臓器移行性
WordNet
- holding office; "the in party"
- to or toward the inside of; "come in"; "smash in the door" (同)inwards, inward
- currently fashionable; "the in thing to do"; "large shoulder pads are in"
- directed or bound inward; "took the in bus"; "the in basket"
- wind instrument whose sound is produced by means of pipes arranged in sets supplied with air from a bellows and controlled from a large complex musical keyboard (同)pipe_organ
- a fully differentiated structural and functional unit in an animal that is specialized for some particular function
- a government agency or instrument devoted to the performance of some specific function; "The Census Bureau is an organ of the Commerce Department"
- a periodical that is published by a special interest group; "the organ of the communist party"
- your usual mood; "he has a happy disposition" (同)temperament
- a natural or acquired habit or characteristic tendency in a person or thing; "a swelling with a disposition to rupture"
- use recreational drugs (同)do drugs
- administer a drug to; "They drugged the kidnapped tourist" (同)dose
- a substance that is used as a medicine or narcotic
PrepTutorEJDIC
- 《具体的な場所,位置》 / …『の中に』(『で』) / …『において』,…で / 《intoの代りに移動を表す動詞と共に》…『の中へ』 / (乗り物)『に乗って』 / …『の状熊に』(『で』) / …『に従事して』,に属して / …『を身につけて』,に覆われて / 《『in』do『ing』の形で》…『するときに』,する際に(when) / 《時間》 / …『して』,…『が経過したあと』 / …『の間に』 / …『については』,…の点では / 《方法・手段・材料》…『で』 / 《人を目的語にして,性質・能力があることを示して》…の中に / …の目的で,のつもりで,として / 《比率割合》…のうちで,につき / 《過去分詞に伴って》…に[…されて] / 『中へ』(に) / 『在宅して』,帰って / (乗り物などが)『到着して』,(時期・季節が)来て / 出回って,流行して / 《俗》流行の,当世風の / 《話》特定の人々にのみ理解される
- 『オルガン』,パイプオルガン(pipe organ),リードオルガン(reed organ),電子オルガン(electronic organ),手回しオルガン(barrel organ) / (動植物の)『器官』 / (政党・会社などの)機関誌,機関紙 / 《しばしば複数形で》(行動・実施などの)組織,機関
- (人の)『気質』,性質 / 〈C〉(…する)傾向,(…したい)気持ち / 〈U〉『配置』,配列(arrangement) / 〈U〉(物事の最終的な)処理,処置;決着 / 〈U〉(物件などの)処分,譲渡,売却;使用権,自由裁量権
- 『薬』,薬品,薬剤 / 『麻薬』,麻酔剤 / 〈人〉‘に'薬(特に麻酔剤)を与える / 〈飲食物〉‘に'(麻酔薬・毒薬などの)薬を混ぜる
- indiumの化学記号
UpToDate Contents
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English Journal
- Multidrug Resistance-Associated Protein 4 (MRP4/ABCC4) Controls Efflux Transport of Hesperetin Sulfates in SULT1A3-Overexpressing HEK293 Cells.
- Sun H1, Wang X1, Zhou X1, Lu D1, Ma Z1, Wu B2.
- Drug metabolism and disposition: the biological fate of chemicals.Drug Metab Dispos.2015 Aug 3. pii: dmd.115.065953. [Epub ahead of print]
- Sulfonation is an important metabolic pathway for hesperetin. However, the mechanisms for cellular disposition of hesperetin and its sulfate metabolites are not fully established. In this study, disposition of hesperetin via the sulfonation pathway was investigated using HEK293 cells overexpressing
- PMID 26239185
- Metabolic disposition of the anti-cancer agent [(14)C]laromustine in male rats.
- Nassar AF1, Wisnewski A, King I.
- Xenobiotica; the fate of foreign compounds in biological systems.Xenobiotica.2015 Aug;45(8):711-21. doi: 10.3109/00498254.2015.1016475. Epub 2015 Mar 23.
- 1. Laromustine (VNP40101M, also known as Cloretazine) is a novel sulfonylhydrazine alkylating (anticancer) agent. This article describes the use of quantitative whole-body autoradiography (QWBA) and mass balance to study the tissue distribution, the excretion mass balance and pharmacokinetics afte
- PMID 25798740
- The Role of Extracellular Binding Proteins in the Cellular Uptake of Drugs: Impact on Quantitative In Vitro-to-In Vivo Extrapolations of Toxicity and Efficacy in Physiologically Based Pharmacokinetic-Pharmacodynamic Research.
- Poulin P1,2, Burczynski FJ3, Haddad S2.
- Journal of pharmaceutical sciences.J Pharm Sci.2015 Jul 14. doi: 10.1002/jps.24571. [Epub ahead of print]
- A critical component in the development of physiologically based pharmacokinetic-pharmacodynamic (PBPK/PD) models for estimating target organ dosimetry in pharmacology and toxicology studies is the understanding of the uptake kinetics and accumulation of drugs and chemicals at the cellular level. Th
- PMID 26173749
Japanese Journal
- Roles of drug transporters in the adverse reactions of drugs
- Impact of Genetic Variation in OATP Transporters to Drug Disposition and Response
- A Novel Method for Preparation of Animal Models of Liver Damage : Liver Targeting of Carbon Tetrachloride in Rats
Related Links
- 1. Pharmacol Rev. 2013 May 17;65(3):944-66. doi: 10.1124/pr.113.007518. Print 2013 Jul. Transporters and drug-drug interactions: important determinants of drug disposition and effects. König J, Müller F, Fromm MF. Uptake and efflux ...
- drug disposition, general term for the absorption, distribution, metabolism, and excretion of a drug that has been administered. disposition setting in place. disposition curve the graphic representation of changes in the blood ...
★リンクテーブル★
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- 英
- drug disposition in organs
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- abolish, abolition, arrange, arrangement, character, configuration, deploy, deployment, discard, disposal, dispose, nature, place, placement, propensity, property
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インジウム indium
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- 同
- drugs