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1. 変形性関節症の初回薬物療法 initial pharmacologic therapy of osteoarthritis
2. 過敏性腸症候群に対するアロセトロン塩酸塩（Lotronex） alosetron hydrochloride lotronex for irritable bowel syndrome
3. 新生児禁断症候群 neonatal abstinence syndrome
4. クリンダマイシン：概要 clindamycin an overview
5. 成人における急性咽頭炎の対症療法 symptomatic treatment of acute pharyngitis in adults

Combination of electrochemistry with chemometrics to introduce an efficient analytical method for simultaneous quantification of five opium alkaloids in complex matrices.

Gholivand MB1, Jalalvand AR2, Goicoechea HC3, Gargallo R4, Skov T5, Paimard G6.
Talanta.Talanta.2015 Jan;131:26-37. doi: 10.1016/j.talanta.2014.07.053. Epub 2014 Jul 26.
For the first time, an analytical methodology based on differential pulse voltammetry (DPV) at a glassy carbon electrode (GCE) and integration of three efficient strategies including variable selection based on ant colony optimization (ACO), mathematical pre-processing selection by genetic algorithm
PMID 25281069

Metabolic pathway profiling of the derivative of important herbal component noscapine.

Yao Y1, Xiong Y.
European journal of drug metabolism and pharmacokinetics.Eur J Drug Metab Pharmacokinet.2014 Oct 22. [Epub ahead of print]
The present study aims to investigate the influence of metabolic behavior by the introduction of bromo atom into the structure of noscapine. Oral gavage of 50 mg/kg bromo-noscapine for 6- to 8-week-old male mice with C57BL/6 background resulted in the detection of the metabolite undergoing cleavage
PMID 25336326

Jaiswal AS1, Hirsch-Weil D2, Proulx ER2, Hong S3, Narayan S4.
Bioorganic & medicinal chemistry letters.Bioorg Med Chem Lett.2014 Oct 15;24(20):4850-3. doi: 10.1016/j.bmcl.2014.08.053. Epub 2014 Sep 2.
Breast cancer is classified into three groups according to its expression of hormone/growth factor receptors: (i) estrogen receptor (ER) and progesterone receptor (PR)-positive; (ii) human epidermal growth factor receptor 2 (HER2)-positive; and (iii) ER, PR, and HER2-negative (triple-negative). A se
PMID 25240616

増田光宏,佐藤智子,半田光一 [他],伊藤裕二,相楽和彦
分析化学 46(10), 777-783, 1997-10-05
… Nine components in the preparation, such as acetaminophen, anhydrous caffeine, riboflavin, dihydrocodeine phosphate, DL-methylephedrine hydrochloride, carbinoxamine maleate, noscapine, bisibuthiamine and bromhexine hydrochloride, could be completely separated by changing from water-acetonitrile (95 : 5) to water-acetonitrile (1 : 1) as the mobile phase containing 0.1% of phosphoric acid and 0.08 w/v% of sodium heptansulfonate by a linear gradient program. …
NAID 110002907349

緩利昌代,中西弘,谷口徠
分析化学 43(7), 575-580, 1994-07-05
かぜ薬の有効成分の簡便な定量法を検討した.かぜ薬の10成分を塩基性領域で負荷電する化合物及び中性化合物と酸性領域で正荷電する化合物の二つのグループに分類した, アセトアミノフェン, 無水カフェイン, グアイフェネシン, エテンザミド及びグアヤコールスルホン酸カリウムをAグループ, マレイン酸クロルフェニラミン, 臭化水素酸デキストロメトルファン, リン酸ジヒドロコデイン, dl-塩酸メチルエフェド …
NAID 110002906803

森村佳史,河原信吾,石谷昭子,伊藤信彰,平野佳成,内田和人,東裕子,廣田忠臣
奈良医学雑誌 45(2), 248-252, 1994-04-30
… Drugs were extracted from blood, urine, liver, kidney, brains, and contents of the stomach, and qualitative and quantitative estimation of these drugs was carried out by GC and GC-MS. The concentration (μg/ml) of acetaminophen, dihydrocodein-phosphate, dl-methylephedrine-hydrochloride, caffein, and noscapine in theheart blood were 880, 6, 23, 70, and 114, respectively. …
NAID 120004973616