WordNet

an agent who handles something or someone; "the senators campaign handlers"
a maker (and seller) of candles and soap and oils and paints
a retail dealer in provisions and supplies
a beggar who approaches strangers asking for money
a dealer in sails and ropes and other supplies for sailing ships
a dealer in equipment and supplies for ships
one who deals in wax candles
show and train; "The prize-winning poodle was handled by Mrs. Priscilla Prescott"
the appendage to an object that is designed to be held in order to use or move it; "he grabbed the hammer by the handle"; "it was an old briefcase but it still had a good grip" (同)grip, handgrip, hold
touch, lift, or hold with the hands; "Dont handle the merchandise" (同)palm

PrepTutorEJDIC

(人・物を)扱う人 / 犬(馬など)を品評会に出す人 / (ボクシングの)介添え人
ろうそく製造販売人 / 雑貨商
物乞い,こじき
『取って』,柄,ハンドル / 手がかり,きっかけ / 《話》(sirなどの)肩書き / …‘に'『手で触れる』;手で持つ / 〈材料・道具など〉‘を'手で扱う / 〈人・動物など〉を『扱い』,統制する / 〈問題など〉‘を'扱う,処理する,〈曲など〉‘を'弾きこなす / 〈商品〉‘を'扱う,商う / 〈自動車などが〉扱われる,操縦される(できる)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/01/24 19:14:45」(JST)

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Look up handler in Wiktionary, the free dictionary.

Handler may refer to:

People

Handler - Downfield, offensive player in the sport of Ultimate. Usually a player with stronger throws.
Animal handler, person who conducts animal training or is a wrangler (profession)
Handler, a coach, sports agent of a sports player, or entertainer promoter
Agent handler, person who manages a spy
Baggage handler, a person who loads and unloads baggage and other cargo for transport via aircraft
Mail handler, a postal worker
Aircraft Handler, a branch of the Fleet Air Arm / Royal Navy
Garter handler, an old term for a pimp
Political Handler, an advisor and supporter of a politician

Computing

Handler, an asynchronous callback subroutine in computing
Handler, a particular class of service process in DNIX
A20 handler, the IBM PC memory manager software controlling access to the High Memory Area
Event handler, a routine for processing a programming event
Interrupt handler, a routine for processing CPU interrupts
Signal handler, a routine for handling signals sent to a process
Exception handler, a routine for handling software exceptions

Machines

Air handler, a device used as part of an HVAC (Heating, Ventilating, and Air Conditioning) system
Handler, a robotic device used to automatically place a device under test into an automatic test equipment system
Seismic Handler, an interactive analysis program for preferably continuous waveform data
Telescopic handler, a machine widely used in agriculture and industry

Arts and entertainment

Handler (play), by Robert Schenkkan
The Handler, the third CD from American singer Har Mar Superstar
Handler, a character class in Dragonlance

Persons named Handler

Handler is the surname of:

Carole Handler, American Intellectual Property attorney
Chelsea Handler, American stand-up comedian
Daniel Handler, American author, screenwriter, and accordionist
Evan Handler, American actor
Evelyn Handler, 17th president of the University of New Hampshire
Ferdinánd Nándor Handler (1836-1888), Hungarian architect
Phil Handler, football player and coach who spent his entire professional career in the city of Chicago
Rebecca Handler, American/Japanese actress
Ruth Handler, American businesswoman and the president of the toy manufacturer Mattel
Howard Handler, Policy Analyst and Political Strategist

UpToDate Contents

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5. 患者情報：A型肝炎（詳細） hepatitis a beyond the basics

English Journal

Advances in artificial olfaction: Sensors and applications.

Gutiérrez J1, Horrillo MC2.Author information 1Grupo de I+D en Sensores (GRIDSEN), Instituto de Tecnologías Electrónicas y de la Información (ITEFI), CSIC, C/Serrano 144, 28006 Madrid, Spain.2Grupo de I+D en Sensores (GRIDSEN), Instituto de Tecnologías Electrónicas y de la Información (ITEFI), CSIC, C/Serrano 144, 28006 Madrid, Spain. Electronic address: carmen.horrillo.guemes@csic.es.AbstractThe artificial olfaction, based on electronic systems (electronic noses), includes three basic functions that operate on an odorant: a sample handler, an array of gas sensors, and a signal-processing method. The response of these artificial systems can be the identity of the odorant, an estimate concentration of the odorant, or characteristic properties of the odour as might be perceived by a human. These electronic noses are bio inspired instruments that mimic the sense of smell. The complexity of most odorants makes characterisation difficult with conventional analysis techniques, such as gas chromatography. Sensory analysis by a panel of experts is a costly process since it requires trained people who can work for only relatively short periods of time. The electronic noses are easy to build, provide short analysis times, in real time and on-line, and show high sensitivity and selectivity to the tested odorants. These systems are non-destructive techniques used to characterise odorants in diverse applications linked with the quality of life such as: control of foods, environmental quality, citizen security or clinical diagnostics. However, there is much research still to be done especially with regard to new materials and sensors technology, data processing, interpretation and validation of results. This work examines the main features of modern electronic noses and their most important applications in the environmental, and security fields. The above mentioned main components of an electronic nose (sample handling system, more advanced materials and methods for sensing, and data processing system) are described. Finally, some interesting remarks concerning the strengths and weaknesses of electronic noses in the different applications are also mentioned.
Talanta.Talanta.2014 Jun 15;124C:95-105. doi: 10.1016/j.talanta.2014.02.016. Epub 2014 Feb 25.
The artificial olfaction, based on electronic systems (electronic noses), includes three basic functions that operate on an odorant: a sample handler, an array of gas sensors, and a signal-processing method. The response of these artificial systems can be the identity of the odorant, an estimate con
PMID 24767451

The fusions of elastin-like polypeptides and xylanase self-assembled into insoluble active xylanase particles.

Li C1, Zhang G2.Author information 1Department of Biotechnology and Bioengineering, Huaqiao University, Xiamen 361021, Fujian, PR China.2Department of Biotechnology and Bioengineering, Huaqiao University, Xiamen 361021, Fujian, PR China. Electronic address: zhgyghh@hqu.edu.cn.AbstractWe fused the genes of elastin-like polypeptides (ELPs) and xylanase and then expressed them in Escherichia coli. Unexpectedly, the fusion proteins self-assembled into insoluble active particles as the ELPs underwent a hardly reversible phase transition. The specific activity of the particles was 92% of the native counterparts, which means it can act as a pull-down handler for converting soluble proteins into active aggregates. We evaluated the characterizations of the insoluble active xylanase particles in detail and the results were encouraging. The pH optimum (6.0) of the particles was the same as the free one, but the optimum pH range was 5-7, while the free xylanase was 6-7. The free xylanase had an optimum temperature of 50°C, whereas the insoluble active xylanase particles shifted to 70°C. The pH stability, thermostability and storage stability of the xylanase particles increased significantly when compared with the free xylanase. We also observed an increase of the Km values of the free xylanase from 0.374gL(-1) to 0.980gL(-1) at the insoluble state. The considerable higher activity and stability of the xylanase particles were much like immobilized xylanases and could be valuable for its industrial application.
Journal of biotechnology.J Biotechnol.2014 May 10;177:60-6. doi: 10.1016/j.jbiotec.2014.02.020. Epub 2014 Mar 5.
We fused the genes of elastin-like polypeptides (ELPs) and xylanase and then expressed them in Escherichia coli. Unexpectedly, the fusion proteins self-assembled into insoluble active particles as the ELPs underwent a hardly reversible phase transition. The specific activity of the particles was 92%
PMID 24613298

Molecular sub-group-specific immunophenotypic changes are associated with outcome in recurrent posterior fossa ependymoma.

Hoffman LM1, Donson AM, Nakachi I, Griesinger AM, Birks DK, Amani V, Hemenway MS, Liu AK, Wang M, Hankinson TC, Handler MH, Foreman NK.Author information 1Department of Pediatrics, University of Colorado Denver, 12800 East 19th Avenue, Aurora, CO, 80045, USA, lindsey.hoffman@childrenscolorado.org.AbstractBetter understanding of ependymoma (EPN) biology at relapse is needed to improve therapy at this critical event. Convincing data exist defining transcriptionally distinct posterior fossa (PF) sub-groups A and B at diagnosis. The clinical and biological consequence of these sub-groups at recurrence has not yet been defined. Genome and transcriptome microarray profiles and clinical variables of matched primary and first recurrent PF EPN pairs were used to identify biologically distinct patterns of progression between EPN sub-groups at recurrence. Key findings were validated by histology and immune function assays. Transcriptomic profiles were partially conserved at recurrence. However, 4 of 14 paired samples changed sub-groups at recurrence, and significant sub-group-specific transcriptomic changes between primary and recurrent tumors were identified, which were predominantly immune-related. Further examination revealed that Group A primary tumors harbor an immune gene signature and cellular functionality consistent with an immunosuppressive phenotype associated with tissue remodeling and wound healing. Conversely, Group B tumors develop an adaptive, antigen-specific immune response signature and increased T-cell infiltration at recurrence. Clinical distinctions between sub-groups become more apparent after first recurrence. Group A tumors were more often sub-totally resected and had a significantly shorter time to subsequent progression and worse overall survival. Minimal tumor-specific genomic changes were observed for either PF Groups A or B at recurrence. Molecular sub-groups of PF EPN convey distinct immunobiologic signatures at diagnosis and recurrence, providing potential biologic rationale to their disparate clinical outcomes. Immunotherapeutic approaches may be warranted, particularly in Group A PF EPN.
Acta neuropathologica.Acta Neuropathol.2014 May;127(5):731-45. doi: 10.1007/s00401-013-1212-8. Epub 2013 Nov 17.
Better understanding of ependymoma (EPN) biology at relapse is needed to improve therapy at this critical event. Convincing data exist defining transcriptionally distinct posterior fossa (PF) sub-groups A and B at diagnosis. The clinical and biological consequence of these sub-groups at recurrence h
PMID 24240813

Japanese Journal

過去に大麻取扱者であった者が産業用大麻を所持したところ、大麻を不法所持したと判断された事例 : 東京地裁平成25年4月24日判決(公刊物未掲載)

青山社会科学紀要 = Aoyama journal of social sciences : economics, law and business 44(1), 75-99, 2015-09
NAID 40020612070

Dalvik Bytecode Acceleration Using Fetch/Decode Hardware Extension (Preprint)

情報処理学会論文誌 56(2), 2015-02-15
NAID 110009877386

仮想化機構を利用する大規模サービス基盤のためのストレージ設定高速化機構

情報処理学会論文誌 56(2), 503-515, 2015-02-15
NAID 110009877366

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