WordNet

of or relating to the mind; "mental powers"; "mental development"; "mental hygiene"
affected by a disorder of the mind; "a mental patient"; "mental illness"
involving the mind or an intellectual process; "mental images of happy times"; "mental calculations"; "in a terrible mental state"; "mental suffering"; "free from mental defects"
of or relating to the chin- or liplike structure in insects and certain mollusks
the extent to which something is delayed or held back
lack of normal development of intellectual capacities (同)mental_retardation, backwardness, slowness, subnormality
vulnerably delicate; "she has the fragile beauty of youth"
any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
the 24th letter of the Roman alphabet (同)x, ex

PrepTutorEJDIC

『精神の』,心の / 頭脳の,知能の / 《名詞の前にのみ用いて》精神病の / 《名詞の前にのみ用いて》頭の中で行う / 《英話》《補語にのみ用いて》頭のおかしい,気がふれた
〈U〉遅延,遅滞 / 〈C〉遅らせるもの;妨害物 / 〈U〉〈C〉知能(学業など)の遅れ
『壊れやすい』,もろい / (体質が)虚弱な(weak);《おどけて》調子が悪い / (幸福などが)はかない
蛋白(たんばく)質
Christ / Christian

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1. 脆弱Ｘ症候群の出生前スクリーニングおよび診断 prenatal screening and diagnosis for fragile x syndrome
2. 脆弱X症候群：小児および思春期における臨床的特徴および診断 fragile x syndrome clinical features and diagnosis in children and adolescents
3. 脆弱X症候群：小児および思春期におけるマネージメント fragile x syndrome management in children and adolescents
4. 知的障害（精神遅滞）をもつ成人のプライマリケア primary care of the adult with intellectual disability mental retardation
5. 脊髄小脳変性症 the spinocerebellar ataxias

Abnormal neuronal morphology and neurochemistry in the auditory brainstem of Fmr1 knockout rats.

Ruby K1, Falvey K2, Kulesza RJ3.
Neuroscience.Neuroscience.2015 Sep 10;303:285-98. doi: 10.1016/j.neuroscience.2015.06.061. Epub 2015 Jul 9.
Fragile X syndrome (FXS) is an inherited neurodevelopmental disorder affecting nearly one in 5000 newborn males and is a leading genetic cause of autism spectrum disorder. In addition to developmental delays and intellectual impairment, FXS is characterized by seizures, attention deficit, and hypers
PMID 26166728

The potential role of melatonin on sleep deprivation-induced cognitive impairments: Implication of FMRP on cognitive function.

Kwon KJ1, Lee EJ2, Kim MK2, Jeon SJ3, Choi YY4, Shin CY2, Han SH5.
Neuroscience.Neuroscience.2015 Aug 20;301:403-14. doi: 10.1016/j.neuroscience.2015.05.079. Epub 2015 Jun 3.
While prolonged sleep deprivation (SD) could lead to profound negative health consequences, such as impairments in vital biological functions of immunity and cognition, melatonin possesses powerful ameliorating effects against those harmful insults. Melatonin has strong antioxidant and anti-inflamma
PMID 26047724

The FMRP/GRK4 mRNA interaction uncovers a new mode of binding of the Fragile X mental retardation protein in cerebellum.

Maurin T1, Melko M1, Abekhoukh S1, Khalfallah O1, Davidovic L1, Jarjat M1, D'Antoni S2, Catania MV3, Moine H4, Bechara E1, Bardoni B5.
Nucleic acids research.Nucleic Acids Res.2015 Aug 6. pii: gkv801. [Epub ahead of print]
Fragile X syndrome (FXS), the most common form of inherited intellectual disability, is caused by the silencing of the FMR1 gene encoding an RNA-binding protein (FMRP) mainly involved in translational control. We characterized the interaction between FMRP and the mRNA of GRK4, a member of the guanin
PMID 26250109

Novel Etiological and Therapeutic Strategies for Neurodiseases : RNA Editing Enzyme Abnormality in Sporadic Amyotrophic Lateral Sclerosis

Novel Etiological and Therapeutic Strategies for Neurodiseases: RNA Editing Enzyme Abnormality in Sporadic Amyotrophic Lateral Sclerosis

Hideyama Takuto,Yamashita Takenari,Nishimoto Yoshinori [他],Suzuki Takeshi,Kwak Shin
Journal of Pharmacological Sciences 113(1), 9-13, 2010
… We found that cytoplasmic fragile X mental retardation protein interacting protein 2 (CYFIP2) mRNA had an ADAR2-mediated editing position using RNA interference knockdown. …
NAID 130000253396