WordNet

a concavity in a surface produced by pressing; "he left the impression of his fingers in the soft mud" (同)impression, imprint
a long-term economic state characterized by unemployment and low prices and low levels of trade and investment (同)slump, economic crisis
a mental state characterized by a pessimistic sense of inadequacy and a despondent lack of activity
angular distance below the horizon (especially of a celestial object)
pushing down; "depression of the space bar on the typewriter"
sad feelings of gloom and inadequacy
someone subject to melancholia (同)melancholiac
a period during the 1930s when there was a worldwide economic depression and mass unemployment (同)Great_Depression

PrepTutorEJDIC

〈C〉『くぼ地』,くぼみ / 〈U〉〈C〉『意気消沈』,憂うつ;うつ病 / 〈C〉『不景気』,不況 / 〈U〉押し下げること,降下,低下
憂うつな,ふさぎ込んだ / うつ病の,うつ病にかかった

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/10/08 22:22:14」(JST)

wiki en

Melancholic depression.

Melancholic depression, or 'depression with melancholic features', is a DSM-IV subtype of major depression requiring at least one of the following symptoms: anhedonia (the inability to find pleasure in positive things), or lack of mood reactivity (i.e. mood does not improve in response to positive events) and at least three of the following: depression that is subjectively different from grief or loss, severe weight loss or loss of appetite, psychomotor agitation or retardation, early morning awakening, guilt that is excessive, and worse mood in the morning. Melancholic features apply to an episode of depression that occurs as part of either major depressive disorder or bipolar disorder I or II.^[1]

Melancholic depression is often considered to be a biologically based and particularly severe form of depression.^[2] Treatment involves antidepressants, electroconvulsive therapy, or other empirically supported treatments such as cognitive behavioral therapy and interpersonal therapy for depression.^[3] A 2008 analysis of a large study of patients with unipolar major depression found a rate of 23.5% for melancholic features.^[2] It was the first form of depression extensively studied, and many of the early symptom checklists for depression reflect this. The incidence of melancholic depression has been found to increase when the temperature and/or sunlight are low.^[4] According to the DSM-IV, the "melancholic features" specifier may be applied to the following only:

Major depressive episode, single episode
Major depressive episode, recurrent episode
Bipolar I disorder, most recent episode depressed
Bipolar II disorder, most recent episode depressed

Causes

The causes of melancholic type major depressive disorder are believed to be mostly due to biological factors; some may have inherited the disorder from their parents. Sometimes stressful situations can trigger episodes of melancholic depression, though this is a contributing cause rather than a necessary or sufficient cause. It has also been found that melancholic symptoms are common in people who suffer from bipolar I disorder and may often be present in people with bipolar II disorder. People with psychotic symptoms are also thought to be more susceptible to this disorder. It is frequent in old age and often unnoticed by some physicians who perceive the symptoms to be a part of dementia. Major depressive disorder, melancholic or otherwise, is a separate condition that can be comorbid with dementia in the elderly.^[5]

References

^ Diagnostic and Statistical Manual of Mental Disorders - Text Revision. Arlington VA: American Psychiatric Publishing. 2008. pp. 419–420. ISBN 978-0-89042-025-6.
^ ^a ^b McGrath, Patrick; Ashan Khan, Madhukar Trivedi, Jonathan Stewart, David W Morris, Stephen Wisniewski, Sachiko Miyahara, Andrew Nierenberg, Maurizio Fava, John Rush, (2008). "Response to a Selective Serotonin Reuptake Inhibitor (Citalopram) in Major Depressive Disorder with Melancholic Features: A STAR*D Report". Journal of Clinical Psychiatry 69: 1847–1855.
^ Luty, Suzanne; Carter, Janet; McKenzie, Janice (2007). "Randomised controlled trial of interpersonal psychotherapy and cognitive-behavioural therapy for depression". The British Journal of Psychiatry 190: 496–502. doi:10.1192/bjp.bp.106.024729.
^ Radua, Joaquim; Pertusa, Alberto; Cardoner, Narcis (28 February 2010). "Climatic relationships with specific clinical subtypes of depression". Psychiatry Research 175 (3): 217–220. doi:10.1016/j.psychres.2008.10.025. PMID 20045197.
^ Pekker, Michael. [Melancholic depression has a short spontaneous reduction rate. It is treated best with physical treatments (for example antidepressant drugs) and only slightly (at best) to non-physical treatments such as counseling or psychotherapy "Clinical Depression: Symptoms and Treatments"]. Melancholic depression has a short spontaneous reduction rate. It is treated best with physical treatments (for example antidepressant drugs) and only slightly (at best) to non-physical treatments such as counseling or psychotherapy. Retrieved 12 October 2011.

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 成人における単極性うつ病 unipolar depression in adults clinical features
2. 成人における単極性うつ病：評価および診断 unipolar depression in adults assessment and diagnosis
3. 高齢者における単極性うつ病の診断およびマネージメント diagnosis and management of late life unipolar depression
4. 成人における単極性うつ病：初期治療の選択 unipolar major depression in adults choosing initial treatment
5. 成人における単極性うつ病：抗うつ剤併用による治療 unipolar depression in adults treatment with antidepressant combinations

English Journal

Osmophobia and allodynia are critical factors for suicidality in patients with migraine.

Park SP1, Seo JG, Lee WK.
The journal of headache and pain.J Headache Pain.2015 Dec;16(1):529. doi: 10.1186/s10194-015-0529-1. Epub 2015 May 12.
BACKGROUND: Sensory hypersensitivities are common phenomena in migraine. We examined the role of sensory hypersensitivities on suicidality in patients with migraine.METHODS: Patients with migraine (with or without aura) were consecutively recruited from our headache clinic. We asked them if they exp
PMID 25968102

Widespread white matter but focal gray matter alterations in depressed individuals with thoughts of death.

Taylor WD1, Boyd B2, McQuoid DR3, Kudra K2, Saleh A2, MacFall JR4.
Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2015 Oct 1;62:22-8. doi: 10.1016/j.pnpbp.2015.05.001. Epub 2015 May 8.
BACKGROUND: Past work demonstrates that depressed individuals with suicidal thoughts or behaviors exhibit specific neuroanatomical alterations. This may represent a distinct phenotype characterized by specific findings on neuroimaging, but it is unclear if these findings extend to individuals with m
PMID 25963377

The NVL gene confers risk for both major depressive disorder and schizophrenia in the Han Chinese population.

Wang M1, Chen J2, He K3, Wang Q4, Li Z1, Shen J1, Wen Z1, Song Z1, Xu Y4, Shi Y5.
Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2015 Oct 1;62:7-13. doi: 10.1016/j.pnpbp.2015.04.001. Epub 2015 Apr 17.
NVL (nuclear VCP (valosin containing protein)/p97-Like), a member of the AAA-ATPase (ATPases associated with various cellular activities) family, encodes a novel hTERT (human telomerase reverse transcriptase)-interacting protein NVL2 which is a telomerase component essential for holoenzyme assembly.
PMID 25891250

Japanese Journal

現代の「うつ」とは何か? : 「うつ」が主訴となる時代 (特集「うつ」の現在)

春日武彦
臨床心理学 12(4), 464-468, 2012-07
NAID 40019324958

エミール・シオランの神 : 神の喪失と神への情動

藤本拓也
宗教研究 85(3), 693-716, 2011-12-30
二十世紀フランスの思想家エミール・シオランは、無信仰者と自己規定しつつ、一方で神への渇望をしばしば語っている。シオランの神に対するアンビヴァレントな態度は、メランコリー=鬱という情動と強く結びついたものである。すなわち、メランコリーにおいて神の喪失が悲しまれ、同時に、不在の神に対する憎しみや怒りが吐露されるのである。こうしたシオランの姿勢に窺われるのは、神を感じる主体の情動を問題にする思考である。 …
NAID 110008799193

うつ病と日本的ナルシシズムについて

堀有伸
臨床精神病理 32(2), 95-117, 2011-08-30
NAID 10029855834

「メランコリー型うつ病」

　　[★]

英: melancholic depression
関: メランコリー型性格、うつ病

「depression」

　　[★]

同: D, 低下、うつ病

n.

押し下げること、下降、沈下、陥没
くぼみ、窪地、低地、陥凹
意気消沈、憂鬱、ふさぎ。(精神医)鬱病、よくうつ、メランコリー
不振、低下、減退。(経済)不景気、不況
(生理)機能低下

[DSM-IV_TR-0] Diagnostic and Statistical Manual of Mental Disorders - Text Revision. Arlington VA: American Psychiatric Publishing. 2008. pp. 419–420. ISBN 978-0-89042-025-6.

[McGrath_2008-1] McGrath, Patrick; Ashan Khan, Madhukar Trivedi, Jonathan Stewart, David W Morris, Stephen Wisniewski, Sachiko Miyahara, Andrew Nierenberg, Maurizio Fava, John Rush, (2008). "Response to a Selective Serotonin Reuptake Inhibitor (Citalopram) in Major Depressive Disorder with Melancholic Features: A STAR*D Report". Journal of Clinical Psychiatry 69: 1847–1855.

[Luty2007-2] Luty, Suzanne; Carter, Janet; McKenzie, Janice (2007). "Randomised controlled trial of interpersonal psychotherapy and cognitive-behavioural therapy for depression". The British Journal of Psychiatry 190: 496–502. doi:10.1192/bjp.bp.106.024729.

[radua2010-3] Radua, Joaquim; Pertusa, Alberto; Cardoner, Narcis (28 February 2010). "Climatic relationships with specific clinical subtypes of depression". Psychiatry Research 175 (3): 217–220. doi:10.1016/j.psychres.2008.10.025. PMID 20045197.

[4] Pekker, Michael. [Melancholic depression has a short spontaneous reduction rate. It is treated best with physical treatments (for example antidepressant drugs) and only slightly (at best) to non-physical treatments such as counseling or psychotherapy "Clinical Depression: Symptoms and Treatments"]. Melancholic depression has a short spontaneous reduction rate. It is treated best with physical treatments (for example antidepressant drugs) and only slightly (at best) to non-physical treatments such as counseling or psychotherapy. Retrieved 12 October 2011.

匿名

検索

案内

案内

melancholic depression