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In vivo xenoestrogenic actions of cadmium and arsenic in anterior pituitary and uterus.

Ronchetti SA1, Novack GV1, Bianchi MS2, Crocco MC1, Duvilanski BH1, Cabilla JP3.
Reproduction (Cambridge, England).Reproduction.2016 Jul;152(1):1-10. doi: 10.1530/REP-16-0115.
Cadmium (Cd) and arsenic (iAs) are toxic metals ubiquitously present in the environment. Both pollutants exert nonmonotonic dose responses, being mostly cytotoxic at high concentrations but mimicking estrogen (E2) effects at low doses. Xenoestrogenic activity of Cd and iAs has been demonstrated in d
PMID 27256631

Multimodal Navigation in Endoscopic Transsphenoidal Resection of Pituitary Tumors using Image-based Vascular and Cranial Nerve Segmentation: A Prospective Validation Study.

Dolati P1, Eichberg D1, Golby A1, Zamani A2, Laws E1.
World neurosurgery.World Neurosurg.2016 Jun 11. pii: S1878-8750(16)30393-X. doi: 10.1016/j.wneu.2016.06.008. [Epub ahead of print]
BACKGROUND: Transsphenoidal surgery (TSS) is the most common approach for the treatment of pituitary tumors. However, misdirection, vascular damage, intraoperative CSF leakage, and optic nerve injuries are all well-known complications, and the risk of adverse events is more likely in less experience
PMID 27302558

Pterostilbene Decreases the Antioxidant Defenses of Aggressive Cancer Cells In Vivo: A Physiological Glucocorticoids- and Nrf2-Dependent Mechanism.

Benlloch M1, Obrador E2, Valles SL2, Rodriguez ML2, Sirerol JA2, Alcácer J3, Pellicer JA2, Salvador R2, Cerdá C4, Sáez GT4,5, Estrela JM2.
Antioxidants & redox signaling.Antioxid Redox Signal.2016 Jun 10;24(17):974-90. doi: 10.1089/ars.2015.6437. Epub 2016 Mar 15.
AIMS: Polyphenolic phytochemicals have anticancer properties. However, in mechanistic studies, lack of correlation with the bioavailable concentrations is a critical issue. Some reports had suggested that these molecules downregulate the stress response, which may affect growth and the antioxidant p
PMID 26651028