liver-kidney microsomal antibody

抗LKM抗体

WordNet

1. pursue a positive and satisfying existence; "You must accept yourself and others if you really want to live"
2. actually being performed at the time of hearing or viewing; "a live television program"; "brought to you live from Lincoln Center"; "live entertainment involves performers actually in the physical presence of a live audience" (同)unrecorded
3. abounding with life and energy; "the club members are a really live bunch"
4. charged with an explosive; "live ammunition"; "a live bomb"
5. exerting force or containing energy; "live coals"; "tossed a live cigarette out the window"; "got a shock from a live wire"; "live ore is unmined ore"; "a live bomb"; "a live ball is one in play"
6. highly reverberant; "a live concert hall"
7. in current use or ready for use; "live copy is ready to be set in type or already set but not yet proofread"
8. lead a certain kind of life; live in a certain style; "we had to live frugally after the war"
9. not recorded; "the opera was broadcast live"
10. of current relevance; "a live issue"; "still a live option"
11. a person who has a special life style; "a high liver"
12. large and complicated reddish-brown glandular organ located in the upper right portion of the abdominal cavity; secretes bile and functions in metabolism of protein and carbohydrate and fat; synthesizes substances involved in the clotting of the blood; sy
13. liver of an animal used as meat
14. someone who lives in a place; "a liver in cities"
15. either of two bean-shaped excretory organs that filter wastes (especially urea) from the blood and excrete them and water in urine; "urine passes out of the kidney through ureters to the bladder"
16. any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
17. of or relating to microsomes

PrepTutorEJDIC

1. 『生きている』,生命がある / 《副詞[句]を伴って》〈人などが〉『生き続ける』 / 〈物事が〉長く続く,存続する / 《場所を表す副詞[句]を伴って》〈人などが〉『住む』,居住する / 《副詞[句]を伴って》『生活する』,暮らす / 生人を楽しむ,おもしろく桟らす / 《a+形容詞癌lifeを目的語にして》〈…を生活〉‘を'する / 〈思想など〉‘を'実銭する
2. 《名詞の前にのみ用いて》『生きている』 / 『活気のある』 / (問題などが)当面の / 燃えている / (弾丸などが)まだ爆発してない,未発の / まだ動いている(働いている),有効な / 電流が通じている / (放走が)生の,実況の
3. (ある態度で)生活する人;居住者
4. 〈C〉『肝臓』 / 〈U〉(食用にする)動物の肝臓,レバー
5. 腎臓;(食品としての)羊(豚など)の腎臓 / 《文》気質,性質,たち(nature)
6. 抗体,免疫体,抗毒素

UpToDate Contents

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• 1. 自己免疫性肝炎：血清学的マーカー autoimmune hepatitis serologic markers
• 2. 肝疾患におけるインターフェロン療法の原則および自己免疫の誘導 principles of interferon therapy in liver disease and the induction of autoimmunity
• 3. C型肝炎ウイルス感染の肝外症状 extrahepatic manifestations of hepatitis c virus infection
• 4. 妊娠中の甲状腺疾患の概要 overview of thyroid disease in pregnancy
• 5. 妊娠していない女性の潜在性甲状腺機能低下症 subclinical hypothyroidism in nonpregnant adults

English Journal

• Serology in autoimmune hepatitis: A clinical-practice approach.

• Terziroli Beretta-Piccoli B1, Mieli-Vergani G2, Vergani D3.
• European journal of internal medicine.Eur J Intern Med.2017 Oct 19. pii: S0953-6205(17)30414-4. doi: 10.1016/j.ejim.2017.10.006. [Epub ahead of print]
• PMID 29056396

• Autoimmune Hepatitis: Diagnostic Dilemma When It Is Disguised as Iron Overload Syndrome.

• Acharya GK1, Liao HI2, Frunza-Stefan S2, Patel R2, Khaing M2.
• Journal of clinical and experimental hepatology.J Clin Exp Hepatol.2017 Sep;7(3):269-273. doi: 10.1016/j.jceh.2017.03.006. Epub 2017 Mar 16.
• PMID 28970716

• Recreational Exposure during Algal Bloom in Carrasco Beach, Uruguay: A Liver Failure Case Report.

• Vidal F1, Sedan D2, D'Agostino D3, Cavalieri ML4, Mullen E5, Parot Varela MM6, Flores C7, Caixach J8, Andrinolo D9.
• Toxins.Toxins (Basel).2017 Aug 31;9(9). pii: E267. doi: 10.3390/toxins9090267.
• PMID 28858213

Japanese Journal

• LKM-1 Sera from Autoimmune Hepatitis Patients that Recognize ERp57, Carboxylesterase 1 and CYP2D6

• KOMURASAKI Ryo,IMAOKA Susumu,TADA Naomichi,OKADA Kazushi,NISHIGUCHI Shuhei,FUNAE Yoshihiko
• Drug metabolism and pharmacokinetics 25(1), 84-92, 2010-02-25
• NAID 10027582005

• Current Status of Autoimmune Hepatitis in Japan

• Miyake Yasuhiro,Yamamoto Kazuhide
• Acta Medica Okayama 62(4), 217-226, 2008-08
• … AIH is classified into 3 sub-types based on the profiles of circulating autoantibodies: anti-nuclear antibody and/or smooth muscle antibody-positive (type 1), anti-liver-kidney microsomal antibody-positive (type 2), and anti-soluble liver antigen/liver-pancreas antigen antibody- positive (type 3). …
• NAID 120002305853

• A New Epitope of CYP2D6 Recognized by Liver Kidney Microsomal Autoantibody from Japanese Patients with Autoimmune Hepatitis(Pharmacology)

• , , [他], , , ,
• Biological & pharmaceutical bulletin 28(12), 2240-2243, 2005-12-01
• … Liver-kidney microsomal antibodies type 1 (LKM-1) are a diagnostic marker for autoimmune hepatitis type II (AIH-II). …
• NAID 110004049123

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★リンクテーブル★

リンク元	「抗LKM抗体」
関連記事	「live」「microsomal」「liver」「kidney」

「抗LKM抗体」

　　[★]

英

anti-liver-kidney microsome antibody

同

LKM抗体 liver-kidney microsomal antibody

関

自己免疫性肝炎、抗LKM-1抗体

• 慢性活動性肝炎患者で見いだされた自己抗体で、腎では近位尿細管上皮細胞が選択的に染色され、細胞質が均一に染色される(LAB.894)
• 抗LKM-1抗体は自己免疫性肝炎II型に特徴的
• 対応抗原は50kDa蛋白のcytochrome P450 IID6(CYP450II D6) (LAB.894)

「live」

　　[★]

[liv]

• vt.
• vi.

---

[laiv]

• adj.

同

LAIV

　 　 　 　 　 　 　 　 　 　 　 　

「microsomal」

　　[★]

• adj.

• ミクロソームの

関

microsome

　

「liver」

　　[★] 肝臓 　 　 　 　 　 　

「kidney」

　　[★] 腎臓

同

KUB