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《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
抑制する人(物) / 化学反応抑制剤
OLD French古[代]フランス語

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1. 血管新生阻害剤の概要 overview of angiogenesis inhibitors
2. 男性性機能不全の治療 treatment of male sexual dysfunction
3. 進行腎明細胞癌または転移性腎明細胞癌に対する抗血管新生療法および分子標的療法 anti angiogenic and molecularly targeted therapy for advanced or metastatic clear cell renal cell carcinoma
4. 心血管疾患患者における性的活動 sexual activity in patients with cardiovascular disease
5. 早期再分極 early repolarization

Anoctamin 1 (Ano1) is required for glucose-induced membrane potential oscillations and insulin secretion by murine β-cells.

Crutzen R1, Virreira M1, Markadieu N1, Shlyonsky V2, Sener A2, Malaisse WJ3, Beauwens R4, Boom A5, Golstein PE2.
Pflugers Archiv : European journal of physiology.Pflugers Arch.2015 Nov 18. [Epub ahead of print]
Anions such as Cl- and HCO3 - are well known to play an important role in glucose-stimulated insulin secretion (GSIS). In this study, we demonstrate that glucose-induced Cl- efflux from β-cells is mediated by the Ca2+-activated Cl- channel anoctamin 1 (Ano1). Ano1 expression in rat β-cells is demo
PMID 26582426

The positive frequency-dependent electrophysiological effects of the IKur inhibitor XEN-D0103 are desirable for the treatment of atrial fibrillation.

Ford J1, Milnes J1, El Haou S1, Wettwer E2, Loose S2, Matschke K3, Tyl B4, Round P1, Ravens U5.
Heart rhythm : the official journal of the Heart Rhythm Society.Heart Rhythm.2015 Oct 13. pii: S1547-5271(15)01244-8. doi: 10.1016/j.hrthm.2015.10.003. [Epub ahead of print]
BACKGROUND: Selective inhibitors of Kv1.5 channels are being developed for the treatment of atrial fibrillation (AF).OBJECTIVES: The purpose of this study was to investigate the effects of the highly selective Kv1.5 inhibitor XEN-D0103 on human atrial action potentials (APs) at high excitation rates
PMID 26455450

Small-conductance Ca2+-activated K+ current is upregulated via the phosphorylation of CaMKII in cardiac hypertrophy from spontaneously hypertensive rats.

Mizukami K1, Yokoshiki H2, Mitsuyama H1, Watanabe M1, Tenma T1, Takada S1, Tsutsui H1.
American journal of physiology. Heart and circulatory physiology.Am J Physiol Heart Circ Physiol.2015 Sep 15;309(6):H1066-74. doi: 10.1152/ajpheart.00825.2014. Epub 2015 Aug 21.
Left ventricular hypertrophy is associated with an increased risk of ventricular arrhythmias. However, the underlying molecular basis is poorly understood. It has been reported that small-conductance Ca(2+)-activated K(+) (SK) channels are involved in the pathogenesis of ventricular arrhythmias in h
PMID 26297230