WordNet
- see for the first time; make a discovery; "Who discovered the North Pole?"
- make a discovery, make a new finding; "Roentgen discovered X-rays"; "Physicists believe they found a new elementary particle" (同)find
- make a discovery; "She found that he had lied to her"; "The story is false, so far as I can discover" (同)find
- the act of discovering something (同)find, uncovering
- a productive insight (同)breakthrough, find
- (law) compulsory pretrial disclosure of documents relevant to a case; enables one side in a litigation to elicit information from the other side concerning the facts in the case
- something that is discovered
- use recreational drugs (同)do drugs
- administer a drug to; "They drugged the kidnapped tourist" (同)dose
- a substance that is used as a medicine or narcotic
- the branch of genetics that studies organisms in terms of their genomes (their full DNA sequences)
PrepTutorEJDIC
- 〈今まで知らなかった物・場所〉‘を'『発見する』,見付ける / 〈今まで知らなかった事〉‘を'発見する,悟る
- 〈U〉『発見』;〈C〉発見した物(事)
- 『薬』,薬品,薬剤 / 『麻薬』,麻酔剤 / 〈人〉‘に'薬(特に麻酔剤)を与える / 〈飲食物〉‘に'(麻酔薬・毒薬などの)薬を混ぜる
UpToDate Contents
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English Journal
- Towards pathway-centric cancer therapies via pharmacogenomic profiling analysis of ERK signalling pathway.
- Wang H1, Zheng X, Fei T, Wang J, Li X, Liu Y, Zhang F.
- Clinical and translational medicine.Clin Transl Med.2015 Dec;4(1):66. doi: 10.1186/s40169-015-0066-1. Epub 2015 Jul 28.
- BACKGROUND: Genomic heterogeneity in human cancers complicates gene-centric personalized medicine. Malignant tumors often share a core group of pathways that are perturbed by diverse genetic mutations. Therefore, one possible solution to overcome the heterogeneity challenge is a shift from gene-cent
- PMID 26220863
- A comprehensive glycome profiling of Huntington's disease transgenic mice.
- Gizaw ST1, Koda T2, Amano M1, Kamimura K2, Ohashi T3, Hinou H3, Nishimura S4.
- Biochimica et biophysica acta.Biochim Biophys Acta.2015 Sep;1850(9):1704-18. doi: 10.1016/j.bbagen.2015.04.006. Epub 2015 Apr 20.
- BACKGROUND: Huntington's disease (HD) is an autosomal, dominantly inherited and progressive neurodegenerative disease, nosologically classified as the presence of intranuclear inclusion bodies and the loss of GABA-containing neurons in the neostriatum and subsequently in the cerebellar cortex. Abnor
- PMID 25907331
- A Plasmid-Borne System To Assess the Excision and Integration of Staphylococcal Cassette Chromosome mec Mediated by CcrA and CcrB.
- Wang L1, Ahmed MH2, Safo MK2, Archer GL3.
- Journal of bacteriology.J Bacteriol.2015 Sep 1;197(17):2754-61. doi: 10.1128/JB.00078-15. Epub 2015 Jun 8.
- Resistance to methicillin and other β-lactam antibiotics in staphylococci is due to mecA, which is carried on a genomic island, staphylococcal cassette chromosome mec (SCCmec). The chromosomal excision and integration of SCCmec are mediated by the site-specific recombinase CcrAB or CcrC, encoded wi
- PMID 26055110
Japanese Journal
- 斎藤 嘉朗,佐井 君江,鹿庭 なほ子,田島 陽子,石川 将己,最上(西巻) 知子,前川 京子
- YAKUGAKU ZASSHI 133(12), 1373-1379, 2013
- … Biomarkers are useful tools as indicators/predictors of disease severity and drug responsiveness, and thus, are expected to make drug development more efficient and to accelerate proper use of approved drugs. … Many academic achievements on biomarkers have been reported, but only several biomarkers are used in drug development and clinical settings. …
- NAID 130003382293
- 薬事規制当局側からの革新的drug delivery systems (DDS)への期待
- 森 和彦
- YAKUGAKU ZASSHI 133(1), 73-80, 2013
- … These responsibilities are essential missions of the MHLW/PMDA, although restrictions on drug use or development might be considered to be purely regulatory matters. … In the genomic drug discovery era of the 21st century, it is expected that new, innovative drugs will be developed, although the reality can be slightly disturbing. …
- NAID 130003361882
- Predictive genomic biomarkers for drug-induced nephrotoxicity in mice
- Kondo Chiaki,Aoki Miwa,Yamamoto Emi [他],TONOMURA Yutaka,IKEDA Minoru,KANETO Masako,YAMATE Jyoji,TORII Mikinori,UEHARA Takeki
- Journal of toxicological sciences 37(4), 723-737, 2012-08-01
- NAID 10030502220
Related Links
- Forerunner Pharma Research (FPR) is a Tokyo-based biopharmaceutical venture focusing antibody drug development for cancer diagnostics and therapeutics. ... Exploring the Seeds of Innovative Drug Discovery Through Open ...
- Preface. Chapter 1: Introduction: Genomics and Personalized Medicine (Dimitri Semizarov). 1.1. Fundamentals of genomics. 1.2. The concept of personalized medicine. 1.3. Genomics technologies in drug discovery. 1.4. Scope of ...
★リンクテーブル★
[★]
- 英
- genomic drug discovery
[★]
- 関
- discovery、find、finding
[★]
- 関
- discover、find、finding
[★]
- 関
- genome、genomically
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- 関
- drug development
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- 同
- drugs