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1. 甲状腺結節および非髄様甲状腺癌におけるオンコジーンおよび腫瘍抑制遺伝子 oncogenes and tumor suppressor genes in thyroid nodules and nonmedullary thyroid cancer
2. 甲状腺ホルモンの合成および生理 thyroid hormone synthesis and physiology
3. 成人におけるセリアック病の病因、疫学、および臨床症状 pathogenesis epidemiology and clinical manifestations of celiac disease in adults
4. 癌患者における経口栄養補給および経口／経腸栄養補給の役割 the role of parenteral and enteral oral nutritional support in patients with cancer
5. 重症患者における栄養補給：経腸栄養 nutrition support in critically ill patients enteral nutrition

Role of DNA conformation & energetic insights in Msx-1-DNA recognition as revealed by molecular dynamics studies on specific and nonspecific complexes.

Kachhap S1, Singh B.
Journal of biomolecular structure & dynamics.J Biomol Struct Dyn.2015 Oct;33(10):2069-82. doi: 10.1080/07391102.2014.995709. Epub 2015 Jan 12.
In most of homeodomain-DNA complexes, glutamine or lysine is present at 50th position and interacts with 5th and 6th nucleotide of core recognition region. Molecular dynamics simulations of Msx-1-DNA complex (Q50-TG) and its variant complexes, that is specific (Q50K-CC), nonspecific (Q50-CC) having
PMID 25484111

The importance of glutamine 294 that affects the ribonuclease H activity of the reverse transcriptase of HIV-2 to viral replication.

Herzig E1, Hizi A2.
Virology.Virology.2015 Sep;483:13-20. doi: 10.1016/j.virol.2015.04.018. Epub 2015 May 15.
Most currently-used antiretroviral drugs inhibit the reverse-transcriptase (RT) of HIV. The differences between HIV-1 and HIV-2 RTs explain why some of the anti-HIV-1 drugs are not effective against HIV-2. One major difference between the two HIV RTs is the low ribonuclease H (RNase H) activity of H
PMID 25965791

Role of the salt bridge between glutamate 546 and arginine 907 in preservation of autoinhibited form of Apaf-1.

Shakeri R1, Hosseinkhani S2, Los MJ3, Davoodi J1, Jain MV4, Pobuda AC5, Rafat M6, Ardestani SK7.
International journal of biological macromolecules.Int J Biol Macromol.2015 Aug 13. pii: S0141-8130(15)00562-0. doi: 10.1016/j.ijbiomac.2015.08.027. [Epub ahead of print]
Apaf-1, the key element of apoptotic mitochondrial pathway, normally exists in an auto-inhibited form inside the cytosol. WRD-domain of Apaf-1 has a critical role in the preservation of auto-inhibited form; however the underlying mechanism is unclear. It seems the salt bridges between WRD and NOD do
PMID 26277751