WordNet
- stated explicitly or in detail; "needed a specific amount"
- a medicine that has a mitigating effect on a specific disease; "quinine is a specific for malaria"
- (sometimes followed by `to'
- being or affecting a disease produced by a particular microorganism or condition; used also of stains or dyes used in making microscope slides; "quinine is highly specific for malaria"; "a specific remedy"; "a specific stain is one having a specific affinity for particular structural elements"
- relating to or distinguishing or constituting a taxonomic species; "specific characters"
- any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
PrepTutorEJDIC
- 《名詞の前にのみ用いて》『特定の』,一定の・『明確な』,明白な・(そのものに)『特有の』,独特の《+『to』+『名』》・〈C〉(…の)特効薬《+『for』+『名』》・《複数形で》明細,細部(details)
- 抗体,免疫体,抗毒素
UpToDate Contents
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- 1. 前立腺特異的抗原（PSA）の測定 measurement of prostate specific antigen
- 2. 免疫グロブリンの機能および臨床応用 function and clinical applications of immunoglobulins
- 3. 前立腺癌のスクリーニング screening for prostate cancer
- 4. Evaluation and treatment of antibody-mediated lung transplant rejection
- 5. 体液性免疫応答 the humoral immune response
English Journal
- AMP-activated protein kinase phosphorylates cardiac troponin I at Ser-150 to increase myofilament calcium sensitivity and blunt PKA-dependent function.
- Nixon BR, Thawornkaiwong A, Jin J, Brundage EA, Little SC, Davis JP, Solaro RJ, Biesiadecki BJ.SourceDepartment of Physiology and Cell Biology and The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio 43210, USA.
- The Journal of biological chemistry.J Biol Chem.2012 Jun 1;287(23):19136-47. Epub 2012 Apr 6.
- AMP-activated protein kinase (AMPK) is an energy-sensing enzyme central to the regulation of metabolic homeostasis. In the heart AMPK is activated during cardiac stress-induced ATP depletion and functions to stimulate metabolic pathways that restore the AMP/ATP balance. Recently it was demonstrated
- PMID 22493448
- Ionizing radiation regulates the expression of AMP-activated protein kinase (AMPK) in epithelial cancer cells: modulation of cellular signals regulating cell cycle and survival.
- Sanli T, Storozhuk Y, Linher-Melville K, Bristow RG, Laderout K, Viollet B, Wright J, Singh G, Tsakiridis T.SourceTranslational Radiation Biology Laboratory, Juravinski Cancer Center, Department of Pathology, McMaster University, Hamilton, Canada.
- Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.Radiother Oncol.2012 Mar;102(3):459-65. Epub 2012 Jan 5.
- PURPOSE: To analyze the (i) expression of AMPK in a variety of epithelial cancer cells, (ii) regulation of AMPK subunit expression by ionizing radiation (IR) and (iii) impact of AMPK on signaling pathways regulating cell cycle and survival.METHODS AND MATERIALS: Human lung, prostate, and breast norm
- PMID 22225791
Japanese Journal
- Dissociation of Bax from a Bcl-2/Bax Heterodimer Triggered by Phosphorylation of Serine 70 of Bcl-2.
- , , , , ,
- The Journal of Biochemistry 130(6), 741-748, 2001
- … The phosphorylation of serine 70 of Bcl-2 (pS70-Bc1-2) peaks 24 to 48 h after paclitaxel treatment and accelerates apoptosis. … Phosphorylation is effectively inhibited in the presence of actinomycin D or cycloheximide, which restore cell viability to the same level as control cells not expressing Bel-2. …
- NAID 130003534295
Related Links
- Until recently, the investigation of protein phosphorylation was limited to biochemical studies of enzyme activities in homogenized tissues. The availability of hundreds of phosphorylation state-specific antibodies (PSSAs) now makes ...
- 1. Nat Protoc. 2007;2(10):2574-81. Production of a site- and phosphorylation state-specific antibody. Goto H, Inagaki M. Division of Biochemistry, Aichi Cancer Center Research Institute, Nagoya, Aichi 464-8681, Japan. Protein ...
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★リンクテーブル★
| リンク元 | 「リン酸化特異抗体」「リン酸化部位特異的抗体」 |
| 関連記事 | 「specific」「phosphorylation」「specific antibody」 |
「リン酸化特異抗体」
「リン酸化部位特異的抗体」
「specific」
- adj.
- (～に関して)明確な、はっきりとした(exact precise)、具体的な(in, about)
- (比較)(限定)特定の(particular)、一定の(⇔general)
- (～に)特有の、独特の(to)
- (比較)(医学)(～に)渡航のある(for)。特殊な
- (生物)(生物)種の
- 医学)特異の
- (物理)比の。物質固有の。単位質量・長さ・面積・容積で
n.