

PrepTutorEJDIC

1. (刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
2. =sense organ / 受信装置

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• 1. びまん性大細胞型B細胞性リンパ腫の予後 prognosis of diffuse large b cell lymphoma
• 2. BおよびTリンパ球の正常な発生 normal b and t lymphocyte development
• 3. リンパ球増加症またはリンパ球減少症を有する患者へのアプローチ approach to the patient with lymphocytosis or lymphocytopenia
• 4. リウマチ性疾患における生物学的製剤の概要 overview of biologic agents in the rheumatic diseases
• 5. B細胞前リンパ球性白血病の臨床症状、病理学的特徴、および診断 clinical manifestations pathologic features and diagnosis of b cell prolymphocytic leukemia

English Journal

• Distinct processing of the pre-B cell receptor and the B cell receptor.

• Cohen S, Haimovich J, Hollander N.SourceDepartment of Clinical Microbiology and Immunology, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.
• Molecular immunology.Mol Immunol.2013 Jun;54(2):115-21. doi: 10.1016/j.molimm.2012.11.004. Epub 2012 Dec 23.
• It has been recently demonstrated that while oligosaccharide moieties of μ heavy chains in the B-cell receptor (BCR) are of the complex type as expected, those of the pre-BCR on the surface of pre-B cells contain oligosaccharide moieties of the high-mannose type only. This is unique, because high-m
• PMID 23267849

• Broad feedback inhibition of pre-B-cell receptor signaling components.

• Hauser J, Verma-Gaur J, Grundström T.SourceDepartment of Molecular Biology, Umeå University, SE-901 87 Umeå, Sweden.
• Molecular immunology.Mol Immunol.2013 Jan 11;54(3-4):247-253. doi: 10.1016/j.molimm.2012.12.002. [Epub ahead of print]
• During B lymphocyte development, first immunoglobulin heavy chain gene segments and then immunoglobulin light chain gene segments are rearranged to create antibody diversity. Early in the development, expression of a pre-B-cell receptor (pre-BCR) that has membrane-bound Ig heavy chain protein associ
• PMID 23318223

• Genome-wide identification of Ikaros targets elucidates its contribution to mouse B cell lineage specification and pre-B cell differentiation.

• Ferreirós Vidal I, Carroll T, Taylor B, Terry A, Liang Z, Bruno L, Dharmalingam G, Khadayate S, Cobb BS, Smale ST, Spivakov M, Srivastava P, Petretto E, Fisher AG, Merkenschlager M.SourceLymphocyte Development Group, MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, London, United Kingdom;
• Blood.Blood.2013 Jan 9. [Epub ahead of print]
• Ikaros family DNA binding proteins are critical regulators of B cell development. Because current knowledge of Ikaros targets in B cell progenitors is limited we have identified genes that are bound and regulated by Ikaros in pre-B cells. To elucidate the role of Ikaros in B cell lineage specificati
• PMID 23303821

Japanese Journal

• The skewed heavy-chain repertoire in peritoneal B-1 cells is predetermined by the selection via pre-B cell receptor during B cell ontogeny in the fetal liver

• YOSHIKAWA Soichiro,KAWANO Yohei,MINEGISHI Yoshiyuki,KARASUYAMA Hajime
• International immunology 21(1), 43-52, 2009-01-01
• NAID 10025383848

• PKCη directs induction of IRF-4 expression and Ig κ gene rearrangement in pre-BCR signaling pathway

• ODA Akihisa,ONO Tomohiro,YAMAMOTO Mutsumi,GOITSUKA Ryo,KITAMURA Daisuke
• International immunology 20(11), 1417-1426, 2008-11-01
• NAID 10024357764

• Pre-B細胞レセプターからのシグナル伝達 (特集 B細胞分化の分子機構)

• 大西 和夫
• 臨床免疫・アレルギー科 49(2), 121-127, 2008-02
• NAID 40015897581

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★リンクテーブル★

リンク元	「プレB細胞受容体」「プレB細胞レセプター」
関連記事	「B」「PRE」「p」「cell」

「プレB細胞受容体」

　　[★]

英

pre-B cell receptor

関

プレB細胞レセプター

「プレB細胞レセプター」

　　[★]

英

pre-B cell receptor

関

プレB細胞受容体

「B」

　　[★]

• 気管分岐部下緑
• 補体のalternative pathwayに関わる蛋白質

• Mg2+存在下でC3, B, Dが反応してC3bBbとなり、これがC3転換酵素(C3bBb)あるいはC5転換酵素(C3bBb3b)を形成する。これらはP(properdin)と結合して活性化し、それぞれC3、C5を活性化する

　 　

「PRE」

　　[★]

• プロゲスチン応答配列 progestin response element
• プロゲステロン応答配列 progesterone response element

「p」

　　[★]

• ピコ

10の-12乗

関

pico

「cell」

　　[★] 細胞