WordNet

very young; "at an early age"
before the usual time or the time expected; "she graduated early"; "the house was completed ahead of time" (同)ahead of time, too soon
in good time; "he awoke betimes that morning" (同)betimes
belonging to the distant past; "the early inhabitants of Europe"; "former generations"; "in other times" (同)former, other
at or near the beginning of a period of time or course of events or before the usual or expected time; "early morning"; "an early warning"; "early diagnosis"; "an early death"; "took early retirement"; "an early spring"; "early varieties of peas and tomatoes mature before most standard varieties"
being or occurring at an early stage of development; "in an early stage"; "early forms of life"; "early man"; "an early computer"
expected in the near future; "look for an early end to the negotiations"
of an early stage in the development of a language or literature; "the Early Hebrew alphabetical script is that used mainly from the 11th to the 6th centuries B.C."; "Early Modern English is represented in documents printed from 1476 to 1700"
fruiting spike of a cereal plant especially corn (同)spike, capitulum
attention to what is said; "he tried to get her ear"
good hearing; "he had a keen ear"; "a good ear for pitch"
the sense organ for hearing and equilibrium
the time period between dawn and noon; "I spent the morning running errands" (同)morn, morning time, forenoon
a British peer ranking below a marquess and above a viscount
an inability to sleep; chronic sleeplessness

PrepTutorEJDIC

(時間・時期が)『早い』,『初期の』 / 昔の / (普通より,予定より)早い / 近い将来の / (時間・時期的に)『早く』 / (予定・ふだんより)早く
〈C〉『耳』 / 《単数形で》『聴覚』,聴力,音感 / 《単数形で》じっと聞くこと,傾聴 / 〈C〉耳の形をした物
(麦・とうもろこしなどの)穂
〈C〉〈U〉『朝』,午前(午前0時または夜明けから正午まで) / 〈U〉《the~》(物事の)始まり,夜明け,黎明(れいめい)《+『of』+『名』》 / 《名詞の前にのみ用いて》朝の
(英国の)伯爵
不眠[症]

UpToDate Contents

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1. 不眠症の概要 overview of insomnia
2. 不眠症の臨床的特徴および診断 clinical features and diagnosis of insomnia
3. 緩和ケアにおける不眠症の概要 overview of insomnia in palliative care
4. 不眠症の治療 treatment of insomnia
5. パーキンソン病の臨床症状 clinical manifestations of parkinson disease

English Journal

Disturbed sleep as risk factor for the subsequent onset of bipolar disorder - Data from a 10-year prospective-longitudinal study among adolescents and young adults.

Ritter PS1, Höfler M2, Wittchen HU3, Lieb R4, Bauer M5, Pfennig A5, Beesdo-Baum K6.
Journal of psychiatric research.J Psychiatr Res.2015 Sep;68:76-82. doi: 10.1016/j.jpsychires.2015.06.005. Epub 2015 Jun 16.
There is ample data suggesting that individuals with bipolar disorder more frequently suffer from disturbed sleep even when euthymic. Since sleep is a process that is crucial for affective homeostasis, disturbed sleep in healthy individuals may be a risk factor for the subsequent onset of bipolar di
PMID 26228404

IL-1β and BDNF are associated with improvement in hypersomnia but not insomnia following exercise in major depressive disorder.

Rethorst CD1, Greer TL1, Toups MS1, Bernstein I2, Carmody TJ3, Trivedi MH1.
Translational psychiatry.Transl Psychiatry.2015 Aug 4;5:e611. doi: 10.1038/tp.2015.104.
Given the role of sleep in the development and treatment of major depressive disorder (MDD), it is becoming increasingly clear that elucidation of the biological mechanisms underlying sleep disturbances in MDD is crucial to improve treatment outcomes. Sleep disturbances are varied and can present as
PMID 26241349

Sleep Complaints and Metabolic Syndrome in an Elderly Population: The Three-City Study.

Akbaraly TN1, Jaussent I2, Besset A2, Bertrand M3, Barberger-Gateau P4, Ritchie K5, Ferrie JE6, Kivimaki M6, Dauvilliers Y7.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.Am J Geriatr Psychiatry.2015 Aug;23(8):818-28. doi: 10.1016/j.jagp.2014.10.001. Epub 2014 Oct 15.
OBJECTIVES: To assess whether sleep complaints (rather than clinically defined sleep disturbances) were associated with the metabolic syndrome (MetS) and each of its components in an elderly population.METHODS: Cross-sectional analyses of data from the French Three City Study, a large multicenter co
PMID 25499672