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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2019/04/11 20:21:08」(JST)

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Polyarthritis is any type of arthritis that involves 5 or more joints simultaneously. It is usually associated with autoimmune conditions and may be experienced at any age and is not sex specific.

Causes

Polyarthritis is most often caused by an auto-immune disorder such as rheumatoid arthritis, amyloidosis, psoriatic arthritis, and lupus erythematosus but can also be caused by infection with an alphavirus such as chikungunya virus and Ross River virus. This condition is termed alphavirus polyarthritis syndrome. Sindbis virus, which is endemic in Northern Europe, Africa, the Middle East, and Australia, is the most widely distributed of the alphaviruses causing polyarthritis, though infection is usually mild or asymptomatic.

Associated conditions

It may be associated with bilateral edema in lower limbs, pain and joint swelling. Sometimes there is previous history of inflammatory joint problems and bilateral edema of lower limbs.

Alphavirus Polyarthritis Syndrome has an incubation period of 3–21 days, depending on the specific virus, with either a gradual or sudden onset of fever, arthralgias, headache, and lymphadenitis and conjunctivitis in some forms. A maculopapular rash may present 4–8 days post symptom onset and may be accompanied by an increase in fever. Joint pains associated with this condition may recur for many months after initial illness for up to a year.

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1. 成人における多関節痛の評価 evaluation of the adult with polyarticular pain
2. 関節リウマチの診断および鑑別診断 diagnosis and differential diagnosis of rheumatoid arthritis
3. 多関節型若年性特発性関節炎：臨床症状および診断 polyarticular onset juvenile idiopathic arthritis clinical manifestations and diagnosis
4. 多関節型若年性特発性関節炎：管理 polyarticular onset juvenile idiopathic arthritis management
5. ウイルス性関節炎の病因および診断 pathogenesis and diagnosis of viral arthritis

English Journal

A visible light induced photoelectrochemical aptsensor constructed by aligned ZnO@CdTe core shell nanocable arrays/carboxylated g-C3N4 for the detection of Proprotein convertase subtilisin/kexin type 6 gene.

Pang X1, Pan J2, Gao P1, Wang Y1, Wang L1, Du B3, Wei Q1.
Biosensors & bioelectronics.Biosens Bioelectron.2015 Dec 15;74:49-58. doi: 10.1016/j.bios.2015.06.030. Epub 2015 Jun 20.
It was reported that Proprotein convertase subtilisin/kexin type 6 (PCSK6) can promote the progression of rheumatoid arthritis to a higher aggressive status. In this work, a novel visible light induced photoelectrochemical (PEC) platform was designed to detect PCSK6 gene. ZnO@CdTe nanocable arrays/c
PMID 26119758

Association between polymorphisms of interleukin 12 and rheumatoid arthritis associated biomarkers in a Chinese population.

Shen L1, Zhang H2, Zhou X2, Liu R3.
Cytokine.Cytokine.2015 Dec;76(2):363-7. doi: 10.1016/j.cyto.2015.09.007. Epub 2015 Sep 12.
INTRODUCTION: The aim of the present study was to examine the association between polymorphisms of interleukin 12 (IL-12) and rheumatoid arthritis (RA) associated biomarkers in a Chinese population.MATERIALS AND METHODS: We studied IL-12A rs2243115 T/G and IL-12B rs3212227 A/C polymorphisms in 615 R
PMID 26375522

The role of cytokines in the pathogenesis of rheumatoid arthritis - Practical and potential application of cytokines as biomarkers and targets of personalized therapy.

Brzustewicz E1, Bryl E2.
Cytokine.Cytokine.2015 Dec;76(2):527-36. doi: 10.1016/j.cyto.2015.08.260. Epub 2015 Aug 29.
Rheumatoid arthritis (RA), as a common chronic disease leading to severe disability, requires early diagnosis and introduction of proper treatment. Deregulation in the cytokine network plays an undoubtedly crucial role in the pathogenesis of RA. The understanding of the role of cytokines in RA can b
PMID 26321413

Japanese Journal

臨床研究・症例報告 A群溶血性レンサ球菌保菌者からの感染が原因と考えられた化膿性多発関節炎の乳児例

小児科臨床 69(2), 171-174, 2016-02
NAID 40020703383

Corticosteroid Therapy for a Patient with Relapsing Polychondritis Complicated by IgG4-Related Disease

The Tohoku Journal of Experimental Medicine 239(3), 223-230, 2016
NAID 130005163074

Synovial fluid matrix metalloproteinase-2 and -9 activities in dogs suffering from joint disorders

Journal of Veterinary Medical Science 78(6), 1051-1054, 2016
NAID 130005159665

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★リンクテーブル★

リンク元	「多発性関節炎」「多発関節炎」「polyarticular」
拡張検索	「polyarthritis rheumatica」「inflammatory polyarthritis」