新生児ループス
WordNet
- relating to or affecting the infant during the first month after birth; "neonatal care"; "the neonatal period"
- any of several forms of ulcerative skin disease
- a constellation in the southern hemisphere near Centaurus
PrepTutorEJDIC
- 新生児の
- 狼瘡(ろうそう)(皮膚結核の一種)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2021/09/09 04:56:43」(JST)
[Wiki en表示]
Medical condition
| Neonatal lupus erythematosus |
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| Specialty | Neonatology |
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Neonatal lupus erythematosus is the occurrence of systemic lupus erythematosus (SLE) symptoms in an infant born from a mother with SLE, most commonly presenting with a rash resembling subacute cutaneous lupus erythematosus, and sometimes with systemic abnormalities such as complete heart block or hepatosplenomegaly.[1]
The infants have no skin lesions at birth, but sometimes develop them during the first weeks of life.[2] Neonatal lupus is usually benign and self-limited.[1]
It is associated with mothers who carry the Anti-SSA/Ro antibodies, which is associated most closely with the subacute cutaneous lupus erythematosus form of the disease.[2]
See also
- Lupus erythematosus
- Congenital heart block
References
- ^ a b thefreedictionary.com > neonatal lupus Citing: Dorland's Medical Dictionary for Health Consumers. Copyright 2007
- ^ a b James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. Page 160. ISBN 0-7216-2921-0.
External links
| Classification | D |
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| External resources | - eMedicine: article/1006582
- Orphanet: 398124
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UpToDate Contents
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- 1. 新生児ループス：疫学、発症機序、臨床症状、診断neonatal lupus epidemiology pathogenesis clinical manifestations and diagnosis [show details]
… Neonatal lupus (NL) is an autoimmune disease in which passive transfer of autoantibodies from the mother to the fetus results in fetal and neonatal disease. The major manifestations are cardiac and cutaneous …
- 2. 新生児ループス：マネージメントおよび転帰neonatal lupus management and outcomes [show details]
… Neonatal lupus (NL) is an autoimmune disease that is passively transferred from the mother to the fetus. The major manifestations are cardiac and cutaneous findings. The most serious complication of NL …
- 3. 皮膚エリテマトーデスの概要overview of cutaneous lupus erythematosus [show details]
…birth Congenital heart block is the most concerning complication of neonatal lupus. Following the birth of an infant with neonatal lupus, the risk for congenital heart block is increased with subsequent …
- 4. 抗Ro/SSA抗体および抗La/SSB抗体の抗原抗体系the anti ro ssa and anti la ssb antigen antibody systems [show details]
…who have given birth to a child with neonatal lupus syndrome, the risk of congenital heart block in subsequent pregnancies increases to 15 percent . Neonatal lupus accounts for 90 to 95 percent of cases …
- 5. 先天性第3度（完全）房室ブロックcongenital third degree complete atrioventricular block [show details]
… third degree, with lower-grade block seen only occasionally. The non-cardiac manifestations of neonatal lupus resolve as maternal antibodies dissipate in the infant, but cardiac damage tends to be irreversible…
English Journal
- Benefits of fetal echocardiographic surveillance in pregnancies at risk of congenital heart block: a single centre study of 212 anti-Ro52 positive pregnancies.
- Sonesson SE1, Ambrosi A2, Wahren-Herlenius M2.
- Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.Ultrasound Obstet Gynecol.2019 Jan 8. doi: 10.1002/uog.20214. [Epub ahead of print]
- PMID 30620419
- AuthorsDiaz-Frias J1, Badri T2.
- Open/close author information list" class="jig-ncbitoggler" href="#
- PMID 30252317
- Effect of in utero hydroxychloroquine exposure on the development of cutaneous neonatal lupus erythematosus.
- Barsalou J1, Costedoat-Chalumeau N2, Berhanu A3, Fors-Nieves C4, Shah U5, Brown P6, Laskin CA7, Morel N2, Levesque K2, Buyon JP4, Silverman ED8, Izmirly PM4.
- Annals of the rheumatic diseases.Ann Rheum Dis.2018 Dec;77(12):1742-1749. doi: 10.1136/annrheumdis-2018-213718. Epub 2018 Oct 8.
- PMID 30297329
Japanese Journal
- 症例報告 母親の抗SS-A/SS-B抗体高値より発症が予測されていた新生児エリテマトーデスの1例
- 吉田 春奈,田代 康哉,渡辺 秀晃,末木 博彦
- 臨床皮膚科 = Japanese journal of clinical dermatology 74(13), 1046-1050, 2020-12
- NAID 40022435078
- 妊娠を契機にTMAを発症し死亡に至ったSLE合併妊娠の1例
- 不殿 絢子,江川 真希子,蓬田 裕,羅 ことい,廣瀬 明日香,宮坂 尚幸
- 日本周産期・新生児医学会雑誌 56(2), 324-329, 2020
- <p> 血栓性微小血管症（TMA）は溶血性貧血，血小板減少，血小板血栓による臓器障害の3主徴を呈する症候群で，病態が急激に悪化し致命的となりうる重篤な疾患である．妊娠を契機にTMAを発症し，人工妊娠中絶を行ったが死亡に至ったSLE合併妊娠を経験した．症例は29歳1妊0産．妊娠前は軽度の蛋白尿を認める以外に臓器障害はなく寛解状態と考えられていたが，妊娠9週時に蛋白尿が増悪し，血液検査所見 …
- NAID 130007899058
- 症例 妊娠中のCNS lupusによる痙攣発作が原因の新生児低酸素性虚血性脳症の1例
- 中西 沙由理,笠井 絢子,廣岡 潤子,小畑 聡一朗,高見 美緒,榎本 紀美子,葛西 路,青木 茂
- 産科と婦人科 84(1), 93-96, 2017-01
- NAID 40021038470
Related Links
- Neonatal lupus is an uncommon autoimmune disease manifested primarily by cutaneous lupus lesions and/or congenital heart block. Maternal autoantibodies of the Ro/La family are present in virtually every case, although only approximately 1% of women who have these autoantibodies will have a baby with ….
- Neonatal lupus is not true lupus. It is a rare condition associated with anti-SSA/Ro and/or anti-SSB/La antibodies from the mother that affect the fetus. At birth, the baby may have a skin rash, liver problems, or low blood cell counts, but these symptoms typically disappear completely after six months with no lasting effects.
- Neonatal lupus syndrome is a passively acquired autoimmune syndrome in which pathogenic autoantibodies(anti SSA/Ro, anti SSB/La,andboth,orrarelyanti U 1 RNP antibodies) are transmitted from a mother to her fetus
★リンクテーブル★
[★]
- 英
- neonatal lupus
- 同
- 新生児ループスエリテマトーデス, neonatal lupus erythematosus, NLE
- 関
- 全身性エリテマトーデス
[show details]
概念
- 全身性エリテマトーデスの母体から出生した新生児に認められる。
- SLE類似症状を呈する病態。
- 皮疹、汎血球減少、完全房室ブロック(抗SS-A抗体の移行による。非可逆的)
- 完全房室ブロック以外は生後6ヶ月程度で消失
[★]
新生児ループス、新生児ループスエリテマトーデス, NLE
[★]
- 関
- neonatal period、neonatally、neonate、newborn、newborn animal、newborn infant
[★]
ループス、狼瘡