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- repolarize
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/07/08 21:02:11」(JST)
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In neuroscience, repolarization refers to the change in membrane potential that returns it to a negative value just after the depolarization phase of an action potential has changed the membrane potential to a positive value. The repolarization phase usually returns the membrane potential back to the resting membrane potential. The efflux of K+ ions results in the falling phase of an action potential. The ions pass through the selectivity filter of the K+ channel pore. There are several K+ channels that contribute to repolarization, including A-type channels, delayed rectifiers, and Ca2+-activated K+ channels.[1]
Repolarization typically results from the movement of positively charged K+ ions out of the cell. The repolarization phase of an action potential initially results in hyperpolarization, attainment of a membrane potential, termed the afterhyperpolarization, that is more negative than the resting potential. Repolarization usually takes several miliseconds.[2]
References
- ^ Purves D, Augustine GJ, Fitzpatrick D et al., eds. (2001). Neuroscience (2. ed.). Sunderland, Mass: Sinauer Assoc. ISBN 0-87893-742-0.
- ^ Jeff Hardin; Gregory Paul Bertoni; Lewis J. Kleinsmith. Becker's World of the Cell. Benjamin-Cummings Publishing Company; December 2010. ISBN 978-0-321-71602-6. p. 389.
External links
- "Repolarization (Animation)". Psychology Department, Hanover College. Retrieved 18 May 2013.
UpToDate Contents
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English Journal
- Relationships of electrocardiographic parameters with ambulatory hypertension in young and healthy adults.
- Aeschbacher S1, Metin F1, Bossard M2, Schoen T2, von Rotz M1, Mettler H3, Abächerli R4, Risch M5, Risch L6, Conen D7.
- International journal of cardiology.Int J Cardiol.2016 Jan 1;202:300-4. doi: 10.1016/j.ijcard.2015.09.013. Epub 2015 Sep 13.
- PMID 26414504
- Early repolarization: an evolving concept for the past 70 years.
- Biasco L1, Cristoforetti Y, De Backer O, Castagno D, Giustetto C, Orzan F, Gaita F.
- Journal of cardiovascular medicine (Hagerstown, Md.).J Cardiovasc Med (Hagerstown).2016 Jan;17(1):4-10. doi: 10.2459/JCM.0000000000000276.
- For more than 70 years, early repolarization has been considered to be a common normal variant. In the general population, the prevalence ranges between 5 and 13%, and in athletes, a rising trend is observed from 20 to 90%. Nevertheless, from the latter half of the 1990s, a growing number of case re
- PMID 26090918
- Chemokine ligand 9 modulates cardiac repolarization via Cxcr3 receptor binding.
- Scicluna BP1, Remme CA1, Rivaud M1, Wilde AA1, Bezzina CR2, Verkerk AO3.
- International journal of cardiology.Int J Cardiol.2015 Dec 15;201:49-52. doi: 10.1016/j.ijcard.2015.07.096. Epub 2015 Jul 31.
- PMID 26288327
Japanese Journal
- Brugada症候群,早期再分極症候群,特発性心室細動の遺伝的背景 (特集 循環器疾患と分子遺伝学)
- Mapping and Ablating Ventricular Premature Contractions That Trigger Ventricular Fibrillation: Trigger Elimination and Substrate Modification
- NOGAMI AKIHIKO
- Journal of cardiovascular electrophysiology 26(1), 110-115, 2015-01
- … Ventricular fibrillation (VF) is a malignant arrhythmia, usually initiated by a ventricular premature contraction (VPC) during the vulnerable period of cardiac repolarization. …
- NAID 120005550018
- J-Wave in Patients With Syncope
- Chiba Yuta,Minoura Yoshino,Onishi Yoshimi,Inokuchi Koichiro,Ochi Akinori,Kawasaki Shiro,Onuma Yoshimasa,Munetsugu Yumi,Kikuchi Miwa,Ito Hiroyuki,Onuki Tatsuya,Watanabe Norikazu,Adachi Taro,Asano Taku,Tanno Kaoru,Kobayashi Youichi
- Circulation Journal advpub(0), 2015
- … The presence of J-wave, also known as early repolarization, on electrocardiogram is often seen in the general population, but the relationship between syncope and J-wave is unclear.Methods and Results:After excluding 67 patients with structural heart disease from 326 with syncope, we classified 259 patients according to the presence or absence of J-wave (≥1 mm) in at least 2 inferior or lateral leads. …
- NAID 130005093168
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Related Pictures
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- 英
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- 脱分極
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- Repolarization inhibitors