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1. 下垂体機能低下症の原因 causes of hypopituitarism
2. 免疫チェックポイント阻害剤による免疫療法に伴う毒性 toxicities associated with checkpoint inhibitor immunotherapy
3. 鞍部腫瘤の原因、症状、および評価 causes presentation and evaluation of sellar masses
4. 進行黒色腫に対する免疫チェックポイント分子阻害による免疫療法 immunotherapy of advanced melanoma with immune checkpoint inhibition
5. 中枢性尿崩症の臨床症状および原因 clinical manifestations and causes of central diabetes insipidus

Effects of chronic growth hormone overexpression on appetite-regulating brain gene expression in coho salmon.

Kim JH1, Leggatt RA1, Chan M1, Volkoff H2, Devlin RH3.
Molecular and cellular endocrinology.Mol Cell Endocrinol.2015 Sep 15;413:178-88. doi: 10.1016/j.mce.2015.06.024. Epub 2015 Jun 26.
Organisms must carefully regulate energy intake and expenditure to balance growth and trade-offs with other physiological processes. This regulation is influenced by key pathways controlling appetite, feeding behaviour and energy homeostasis. Growth hormone (GH) transgenesis provides a model where f
PMID 26123591

Intrapancreatic Accessory Spleen Mimicking Neuroendocrine Tumor on 68Ga-DOTATATE PET/CT.

Bhure U1, Metzger J, Keller FA, Zander A, Lago MP, Herring K, Strobel K.
Clinical nuclear medicine.Clin Nucl Med.2015 Sep;40(9):744-5. doi: 10.1097/RLU.0000000000000863.
Besides well-known physiologic uptake of Ga-DOTATATE in spleen, pituitary gland, pancreatic head, adrenals, kidney, and urinary bladder, sometimes unusual areas of uptake are found. We report a case of a 53-year-old woman who had vague pain in abdomen for which abdominal CT was done showing a contra
PMID 26053721

Transcript levels of the soluble sperm factor protein phospholipase C zeta 1 (PLCζ1) increase through induced spermatogenesis in European eel.

Morini M1, Peñaranda DS1, Vílchez MC1, Gallego V1, Nourizadeh-Lillabadi R2, Asturiano JF1, Weltzien FA2, Pérez L3.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.Comp Biochem Physiol A Mol Integr Physiol.2015 Sep;187:168-76. doi: 10.1016/j.cbpa.2015.05.028. Epub 2015 Jun 4.
Activation at fertilization of the vertebrate egg is triggered by Ca(2+) waves. Recent studies suggest the phospholipase C zeta (PLCζ), a sperm-specific protein, triggers egg activation by an IP3-mediated Ca(2+) release and allow Ca(2+) waves at fertilization. In the present study we cloned, charac
PMID 26051612