WordNet
- come on stage
- to come or go into; "the boat entered an area of shallow marshes" (同)come_in, get_into, get_in, go_into, go in, move into
- become a participant; be involved in; "enter a race"; "enter an agreement"; "enter a drug treatment program"; "enter negotiations" (同)participate
- a thin layer covering something; "a second coat of paint" (同)coat
- a decorative texture or appearance of a surface (or the substance that gives it that appearance); "the boat had a metallic finish"; "he applied a coat of a clear finish"; "when the finish is too thin it is difficult to apply evenly" (同)finish, finishing
- a heavy fabric suitable for coats
- omnivorous mammal of Central America and South America (同)coati-mondi, coati-mundi, coon cat, Nasua narica
- of or relating to the enteron (同)enteral
PrepTutorEJDIC
- …‘に'『入る』,入り込む / 〈弾丸などが〉…‘を'突き通す,‘に'入り込む(penetrate) / …‘の'『一員となる』,‘に'入る;…‘に'参加する / (…に)〈人〉‘を'入学させる;(競争などに)〈人・動物など〉‘を'参加させる《+『名』+『in』(『for』)+『名』》 / (…に)…‘を'記入する,登録する《+『名』+『in』(『into, on』)+『名』》 / 〈新しい生活・局面など〉‘に'入る / 〈異議など〉‘を'正式に申し出る / 『入る』 / 登場する
- 〈C〉(ペンキなどの)上塗り,塗装;(食物の)ころも,皮 / 〈U〉上旦用の布地
- ハナグマ(熱帯アメリカに住むアライグマ類の肉食動物)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/07/28 01:07:08」(JST)
[Wiki en表示]
|
This article has multiple issues. Please help improve it or discuss these issues on the talk page. |
|
This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. (December 2012) |
|
This article needs attention from an expert in Pharmacology. Please add a reason or a talk parameter to this template to explain the issue with the article. WikiProject Pharmacology (or its Portal) may be able to help recruit an expert. (February 2012) |
|
This article may need to be rewritten entirely to comply with Wikipedia's quality standards. You can help. The discussion page may contain suggestions. (February 2012) |
|
|
An enteric coating is a polymer barrier applied on oral medication. This helps by protecting drugs from the acidity of the stomach.[1]
Most enteric coatings work by presenting a surface that is stable at the highly acidic pH found in the stomach, but breaks down rapidly at a less acidic (relatively more basic) pH. For example, they will not dissolve in the gastric acids of the stomach (pH ~3), but they will in the alkaline (pH 7-9) environment present in the small intestine. Materials used for enteric coatings include fatty acids, waxes, shellac, plastics, and plant fibers.
Drugs that have an irritant effect on the stomach, such as aspirin, can be coated with a substance that will dissolve only in the small intestine. Likewise, certain groups of proton pump inhibitors (esomeprazole, omeprazole, pantoprazole and all grouped azoles) are acid-activated. For such types of drugs, enteric coating added to the formulation tends to avoid activation in the mouth and esophagus. However, it has been shown that this may lead to incomplete inhibition of platelets.[2]
Recently, some companies have begun to utilize enteric coatings on fish oil (omega-3 fatty acids) supplements. The coating prevents the fish oil capsules from being digested in the stomach, which has been known to cause a fishy reflux.
Sometimes the abbreviation "EC" is added beside the name of the drug to indicate that it has an enteric coating.
Composition of coatings
- Methyl acrylate-methacrylic acid copolymers
- Cellulose acetate succinate
- Hydroxy propyl methyl cellulose phthalate
- hydroxy propyl methyl cellulose acetate succinate (hypromellose acetate succinate)
- polyvinyl acetate phthalate (PVAP)
- methyl methacrylate-methacrylic acid copolymers
- Shellac
- Cellulose acetate trimellitate
- Sodium alginate
- Zein
See also
References
- ^ http://www.wellnessletter.com/ucberkeley/feature/should-your-aspirin-wear-a-coat/#
- ^ http://circ.ahajournals.org/content/early/2012/12/04/CIRCULATIONAHA.112.117283.abstract
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Novel starch based nano scale enteric coatings from soybean meal for colon-specific delivery.
- Sivapragasam N1, Thavarajah P2, Ohm JB3, Ohm JB3, Margaret K4, Thavarajah D5.
- Carbohydrate polymers.Carbohydr Polym.2014 Oct 13;111:273-9. doi: 10.1016/j.carbpol.2014.04.091. Epub 2014 May 2.
- Soybean meal was used to isolate resistant starch and produce nanoparticles, which could be potential coating materials for colonic nutrient and drug deliveries. The nanoparticles were in 40±33.2nm ranges. These nanoparticles were stable under simulated human physiological conditions. The degrees o
- PMID 25037352
- Design of lipotomes as a novel dual functioning nanocarrier for bioavailability enhancement of lacidipine: In-vitro and in-vivo characterization.
- ElKasabgy NA1, Elsayed I2, Elshafeey AH3.
- International journal of pharmaceutics.Int J Pharm.2014 Sep 10;472(1-2):369-79. doi: 10.1016/j.ijpharm.2014.06.048. Epub 2014 Jun 27.
- Lipotomes were designed to enhance lacidipine's oral bioavailability by improving its solubility and enhancing the oral lymphatic uptake. Lipotomes were prepared using cetyl alcohol and Tween(®) 80 using a thin film hydration technique. Cetyl alcohol was chosen for imparting a lipophilic environmen
- PMID 24979531
Japanese Journal
- Development of Enteric-Coated S/O Microcapsules Utilizing Edible Fats
- KANAYA Kento,SATO Masao
- Journal of chemical engineering of Japan 45(1), 82-88, 2012-03-01
- NAID 10030159084
- Development of Enteric-Coated S/O Microcapsules Utilizing Edible Fats
- Kanaya Kento,Sato Masao
- JOURNAL OF CHEMICAL ENGINEERING OF JAPAN 45(2), 82-88, 2012
- … Novel enteric-coated solid-in-oil (S/O) microcapsules were developed. …
- NAID 130000967343
Related Links
- An enteric coating is a polymer barrier applied on oral medication. This helps by protecting drugs from the pH (i.e. acidity) of the stomach. [1] Most enteric coatings work by presenting a surface that is stable at the highly acidic pH found in the stomach, but breaks down rapidly at a less acidic (relatively more ...
- enteric coating, a layer added to oral medications that allows the medication to pass through the stomach and be absorbed in the intestinal tract. The coating protects against the effects of stomach juices, which can interact with ...
Related Pictures
![Why Enteric Coating on Fish Oil Pills Fail](https://1mg.info/0/e/s/2179.jpg)
![Enteric-Coating of Fish Oil Softgels](https://1mg.info/0/e/s/2180.jpg)
![Hidup Lebih Bermanfaat Bersama Purtier](https://1mg.info/0/e/s/2181.jpg)
![What is enteric coating ?](https://1mg.info/0/e/s/2182.jpg)
![File:000719lg Enteric coated erythomycin](https://1mg.info/0/e/s/2183.jpg)
★リンクテーブル★
[★]
- 英
- enteric coat、enteric coating
- 関
- 腸溶性
[★]
- 関
- coat
[★]
[★]
- 同
- enteral