点状角質融解症
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/06/18 10:33:51」(JST)
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| Pitted keratolysis |
| Classification and external resources |
| ICD-10 |
L08.8 (ILDS L08.850) |
| DiseasesDB |
31346 |
Pitted keratolysis (also known as "Keratolysis plantare sulcatum,"[1] "Keratoma plantare sulcatum,"[1] and "Ringed keratolysis"[1]) is a non-contagious[citation needed] skin infection that can be caused by wearing tight or restricting footwear and excessive sweating. The infection is characterized by craterlike pits on the surface of the feet and toes, particularly weight bearing areas. Treatment consists of the application of topical antibiotics. Pitted Keratolysis is caused by bacteria,[2] which thrive in these environments.[3]
The condition is fairly common, especially in military where wet shoes/boots are worn for extended period of time without removing/cleaning. Skin biopsy specimens are not usually utilized, as the diagnosis of pitted keratolysis is often made by visual examination and recognition of the characteristic odor. Wood lamp examination results are inconsistent.
Contents
- 1 Symptoms
- 2 Risk factors
- 3 History
- 4 Over the counter treatment
- 5 See also
- 6 References
Symptoms
The most obvious sign that a person is suffering from pitted keratolysis is its classic appearance. The circular and shallow pits are the calling card of pitted keratolysis. The pits often overlap in places to produce larger areas of erosion. Occasionally these legions present with a green or brown hue around and within the pits. These superficial erosions are found under the toes and on the soles of the feet, and especially at the pressure bearing points such as the heel. Both sides of the foot are usually equally effected. Pitted keratolysis is often linked to excessive sweating of the palms or soles (palmoplantar hyperhidrosis.) The bacterial digestion of the keratin results in a very foul odor, causing many of its suffers great anxiety, especially in social situations. Thankfully, irritation is generally minimal, though occasionally burning, itching, and soreness are experienced with pitted keratolysis. The appearance of this condition’s characteristic lesions is much more pronounced when the affected area is wet.
Risk factors
People of any age, race, or sex can fall victim to this disorder, though it is more commonly found in men. People who sweat or wash excessively tend to be prone to pitted keratolysis. The prolonged wearing of occlusive footwear, such as tight shoes or rubber boots, also makes one more susceptible. Not surprisingly, athletes and soldiers are extremely prone to this problem. Hot and humid weather is another factor for raising the risk. Those on immunosuppressive drug therapy or diabetes sufferers are also more likely to succumb to pitted keratolysis.
History
Pitted keratolysis was first named "Keratoma plantare sulcatum."[4]:268
It was first described in India but has worldwide distribution.[citation needed]
Over the counter treatment
Pitted keratolysis can be reduced and eventually stopped by regularly applying a liberal amount of antiperspirant body powder to the inside of the shoes and socks of the sufferer. Regular powder application will greatly reduce foot perspiration and keep the plantar surface of the foot dry therefore creating an environment hostile to the Corynebacterium.
See also
- List of cutaneous conditions
References
- ^ a b c Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
- ^ "Pitted keratolysis (Hyperhydrosis)". bunionbusters.com. Retrieved 22 March 2012.
- ^ "Without Proper Treatment, Skin Infections Can Sideline Your Season". American Academy of Dermatology. March 3, 2006. Retrieved February 2007.
- ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Fairly common, especially common in military. Saunders Elsevier. ISBN 0-7216-2921-0.
UpToDate Contents
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English Journal
- Skin conditions in figure skaters, ice-hockey players and speed skaters: part II - cold-induced, infectious and inflammatory dermatoses.
- Tlougan BE, Mancini AJ, Mandell JA, Cohen DE, Sanchez MR.SourceDepartment of Dermatology, Columbia University Medical Center, New York, NY 10032, USA. brook.tlougan@gmail.com
- Sports medicine (Auckland, N.Z.).Sports Med.2011 Nov 1;41(11):967-84. doi: 10.2165/11592190-000000000-00000.
- Participation in ice-skating sports, particularly figure skating, ice hockey and speed skating, has increased in recent years. Competitive athletes in these sports experience a range of dermatological injuries related to mechanical factors: exposure to cold temperatures, infectious agents and inflam
- PMID 21985216
- Skin Conditions in Figure Skaters, Ice-Hockey Players and Speed Skaters: Part II - Cold-Induced, Infectious and Inflammatory Dermatoses.
- Tlougan BE, Mancini AJ, Mandell JA, Cohen DE, Sanchez MR.Source1Department of Dermatology, Columbia University Medical Center, New York, NY, USA 2Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA 3Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA 4Division of Dermatology, Children's Memorial Hospital, Chicago, IL, USA 5Ronald O. Perelman Department of Dermatology, School of Medicine, New York University, New York, NY, USA 6Department of Dermatology, Bellevue Hospital Center, New York, NY, USA.
- Sports medicine (Auckland, N.Z.).Sports Med.2011 Sep 26. [Epub ahead of print]
- Participation in ice-skating sports, particularly figure skating, ice hockey and speed skating, has increased in recent years. Competitive athletes in these sports experience a range of dermatological injuries related to mechanical factors: exposure to cold temperatures, infectious agents and inflam
- PMID 21952223
- [Pitted keratolysis--how to treat?].
- Kamińska-Winciorek G, Spiewak R.SourceUniwersytet Jagielloński Collegium Medicum, Kraków, Zakład Dermatologii Doświadczalnej i Kosmetologii, Wydział Farmaceutyczny. dermatolog.pl@gmail.com
- Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego.Pol Merkur Lekarski.2011 Aug;31(182):127-9.
- Pitted keratolysis is a common and problematic skin condition affecting the feet caused by the keratolytic activity of Corynebacterium, Micrococcus, Dermatophilus. Skin lesions are characterized by crater-like pits of the epidermis accompanied by a burning sensation, itching, pain and malodor. The p
- PMID 21936353
Japanese Journal
- Pitted Keratolysis ; 臨床統計と気象変化について
- Pitted Keratolysis : clinical manifestations in 53 cases
Related Links
- 21 Sep 2012 ... Pitted keratolysis is a skin disorder characterized by crateriform pitting that primarily affects the pressure-bearing aspects of the plantar surface of the feet and, occasionally, the palms of the hand as collarettes of scale.
- 29 Jun 2011 ... Pitted keratolysis. Authoritative facts about the skin from the New Zealand Dermatological Society.
★リンクテーブル★
[★]
- 英
- pitted keratolysis
- 関
- 角質融解症
概念
病原体
corynebacteria, Dermatophilus congolensis, Kytococcus sedentarius, actinomyces, streptomyces
病因
- 特定の細菌感染による。
- 蜂巣状(horny cell, stratum corneum)は細菌が分泌するプロテアーゼにより表皮が融解されて起こる。
- 悪臭は細菌が分泌するイオウ化合物による。
症状
診断
- 視診で明らか
- 病原体同定のためにスワブスティックで培養検査を出すことがある。
- 真菌感染を除外するためには、表皮を採取することもある。
- 診断のためにパンチアウト皮膚生検し、病理組織学的に診断することがある。
鑑別診断
参考
- http://www.huidziekten.nl/zakboek/dermatosen/ptxt/PittedKeratolysis.htm
- http://www.dermnetnz.org/common/image.php?path=/pathology/img/e/pitted-keratolysis-figure-1.jpg
- http://en.wikipedia.org/wiki/Pitted_keratolysis
<youtube>http://www.youtube.com/watch?v=OMCU26CGkQg</youtube>
[★]
- 関
- keratolytic
