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Oh H1, Li T2, An J3.
Chemistry (Weinheim an der Bergstrasse, Germany).Chemistry.2015 Sep 25. doi: 10.1002/chem.201501560. [Epub ahead of print]
The drug uptake and release properties of a series of biomolecule-based metal-organic frameworks (bMOF-1, bMOF-4, bMOF-100, and bMOF-102) have been studied. The bMOFs were loaded with the small molecule etilefrine hydrochloride and release profiles were collected in both Nanopure water and simulated
PMID 26403522

Evaluation of cardiovascular changes in dogs administered three positive controls using jacketed external telemetry-blood pressure (JET-BP).

Kremer JJ1, Bills AJ2, Hanke NJ2, Chen H2, Meier WA2, Osinski MA2, Foley CM2.
Journal of pharmacological and toxicological methods.J Pharmacol Toxicol Methods.2015 Sep-Oct;75:27-37. doi: 10.1016/j.vascn.2015.05.008. Epub 2015 May 20.
INTRODUCTION: Nonclinical safety studies are increasingly incorporating cardiac safety endpoints to discover potential cardiovascular liabilities. This trend for more thorough cardiovascular nonclinical safety evaluation is prudent given the high attrition rate of potential therapeutics due to unexp
PMID 26001324

[No authors listed]
Prescrire international.Prescrire Int.2015 Jul;24(162):184.
The French Health Products Agency concluded that etilefrine and heptaminol have an unfavourable harm-benefit balance, and also placed restrictions on the use of midodrine.
PMID 26240886

内田豊昭,小俣二也,小柴健
泌尿器科紀要 32(12), 1879-1882, 1986-12
… 勃起状態に対して塩酸エチレフリン1 mgないし2 mgを局注し,勃起状態の消退が得られた.2)塩酸エチレフリンの使用量は塩酸パパベリン40 mg局注の場合2 mgが適当量と思われた.3)塩酸エチレフリン局注後,全例とも特に副作用は認められなかったIntracavernous injection of etilefrine hydrochloride (1 or 2 mg) was performed on four patients with fully erected penis after intracavernous injection of 40 mg of papaverine hydrochloride. …
NAID 120002159429