肺液
WordNet
- smooth and flowing in quality; entirely free of harshness; "the liquid song of a robin"
- the state in which a substance exhibits a characteristic readiness to flow with little or no tendency to disperse and relatively high incompressibility (同)liquidness, liquidity, liquid state
- a substance that is liquid at room temperature and pressure
- fluid matter having no fixed shape but a fixed volume
- a frictionless continuant that is not a nasal consonant (especially `l and `r'
- clear and bright; "the liquid air of a spring morning"; "eyes shining with a liquid luster"; "limpid blue eyes" (同)limpid
- filled or brimming with tears; "swimming eyes"; "sorrow made the eyes of many grow liquid" (同)swimming
- existing as or having characteristics of a liquid; especially tending to flow; "water and milk and blood are liquid substances"
- either of two saclike respiratory organs in the chest of vertebrates; serves to remove carbon dioxide and provide oxygen to the blood
PrepTutorEJDIC
- 『液体』,流体 / 『液体の』,液状の / (空気・水などが)澄んだ,透明な / (音・調子などが)なめらかな,流れるような;(動作などが)なめらかな / (資産・証券・紙幣などが)流動性の(現金化しやすいこと)
- 《しばしば複数形で》『肺』,肺臓
UpToDate Contents
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English Journal
- Pore size-dependent immunogenic activity of mesoporous silica-based adjuvants in cancer immunotherapy.
- Wang X1, Li X, Ito A, Sogo Y, Ohno T.Author information 1Human Technology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, 305-8566, Japan.AbstractCommonly used aluminum hydroxide (Alum) adjuvant provokes a strong type 2 helper T cell (Th2) response for mediating antibody production but is rather ineffective for disease prevention that requires type 1 helper T cell (Th1) response for mediating cellular immunity in human vaccination. Here, for the purpose of inducing Th1 antitumor immunity, a mesoporous silica (MS)-based adjuvant is prepared. Three kinds of MS particles with nearly identical particle size and surface area but different pore sizes of 4, 7 and 10 nm were prepared. No serious in vitro cytotoxicity was observed for the MS particles at 5, 20, 50, and 100 μg/mL. Pathogen-associated molecular patterns (PAMPs) were immobilized with apatite (Ap) on MS to prepare the MS-based and PAMP-loaded adjuvants (MS-Ap-PAMP adjuvants). Macrophage-like cells cultured in the presence of MS-Ap-PAMP adjuvant with a MS pore size of 10 nm showed the maximum in vitro immunogenic activity. Injection of the MS-Ap-PAMP adjuvant with a MS pore size of 10 nm in combination with liquid nitrogen-treated tumor tissue (derived from Lewis lung carcinoma cells) to C57BL/6 mice markedly inhibited the development of rechallenged tumor in vivo, while no such antitumor immunity was induced in injection of Alum mixed with PAMP in combination with liquid nitrogen-treated tumor tissue. The MS-Ap-PAMP adjuvant contributed to the elicitation of a potent systemic Th1 antitumor immunity in vivo. © 2013 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 102A: 967-974, 2014.
- Journal of biomedical materials research. Part A.J Biomed Mater Res A.2014 Apr;102(4):967-74. doi: 10.1002/jbm.a.34783. Epub 2013 May 28.
- Commonly used aluminum hydroxide (Alum) adjuvant provokes a strong type 2 helper T cell (Th2) response for mediating antibody production but is rather ineffective for disease prevention that requires type 1 helper T cell (Th1) response for mediating cellular immunity in human vaccination. Here, for
- PMID 23650285
- Regulation and function of antimicrobial peptides in immunity and diseases of the lung.
- Seiler F, Lepper PM, Bals R, Beisswenger C1.Author information 1Universitat des Saarlandes, Klinik fur Innere Medizin V - Pneumologie, Allergologie, Beatmungsmedizin, D-66421 Homburg/Saar. christoph.beisswenger@uks.eu.AbstractCationic antimicrobial peptides (AMPs) are among the best studied antimicrobial factors expressed in the respiratory tract. AMPs are released by epithelial cells and immune cells into the airway surface liquid covering the epithelial surfaces of the lung where they act as endogenous antibiotics. Plenty of studies showed that AMPs possess additional, often immunomodulatory functions besides their antimicrobial activities. AMPs are chemotactic for immune cells and modulate cellular mechanisms, such as proliferation of epithelial cells, epithelial regeneration, and angiogenesis. The expression and activity of AMPs are impacted by lung diseases and AMPs can have adverse effects in lung diseases. In this review, we discuss the regulation and functions of AMPs in host defense and respiratory tract diseases.
- Protein and peptide letters.Protein Pept Lett.2014 Apr;21(4):341-51.
- Cationic antimicrobial peptides (AMPs) are among the best studied antimicrobial factors expressed in the respiratory tract. AMPs are released by epithelial cells and immune cells into the airway surface liquid covering the epithelial surfaces of the lung where they act as endogenous antibiotics. Ple
- PMID 24164270
- Quality control and identification of steroid saponins from Dioscorea zingiberensis C. H. Wright by fingerprint with HPLC-ELSD and HPLC-ESI-Quadrupole/Time-of-fight tandem mass spectrometry.
- Zhang X1, Liang J1, Liu J1, Zhao Y1, Gao J2, Sun W3, Ito Y4.Author information 1Biomedicine Key Laboratory of Shaanxi Province, Northwest University, No. 229 Taibai North Road, Xi'an, 710069, China.2Shaanxi Jiahe Phytochem Co., Ltd, Xi'an, 710069, China.3Biomedicine Key Laboratory of Shaanxi Province, Northwest University, No. 229 Taibai North Road, Xi'an, 710069, China. Electronic address: guoxiaolizhang@163.com.4Laboratory of Bioseparation Technology, Biochemistry and Biophysics Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: itoy@nhlbi.nih.gov.AbstractIn this study, a fingerprint of steroid saponins, the major bioactive constituents in the crude extracts from Dioscorea zingiberensis C. H. Wright (DZW), has been established for the first time by combined use of the following two methods: high-performance liquid chromatography coupled with evaporative light scattering detector (HPLC-ELSD) and the simultaneous characterization of the steroid saponins by high-performance liquid chromatography coupled with electrospray ionization-mass spectrometry and quadrupole tandem time-of-fight mass analyzers detection (HPLC-ESI-Q/TOF). All HPLC analyses were carried out on a Welchrom C18 column (250mm×4.6mm I.D., 5μm) with a mobile phase composed of water and acetonitrile under gradient elution. There were 68 common characteristic peaks in the fingerprints, in which 12 of them were confirmed by comparing their mass spectra and retention times with those of the reference compounds. In order to identify other unknown peaks, their fragmentation behaviors characteristic of the major groups of steroid saponins from DZW with six types of aglycone skeletons were discussed in detail, and possible MS/MS fragmentation pathways were proposed for aiding the structural identification of these components. According to the summarized fragmentation patterns, these peaks were tentatively assigned by matching their empirical molecular formula with those of the published compounds, or by elucidating their quasi-molecular ions and fragment ions referring to available literature information when the reference standards were unavailable. As a result, 22 new steroid saponins were found in DZW for the first time. In addition, the quantitative analysis of the nine (except for the reference compounds A, B, and C) known peaks was accomplished at the same time which indicated that there was a great variability in the amount of these active compounds in different batches in the crude extracts. This approach could demonstrate that the fingerprint could be considered to be a suitable tool to comprehensively improve the quality control of DZW. The identification and structural elucidation of the peaks in the fingerprint may provide important experimental data for further pharmacological and clinical researches.
- Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2014 Mar 25;91:46-59. doi: 10.1016/j.jpba.2013.11.023. Epub 2013 Nov 27.
- In this study, a fingerprint of steroid saponins, the major bioactive constituents in the crude extracts from Dioscorea zingiberensis C. H. Wright (DZW), has been established for the first time by combined use of the following two methods: high-performance liquid chromatography coupled with evaporat
- PMID 24418811
Japanese Journal
- アミノインデックス®がんリスクスクリーニング(AICS)と各種腫瘍マーカーとの比較検討
- 宮城 洋平,東山 聖彦,合地 明,石川 孝,猿木 信裕,赤池 信,坂東 悦郎,新行内 雅斗,塩澤 学,今村 文生,山本 浩史,新原 温子,岡本 直幸
- 人間ドック (Ningen Dock) 29(4), 585-591, 2014
- 目的:がん患者と健常者の血漿中アミノ酸濃度(PFAA)のバランスの違いを「アミノインデックス技術」を用いて統計解析し,がん罹患の確率を評価する新規がん検診法として,アミノインデックス®がんリスクスクリーニング(AICS)が開発され,複数のがん種に対するスクリーニング検査として実用化されている.本報では,各種がんに対する,AICSと従来の腫瘍マーカーの感度の比較データおよび併用効果について報告する. …
- NAID 130005063933
- Early Onset of Ventilatory and Airway Response to Hypercapnia is Mediated by Medullary 5-HT1A Receptors in Infant Rats
- , , , ,
- The Showa University Journal of Medical Sciences 26(3), 211-217, 2014
- … The DMM includes the solitary tract nucleus, which receives primary afferent inputs from the lung, and the hypoglossal nucleus, which affects genioglossal muscle tone. … 5-HT concentration was measured using high-performance liquid chromatography with electrochemical detection. …
- NAID 130004841525
- 曽根 由美子,上田 暢彦,勝俣 道夫
- 西日本皮膚科 76(3), 214-217, 2014
- 81 歳,男性。1992 年,左腎細胞癌と診断され,左腎摘出術を施行された。2007 年,左前額部に暗赤色の結節が出現した。結節は小豆大でドーム状に隆起しており,血管拡張性肉芽腫様の外観を呈していた。 当科受診後,本人の希望により姑息的に液体窒素凍結療法にて加療していたが,2011 年,喀血の精査時に施行した CT 検査にて右肺・右腎・右腸骨筋・左大腰筋・腹壁への左腎細胞癌の多発性転移が判明した。 …
- NAID 130004691118
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Related Pictures
★リンクテーブル★
[★]
- 英
- lung fluid, lung liquid
- 関
- 肺水
[★]
- 英
- lung liquid
- 同
- 肺液
[★]
- 関
- fluid、fluidal