有機アニオン輸送・リペプチド2
- 関
- OATP2
WordNet
- simple and healthful and close to nature; "an organic lifestyle"
- a fertilizer that is derived from animal or vegetable matter (同)organic fertilizer, organic fertiliser
- being or relating to or derived from or having properties characteristic of living organisms; "organic life"; "organic growth"; "organic remains found in rock"
- involving or affecting physiology or bodily organs; "an organic disease"
- of or relating to foodstuff grown or raised without synthetic fertilizers or pesticides or hormones; "organic eggs"; "organic vegetables"; "organic chicken"
- relating or belonging to the class of chemical compounds having a carbon basis; "hydrocarbons are organic compounds"
- wind instrument whose sound is produced by means of pipes arranged in sets supplied with air from a bellows and controlled from a large complex musical keyboard (同)pipe_organ
- a fully differentiated structural and functional unit in an animal that is specialized for some particular function
- a government agency or instrument devoted to the performance of some specific function; "The Census Bureau is an organ of the Commerce Department"
- a periodical that is published by a special interest group; "the organ of the communist party"
- a negatively charged ion
- a peptide containing 10 to more than 100 amino acids
- black tropical American cuckoo
PrepTutorEJDIC
- 有機体の,生物の,生物から生じた / (動植物の)器官の / 有機肥料を用いる(を用いて育った)・有機的な,組織的な,系統的な・有機質の
- 『オルガン』,パイプオルガン(pipe organ),リードオルガン(reed organ),電子オルガン(electronic organ),手回しオルガン(barrel organ) / (動植物の)『器官』 / (政党・会社などの)機関誌,機関紙 / 《しばしば複数形で》(行動・実施などの)組織,機関
- 陰イオン
UpToDate Contents
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English Journal
- Polarized location of SLC and ABC drug transporters in monolayer-cultured human hepatocytes.
- Le Vee M1, Jouan E1, Noel G1, Stieger B2, Fardel O3.
- Toxicology in vitro : an international journal published in association with BIBRA.Toxicol In Vitro.2015 Aug;29(5):938-46. doi: 10.1016/j.tiv.2015.03.019. Epub 2015 Apr 7.
- Human hepatocytes cultured in a monolayer configuration represent a well-established in vitro model in liver toxicology, notably used in drug transporter studies. Polarized status of drug transporters, i.e., their coordinated location at sinusoidal or canalicular membranes, remains however incomplet
- PMID 25862123
- Quantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-Glucuronide.
- Varma MV1, Lin J2, Bi YA2, Kimoto E2, Rodrigues AD2.
- Drug metabolism and disposition: the biological fate of chemicals.Drug Metab Dispos.2015 Jul;43(7):1108-18. doi: 10.1124/dmd.115.064303. Epub 2015 May 4.
- Gemfibrozil has been suggested as a sensitive cytochrome P450 2C8 (CYP2C8) inhibitor for clinical investigation by the U.S. Food and Drug Administration and the European Medicines Agency. However, gemfibrozil drug-drug interactions (DDIs) are complex; its major circulating metabolite, gemfibrozil 1-
- PMID 25941268
- Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression.
- Shen H1, Liu T2, Morse BL2, Zhao Y2, Zhang Y2, Qiu X2, Chen C2, Lewin AC2, Wang XT2, Liu G2, Christopher LJ2, Marathe P2, Lai Y2.
- Drug metabolism and disposition: the biological fate of chemicals.Drug Metab Dispos.2015 Jul;43(7):984-93. doi: 10.1124/dmd.114.062364. Epub 2015 Apr 22.
- The contribution of organic anion transporter OAT2 (SLC22A7) to the renal tubular secretion of creatinine and its exact localization in the kidney are reportedly controversial. In the present investigation, the transport of creatinine was assessed in human embryonic kidney (HEK) cells that stably ex
- PMID 25904762
Japanese Journal
- CJK-P-06 Preliminary Study on Thetreatment Mechanism of Yin-Zhi-Huang Granules to Rat Cholestasis Inducedby Estrgen
- Zhang G.Q.,Zhou Y.,Ren J.X.,Zhang J.P.,Zhang F.,Wei Y.H.,Wu XA
- 日本医療薬学会年会講演要旨集 22, 494, 2012-10-10
- NAID 110009619417
- Active intestinal absorption of fluoroquinolone antibacterial agent ciprofloxacin by organic anion transporting polypeptide, Oatp1a5
- Arakawa Hiroshi,Shirasaka Yoshiyuki,Haga Makoto,Nakanishi Takeo,Tamai Ikumi
- Biopharmaceutics and Drug Disposition 33(6), 332-341, 2012-09-00
- … It has been that several fluoroquinolones are substrates of organic anion transporter polypeptides OATP1A2 expressed in human intestine derived Caco-2 cells. …
- NAID 120004997009
- Oral drug delivery utilizing intestinal OATP transporters
- Tamai Ikumi
- Advanced Drug Delivery Reviews 64(6), 508-514, 2012-05-01
- … Recently, organic anion transporting polypeptide (OATP) family such as OATP1A2 and OATP2B1 has been suggested to mediate intestinal absorption of several drugs. …
- NAID 120003386985
★リンクテーブル★
[★]
- 関
- organic anion transporting polypeptide 2
[★]
- 英
- organic anion transporting polypeptide 2、OATP2
[★]
- 関
- organic compound、organic matter、organized、organo
[★]
トランス・ーチン
- 関
- exportin、importin、karyopherin
[★]
- 関
- peptide
[★]
- 関
- anal、anus
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