低蛋白血症
WordNet
- abnormally low level of protein in the blood; can indicate inadequate diet or intestinal or renal disorders
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/12/17 07:50:25」(JST)
[Wiki en表示]
Hypoproteinemia |
Classification and external resources |
ICD-9 |
273.8 |
DiseasesDB |
6534 |
MeSH |
D007019 |
Hypoproteinemia (or hypoproteinaemia) is a condition where there is an abnormally low level of protein in the blood. There are several causes and all result in edema once serum protein levels fall below a certain threshold.
Contents
- 1 Causes
- 2 Pathophysiology
- 3 Management
- 4 External links
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Causes
- Nutritional hypoproteinemia is due to severe limitation of protein intake in the diet. An example of nutritional hypoproteinemia is Kwashiorkor, a type of protein energy malnutrition affecting young children.
- Malabsorption
- Liver disease can also cause hypoproteinemia by decreasing synthesis of plasma proteins like albumin.
- Renal disease like nephrotic syndrome can also result in hypoproteinemia because plasma proteins are lost in the urine.
Pathophysiology
Decreased serum protein decreases the osmotic pressure of the blood, leading to loss of fluid from the intravascular compartment, or the blood vessels, to the interstitial tissues, resulting in edema. This is termed as Hypoproteinemia.
Management
The total serum proteins including albumin levels, which constitutes the major plasma protein in the blood, is measured.
External links
Abnormal clinical and laboratory findings for blood tests (R70–R79, 790)
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Red blood cells |
Size
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- Anisocytosis
- Macrocyte
- Microcyte
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Shape
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- membrane abnormalities: Acanthocyte
- Codocyte
- Ovalocyte
- Spherocyte
- other: Dacrocyte
- Schistocyte
- Degmacyte
- Drepanocyte
- Stomatocyte
- Knizocyte
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Hemoglobinization
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Inclusion bodies
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- developmental organelles (Howell-Jolly body, Basophilic stippling, Pappenheimer bodies, Cabot rings)
- abnormal hemoglobin precipitation (Heinz body)
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Other
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- Rouleaux
- Reticulocyte
- Elevated ESR
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Lymphocytes |
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Small molecules |
Blood sugar
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- Hypoglycemia
- Hyperglycemia
- Prediabetes (Impaired fasting glucose, Impaired glucose tolerance)
- Oxyhyperglycemia
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Nitrogenous
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- Azotemia
- Hyperuricemia
- Hypouricemia
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Proteins |
LFT
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- Elevated transaminases
- Elevated ALP
- Hypoproteinemia (Hypoalbuminemia)
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Other
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- Elevated cardiac markers
- Elevated alpha-fetoprotein
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Minerals |
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Pathogens/sepsis |
- Bacteremia
- Viremia
- Fungemia
- Parasitemia
- Algaemia
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cell/phys (coag, heme, immu, gran), csfs
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rbmg/mogr/tumr/hist, sysi/epon, btst
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drug (B1/2/3+5+6), btst, trns
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noco/acba/cong/tumr, sysi/epon, urte
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proc/itvp, drug (G4B), blte, urte
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UpToDate Contents
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English Journal
- White spots on the mucosal surface of the duodenum in dogs with lymphocytic plasmacytic enteritis.
- Garcia-Sancho M, Sainz A, Villaescusa A, Rodriguez A, Rodriguez-Franco F.SourceDepartment of Animal Medicine and Surgery, College of Veterinary Medicine, Complutense University of Madrid, Avenida Puerta de Hierro s/n, 28040 Madrid, Spain. mercgarc@vet.ucm.es.
- Journal of veterinary science.J Vet Sci.2011 Jun;12(2):165-9.
- Distended lacteals, described as expanded white villi in duodenum, are strongly indicative of primary intestinal lymphangiectasia. In the present study, we evaluated the significance of white spots present in the duodenal mucosa of dogs with lymphocytic plasmacytic enteritis (LPE). Fifty dogs with L
- PMID 21586876
- Dynamics of nutritional status in dying patients with acute cerebral infarction in central China: a preliminary study.
- Zhang H, Shu Y, Zhang J, Tong E.SourceDepartment of Neurology, Zhongnan Hospital of Wuhan University, Wuhan, China.
- Neurological research.Neurol Res.2011 Jun;33(5):503-7.
- BACKGROUND AND AIMS: Stroke is the number one cause of death in China. Although the effective management has reduced the mortality and lengthened survival, little attention has been paid to nutritional issues in patients with stroke in China. This study aimed to assess the premorbid nutrition status
- PMID 21669119
Japanese Journal
- 大腸癌を合併しSMAD4遺伝子異常を確認できた若年性ポリポーシスの1例
- 三宅 清花,上田 渉,有本 雄貴,佐野 弘治,大川 清孝,田村 和朗
- 日本大腸肛門病学会雑誌 64(3), 170-177, 2011
- 症例は40歳代男性.食欲不振と下腿浮腫を自覚し近医を受診した.貧血と低蛋白血症を認め精査のため入院となった.上部消化管内視鏡検査で胃にポリープが密生し胃ポリポーシスと診断した.下部消化管内視鏡検査では盲腸には2型腫瘍と周囲に数個のポリープが見られた.直腸には数十個のポリープを認めた.胃ポリープの生検組織像,十二指腸ポリープと直腸ポリープの内視鏡的粘膜切除の組織像から若年性ポリポーシスと診断できたが …
- NAID 130000662469
- Effects of perfluorooctanoic acid (PFOA) exposure to pregnant mice on reproduction
- YAHIA Doha,EL-NASSER Mahmoud Abd,ABEDEL-LATIF Manal,TSUKUBA Chiaki,YOSHIDA Midori,SATO Itaru,TSUDA Shuji
- Journal of toxicological sciences 35(4), 527-533, 2010-08-01
- … PFOA at 10 mg/kg increased serum enzyme activities (GGT, ALT, AST and ALP) with hypoproteinemia and hypolipidemia. …
- NAID 10026566787
Related Links
- Hypoproteinemia (or "Hypoproteinaemia") is a condition where there is an abnormally low level of protein in the blood. One common cause is due to excess protein in the urine (proteinuria), which can be a medical sign of nephrotic ...
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★リンクテーブル★
[★]
- 英
- hypoproteinemia
- 関
- 低タンパク血症、低アルブミン血症
[show details]
- 基質欠乏:飢餓、吸収不良症候群
- 蛋白合成能低下:肝硬変、低アルブミン血症を来す各種病態(血中蛋白の大半がアルブミン。Alb /TP = 3.5-4.5 / 6.5-8)
- 血液の希釈:妊娠
- サードスペースへの移行:胸水、腹水
- 体外への漏出:
- 蛋白異化亢進:炎症性疾患、悪性疾患、甲状腺機能亢進症
国試