WordNet
- the act of tolerating something
- the power or capacity of an organism to tolerate unfavorable environmental conditions
- willingness to recognize and respect the beliefs or practices of others
- a monosaccharide sugar that has several forms; an important source of physiological energy
PrepTutorEJDIC
- (自分と異なる他人の意見・行動などを許す)寛大,寛容・我慢(がまん),忍耐力 / (薬品・毒物などに対する)耐性,抗毒性 / 公差,許容誤差
- ブドウ糖
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/03/10 09:52:04」(JST)
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Impaired glucose tolerance |
Classification and external resources |
ICD-10 |
R73.0 |
ICD-9 |
790.21 |
MeSH |
D018149 |
Impaired glucose tolerance (IGT) is a pre-diabetic state of hyperglycemia that is associated with insulin resistance and increased risk of cardiovascular pathology. IGT may precede type 2 diabetes mellitus by many years. IGT is also a risk factor for mortality.[1]
Contents
- 1 Criteria
- 2 Treatment
- 3 See also
- 4 References
- 5 Further reading
Criteria[edit]
According to the criteria of the World Health Organization and the American Diabetes Association, impaired glucose tolerance is defined as:[2][3][4]
- two-hour glucose levels of 140 to 199 mg per dL (7.8 to 11.0 mmol) on the 75-g oral glucose tolerance test. A patient is said to be under the condition of IGT when he/she has an intermediately raised glucose level after 2 hours, but less than would qualify for type 2 diabetes mellitus. The fasting glucose may be either normal or mildly elevated.
From 10 to 15 percent of adults in the United States have impaired glucose tolerance or impaired fasting glucose.[5]
Treatment[edit]
Main article: Prevention of diabetes mellitus type 2
The risk of progression to diabetes and development of cardiovascular disease is greater than for impaired fasting glucose.[6]
Although some drugs can delay the onset of diabetes, lifestyle modifications play a greater role in the prevention of diabetes.[5][7] Patients identified as having an IGT should exercise regularly, lose 5 to 7 percent of body weight, and limit intake of (at least) sugar and highly processed carbohydrates.[5] America is known to have a higher percentage of diabetes due to the average intake of sugar and high carbohydrate food consumed by the general population.
See also[edit]
- Glucose tolerance test
- Impaired fasting glucose
References[edit]
- ^ Barr EL, Zimmet PZ, Welborn TA, et al. (2007). "Risk of cardiovascular and all-cause mortality in individuals with diabetes mellitus, impaired fasting glucose, and impaired glucose tolerance: the Australian Diabetes, Obesity, and Lifestyle Study (AusDiab)". Circulation 116 (2): 151–7. doi:10.1161/CIRCULATIONAHA.106.685628. PMID 17576864.
- ^ .World Health Organization. "Definition, diagnosis and classification of diabetes mellitus and its complications: Report of a WHO Consultation. Part 1. Diagnosis and classification of diabetes mellitus". Retrieved 2007-05-29.
- ^ American Diabetes, Association (2005). "Diagnosis and classification of diabetes mellitus". Diabetes Care. 28 Suppl 1: S37–42. PMID 15618111.
- ^ http://www.diabetes.co.uk/impaired-glucose-tolerance.html
- ^ a b c Shobha S. Rao, Phillip Disraeli, Tamara McGregor (15 April 2004). "Impaired Glucose Tolerance and Impaired Fasting Glucose". American Family Physician 69 (8): 1961.
- ^ Oxford Handbook of Clinical Medicine, 7th Ed., Longmore, Wilkinson, Turmezei and Cheung. Oxford University Press 2007.
- ^ Raina Elley C, Kenealy T (December 2008). "Lifestyle interventions reduced the long-term risk of diabetes in adults with impaired glucose tolerance". Evid Based Med 13 (6): 173. doi:10.1136/ebm.13.6.173. PMID 19043031.
Further reading[edit]
- Melanie J Davies, I Peter Gray (3 February 1996). "Impaired glucose tolerance". British Medical Journal 312 (7026): 264–265. PMC 2349870. PMID 8611769. - Editorial review
- Nathan, DM; Davidson, MB; DeFronzo, RA; Heine, RJ; Henry, RR; Pratley, R; Zinman, B; American Diabetes, Association (March 2007). "Impaired fasting glucose and impaired glucose tolerance: implications for care.". Diabetes care 30 (3): 753–9. doi:10.2337/dc07-9920. PMID 17327355.
Abnormal clinical and laboratory findings for blood tests (R70–R79, 790)
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Red blood cells |
Size
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- Anisocytosis
- Macrocyte
- Microcyte
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Shape
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- membrane abnormalities: Acanthocyte
- Codocyte
- Ovalocyte
- Spherocyte
- other: Dacrocyte
- Echinocyte
- Schistocyte
- Degmacyte
- Drepanocyte
- Stomatocyte
- Knizocyte
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Hemoglobinization
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Inclusion bodies
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- developmental organelles (Howell-Jolly body, Basophilic stippling, Pappenheimer bodies, Cabot rings)
- abnormal hemoglobin precipitation (Heinz body)
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Other
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- Rouleaux
- Reticulocyte
- Elevated ESR
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Lymphocytes |
|
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Small molecules |
Blood sugar
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- Hypoglycemia
- Hyperglycemia
- Prediabetes (Impaired fasting glucose, Impaired glucose tolerance)
- Oxyhyperglycemia
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Nitrogenous
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- Azotemia
- Hyperuricemia
- Hypouricemia
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Proteins |
LFT
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- Elevated transaminases
- Elevated ALP
- Hypoproteinemia (Hypoalbuminemia)
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Other
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- Elevated cardiac markers
- Elevated alpha-fetoprotein
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Minerals |
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Pathogens/sepsis |
- Bacteremia
- Viremia
- Fungemia
- Parasitemia
- Algaemia
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cell/phys (coag, heme, immu, gran), csfs
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rbmg/mogr/tumr/hist, sysi/epon, btst
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drug (B1/2/3+5+6), btst, trns
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noco/acba/cong/tumr, sysi/epon, urte
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proc/itvp, drug (G4B), blte, urte
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Diabetes (E10–E14, 250)
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Types of diabetes |
- Prediabetes
- Impaired fasting glucose
- Impaired glucose tolerance
- Insulin resistance
- Conventional insulinotherapy
- Type 1
- LADA
- Type 2
- KPD
- MODY
- NDM
- Glossary of diabetes
- Diabetes and pregnancy: Gestational diabetes
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Blood tests |
- Blood sugar
- Glycosylated hemoglobin
- Glucose tolerance test
- Fructosamine
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Diabetes management |
- Diabetic diet
- Anti-diabetic drugs
- Oral anti-diabetic drugs and insulin analogs
- Insulin therapy
- Intensive insulinotherapy
- Pulsatile insulin
- Cure
- Embryonic stem cells
- Gastric bypass surgery
- Artificial pancreas
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Complications/prognosis |
- Diabetic comas
- Diabetic hypoglycemia
- Diabetic ketoacidosis
- Hyperglycemic hyperosmolar state
- Diabetic angiopathy
- Diabetic foot
- ulcer
- Neuropathic arthropathy
- Diabetic myonecrosis
- Diabetic nephropathy
- Diabetic neuropathy
- Diabetic retinopathy
- Diabetic cardiomyopathy
- Diabetic dermadrome
- Diabetic dermopathy
- Diabetic bulla
- Diabetic cheiroarthropathy
- Neuropathic ulcer
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Other |
- Hypoglycemia/Hyperglycemia
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noco (d)/cong/tumr, sysi/epon
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proc, drug (A10/H1/H2/H3/H5)
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UpToDate Contents
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English Journal
- In vitro digestibility and in vivo glucose response of native and physically modified rice starches varying amylose contents.
- Van Hung P1, Chau HT2, Phi NT3.
- Food chemistry.Food Chem.2016 Jan 15;191:74-80. doi: 10.1016/j.foodchem.2015.02.118. Epub 2015 Feb 28.
- The native and physically modified rice starches with varying amylose contents were subjected to investigate the in vitro digestibility and the in vivo glucose tolerance in mice. The amylose and resistant starch (RS) contents of five native rice starches ranged in 4.7-30.6% and 6.3-11.8%, respective
- PMID 26258704
- Energy Metabolism, Adult Neurogenesis and their Possible Roles in Alzheimer's Disease: A Brief Overview.
- Sun P, Hua Q, Schmitt AG1.
- Current topics in medicinal chemistry.Curr Top Med Chem.2016;16(5):493-502.
- Alzheimer's disease (AD) is the most prevalent human neurodegenerative disease. Disturbances of brain glucose uptake, glucose tolerance, glucose utilization and of the insulin/insulin receptor signaling cascade are thought to be key features of the pathophysiology of AD. Changes in energy homeostasi
- PMID 26268335
Japanese Journal
- 健常大学生における豆乳・納豆のセカンドミール血糖上昇抑制効果
- 必須元素としてのクロム (特集 日本食品標準成分表(2010)に新たに収載されたビタミン・ミネラルの活用と課題)
Related Links
- Impaired glucose tolerance (IGT) is a pre-diabetic state of hyperglycemia that is associated with insulin resistance and increased risk of cardiovascular pathology . IGT may precede type 2 diabetes mellitus by many years. IGT is also a risk ...
- A glucose tolerance test is a medical test in which glucose is given and blood samples taken afterward to determine how quickly it is cleared from the blood. The test is usually used to test for diabetes, insulin resistance, and sometimes reactive ...
Related Pictures
★リンクテーブル★
[★]
- 英
- glucose tolerance
- 関
- 耐糖性、耐糖能、糖耐性
[★]
- 英
- glucose tolerance
- 関
- 耐糖、耐糖性、耐糖能
[★]
- 英
- glucose tolerance
- 関
- 耐糖、耐糖性、糖耐性
[★]
耐糖能障害 IGT、glucose intolerance
[★]
経口ブドウ糖負荷試験
[★]
経口ブドウ糖負荷試験
[★]
耐性
- 関
- self-tolerance