変異マウス系統、変異マウス種

WordNet

become stretched or tense or taut; "the bodybuilders neck muscles tensed;" "the rope strained when the weight was attached" (同)tense
(psychology) nervousness resulting from mental stress; "his responsibilities were a constant strain"; "the mental strain of staying alert hour after hour was too much for him" (同)mental strain, nervous strain
(physics) deformation of a physical body under the action of applied forces
injury to a muscle (often caused by overuse); results in swelling and pain
an intense or violent exertion (同)straining
use to the utmost; exert vigorously or to full capacity; "He really extended himself when he climbed Kilimanjaro"; "Dont strain your mind too much" (同)extend
manipulate the mouse of a computer
a hand-operated electronic device that controls the coordinates of a cursor on your computer screen as you move it around on a pad; on the bottom of the device is a ball that rolls on the surface of the pad; "a mouse takes much more room than a trackball" (同)computer mouse
any of numerous small rodents typically resembling diminutive rats having pointed snouts and small ears on elongated bodies with slender usually hairless tails
person who is quiet or timid
tending to undergo or resulting from mutation; "a mutant gene"
an animal that has undergone mutation
(biology) an organism that has characteristics resulting from chromosomal alteration (同)mutation, variation, sport
showing signs of mental and emotional tension; "her voice was strained as she asked the question"

PrepTutorEJDIC

…‘を'『引っ張る』 / (使い過ぎて)〈体など〉‘を'『痛める』,弱める / …‘を'『最大限に働かせる』,精一杯使う / 〈意味・規則など〉‘を'曲げる,こじつける,拡大解釈する / 〈液体〉‘を'『こす』;(液体から)〈固形分〉‘を'こして取る《+『out(off)』+『名』+『from』+『名』》 / 全力を尽くす,懸命に努力する / ぱんと張る / 〈C〉〈U〉『張りつめること』,張る力 / 〈C〉『筋違い』,ねんざ,くじき / 〈U〉(精神的に,極度に)緊張,重荷,過労 / 〈C〉骨のおれる仕事,激務
〈C〉家系,血統,種族 / 〈C〉品種 / 〈U〉《しばしばa ~》(遺伝的な)性質,体質 / 〈C〉《しばしば複数形で》《単数扱い》(音楽の)曲,一節 / 〈C〉口調,言い回し,文体
『ハツカネズミ』(英米の家によく出没する小型のネズミ;ほが国の家に出没する大型のネズミはrat) / 《話》臆病者,内気な人 / 《猫が》ネズミを捜す(捕らえる) / 《人が》(…を)あさり歩く《+『about』+『名』》
突然変異種(堤)
緊張した;疲れた / 不自然な,わざとらしい;こじつけの

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1. アキレス腱に至らない脹脛部の傷害 calf injuries not involving the achilles tendon
2. 遺伝学およびゲノミクスのためのツール：研究用に育種された遺伝子改変マウス tools for genetics and genomics specially bred and genetically engineered mice
3. Natural history, microbiology, and pathogenesis of tuberculosis
4. 淋菌感染の疫学および病因 epidemiology and pathogenesis of neisseria gonorrhoeae infection
5. 異常ヘモグロビン症におけるマラリアに対する防御 protection against malaria in the hemoglobinopathies

English Journal

Characterization of epitopes on the rabies virus glycoprotein by selection and analysis of escape mutants.

Fallahi F1, Wandeler AI2, Nadin-Davis SA3.
Virus research.Virus Res.2016 Jul 15;220:161-71. doi: 10.1016/j.virusres.2016.04.019. Epub 2016 Apr 27.
The glycoprotein (G) is the only surface protein of the lyssavirus particle and the only viral product known to be capable of eliciting the production of neutralizing antibodies. In this study, the isolation of escape mutants resistant to monoclonal antibody (Mab) neutralization was attempted by a s
PMID 27132040

In vitro and in vivo studies of a potent capsid-binding inhibitor of enterovirus 71.

Ho JY1, Chern JH2, Hsieh CF1, Liu ST1, Liu CJ1, Wang YS1, Kuo TW1, Hsu SJ2, Yeh TK2, Shih SR3, Hsieh PW4, Chiu CH5, Horng JT6.
The Journal of antimicrobial chemotherapy.J Antimicrob Chemother.2016 Jul;71(7):1922-32. doi: 10.1093/jac/dkw101. Epub 2016 Apr 19.
OBJECTIVES: Enterovirus 71 (EV-A71) is an important pathogen that can cause severe neurological symptoms and even death. Our aim was to identify potent anti-EV-A71 compounds and study their underlying mechanisms and in vivo activity.METHODS: We identified a potent imidazolidinone derivative (abbrevi
PMID 27098012

Oligoribonuclease is required for the type III secretion system and pathogenesis of Pseudomonas aeruginosa.

Chen G1, Zhao Q2, Zhu F1, Chen R1, Jin Y1, Liu C1, Pan X1, Jin S3, Wu W1, Cheng Z4.
Microbiological research.Microbiol Res.2016 Jul-Aug;188-189:90-6. doi: 10.1016/j.micres.2016.05.002. Epub 2016 May 4.
Oligoribonuclease (Orn) is a 3' to 5' exonuclease that degrades nanoRNAs, which can serve as primers for transcription initiation at a significant fraction of promoters. One of Orn's substrates, pGpG inhibits the enzymatic activity of EAL-domain containing phosphodiesterases (PDEs), thereby increasi
PMID 27296966

Japanese Journal

Functional Differences between GDNF-Dependent and FGF2-Dependent Mouse Spermatogonial Stem Cell Self-Renewal

Stem Cell Reports 4(3), 489-502, 2015-02
NAID 120005540400

Immunological study of an attenuated Salmonella Typhimurium expressing ApxIA, ApxIIA, ApxIIIA and OmpA of Actinobacillus pleuropneumoniae in a mouse model

Journal of Veterinary Medical Science 77(12), 1693-1696, 2015
NAID 130005115342

Immunological study of an attenuated Salmonella Typhimurium expressing ApxIA, ApxIIA, ApxIIIA and OmpA of Actinobacillus pleuropneumoniae in a mouse model