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Development and usage of protein microarrays for the quantitative measurement of Panton-Valentine leukocidin.

Stieber B1, Monecke S2, Müller E3, Baier V3, W Coombs G4, Ehricht R3.
Molecular and cellular probes.Mol Cell Probes.2014 Aug;28(4):123-32. doi: 10.1016/j.mcp.2013.11.003. Epub 2013 Dec 3.
Staphylococcus aureus is a human pathogen that can harbour several genes encoding exotoxins including leukocidins. A clinically most relevant factor is Panton-Valentine leukocidin (PVL) because of its association with chronic, recurrent or severe skin and soft tissue infections. In this study an ant
PMID 24308917

Anti-VEGF antibody therapy induces tumor hypoxia and stanniocalcin 2 expression and potentiates growth of human colon cancer xenografts.

Miyazaki S1, Kikuchi H, Iino I, Uehara T, Setoguchi T, Fujita T, Hiramatsu Y, Ohta M, Kamiya K, Kitagawa K, Kitagawa M, Baba S, Konno H.
International journal of cancer. Journal international du cancer.Int J Cancer.2014 Jul 15;135(2):295-307. doi: 10.1002/ijc.28686. Epub 2014 Jan 6.
Tumor angiogenesis plays a critical role in colorectal cancer progression. Recent randomized clinical trials have revealed the additive effect of bevacizumab, a humanized monoclonal antibody against vascular endothelial growth factor (VEGF)-A, to conventional chemotherapy in the improved survival of
PMID 24375080

The clinical significance of downregulation of mir-124-3p, mir-146a-5p, mir-155-5p and mir-335-5p in gastric cancer tumorigenesis.

Li H1, Xie S2, Liu M1, Chen Z1, Liu X1, Wang L1, Li D1, Zhou Y1.
International journal of oncology.Int J Oncol.2014 Jul;45(1):197-208. doi: 10.3892/ijo.2014.2415. Epub 2014 May 6.
Dysregulated miRNAs in gastric cancer are usually screened by miRNA microarray from clinical samples, however, reports have indicated that results of each miRNA microarray screening are considerably different, and dysregulated miRNAs, especially downregulated miRNAs were contradictory. In view of th
PMID 24805774

Different Responses to 5-fluoraouracil in Mutagenicity and Gene Expression between Two Human Lymphoblastoid Cell Lines with or without TP53 Mutation

Oka Hiroaki,Ouchida Mamoru,Kondo Takuya,Morita Fumio,Shimizu Kenji
Acta Medica Okayama 66(2), 119-129, 2012-04
… The effects of 5-FU on gene expression were assessed by microarray and quantitative RT-PCR analyses. …
NAID 120004040527

The KEGG databases and tools facilitating omics analysis: latest developments involving human diseases and pharmaceuticals.

Kotera Masaaki,Hirakawa Mika,Tokimatsu Toshiaki,Goto Susumu,Kanehisa Minoru
Methods in molecular biology 802, 19-39, 2012
… The desktop application KegArray and many Web-based tools are tightly integrated with the KEGG knowledgebase, which helps visualize and interpret large amount of data derived from high-throughput measurement techniques including microarray, metagenome, and metabolome analyses. …
NAID 120003726147