骨髄性リンパ性白血病タンパク質
WordNet
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- of or relating to the spinal cord
- of or relating to bone marrow
- malignant neoplasm of blood-forming tissues; characterized by abnormal proliferation of leukocytes; one of the four major types of cancer (同)leukaemia, leucaemia, cancer of the blood
- resembling lymph or lymphatic tissues
PrepTutorEJDIC
- 蛋白(たんばく)質
- 白血病
- リンパ状(液)の
UpToDate Contents
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English Journal
- GABP is necessary for stem/progenitor cell maintenance and myeloid differentiation in human hematopoiesis and chronic myeloid leukemia.
- Manukjan G1, Ripperger T2, Venturini L3, Stadler M3, Göhring G2, Schambach A4, Schlegelberger B2, Steinemann D2.
- Stem cell research.Stem Cell Res.2016 Apr 12;16(3):677-681. doi: 10.1016/j.scr.2016.04.007. [Epub ahead of print]
- Maintenance of hematopoietic stem cells and their potential to give rise to progenitors of differentiated lymphoid and myeloid cells are accomplished by a network of regulatory processes. As a part of this network, the heteromeric transcription factor GA-binding protein (GABP) plays a crucial role i
- PMID 27100840
- Distinct GAB2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL1.
- Gu S1, Chan WW2, Mohi G3, Rosenbaum J4, Sayad A5, Lu Z5, Virtanen C5, Li S6, Neel BG1, Van Etten RA2.
- Blood.Blood.2016 Apr 7;127(14):1803-13. doi: 10.1182/blood-2015-06-653006. Epub 2016 Jan 15.
- Tyrosine kinase inhibitors (TKIs) directed against BCR-ABL1, the product of the Philadelphia (Ph) chromosome, have revolutionized treatment of patients with chronic myeloid leukemia (CML). However, acquired resistance to TKIs is a significant clinical problem in CML, and TKI therapy is much less eff
- PMID 26773044
- Differential regulation of the c-Myc/Lin28 axis discriminates subclasses of rearranged MLL leukemia.
- Chen L1, Sun Y1, Wang J1, Jiang H2, Muntean AG1.
- Oncotarget.Oncotarget.2016 Mar 19. doi: 10.18632/oncotarget.8199. [Epub ahead of print]
- MLL rearrangements occur in myeloid and lymphoid leukemias and are generally associated with a poor prognosis, however this varies depending on the fusion partner. We modeled acute myeloid leukemia (AML) in mice using various MLL fusion proteins (MLL-FPs) and observed significantly different surviva
- PMID 27007052
Related Links
- "Myeloid-Lymphoid Leukemia Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). ... Myeloid-lymphoid leukemia protein is a transcription factor that ...
- Definition: Myeloid-lymphoid leukemia protein is a transcription factor that maintains high levels of HOMEOTIC GENE expression during development. The GENE for myeloid-lymphoid leukemia protein is commonly disrupted in ...
Related Pictures
![Myeloid-Lymphoid Leukemia Protein](https://1mg.info/0/9/6/2738.jpg)
![adult acute myeloid leukemia favorable](https://1mg.info/0/9/6/2739.jpg)
![Myeloid-Lymphoid Leukemia Protein](https://1mg.info/0/9/6/2740.jpg)
![Myeloid-Lymphoid Leukemia Protein](https://1mg.info/0/9/6/2741.jpg)
![Myeloid-Lymphoid Leukemia Protein](https://1mg.info/0/9/6/2742.jpg)
★リンクテーブル★
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- 英
- myeloid-lymphoid leukemia protein
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- 関
- BM、bone marrow、myelo、myelocytic、myelogenous
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リンパ性白血病、リンパ様白血病
- 関
- lymphoblastic leukemia、lymphocytic leukaemia、lymphocytic leukemia
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- 関
- lymphatic system
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