WordNet
- work natural fibers into a thread; "spin silk"
- prolong or extend; "spin out a visit" (同)spin out
- the act of rotating rapidly; "he gave the crank a spin"; "it broke off after much twisting" (同)twirl, twist, twisting, whirl
- a distinctive interpretation (especially as used by politicians to sway public opinion); "the campaign put a favorable spin on the story"
- a short drive in a car; "he took the new car for a spin"
- a swift whirling motion (usually of a missile)
- revolve quickly and repeatedly around ones own axis; "The dervishes whirl around and around without getting dizzy" (同)spin around, whirl, reel, gyrate
- form a web by making a thread; "spiders spin a fine web"
- make up a story; "spin a yarn"
- stream in jets, of liquids; "The creek spun its course through the woods"
- twist and turn so as to give an intended interpretation; "The Presidents spokesmen had to spin the story to make it less embarrassing"
- a decrease in size of an organ caused by disease or disuse (同)wasting, wasting away
- undergo atrophy; "Muscles that are not used will atrophy"
- any weakening or degeneration (especially through lack of use) (同)withering
- situated farthest from point of attachment or origin, as of a limb or bone
- directed away from the midline or mesial plane of the body
- of or relating to or consisting of muscle; "muscular contraction"
- having or suggesting great physical power or force; "the muscular and passionate Fifth Symphony"
- of or relating to the spine or spinal cord; "spinal cord"; "spinal injury"
PrepTutorEJDIC
- (羊毛などから)〈糸など〉‘を'『紡ぐ』《+『名』+『out of』+『名』〈羊毛〉》,(糸などに)〈羊毛など〉‘を'紡ぐ《+『名』〈羊毛〉+『into』+『名』》 / 〈クモ・カイコなどが〉〈糸〉‘を'『吐く』;〈巣・繭〉‘を'かける / …‘を'くるくる回す / 〈物語など〉‘を'作る,話す / 『糸を紡ぐ』;〈クモ・カイコなどが〉糸を吐く / 〈こまなどが〉くるくる回る / 〈車などが〉疾走する / 〈頭などが〉くらくらする / 〈C〉〈U〉くるくる回すこと;回転 / 〈C〉《単数形で》(車などの)一走り / 〈C〉(飛行機の)きりもみ降下 / 〈C〉《単数形で》(価値などの)急落
- (栄養不良などによる)萎縮(いしゅく) / (一般的に)衰退,退化 / 萎縮する,衰退する / …'を'萎縮させる,衰退させる
- 中心から遠い,末梢(まっしょう)[部]の,末端[部]の
- 『助肉の』,筋肉でできた / 筋肉による / 筋肉の発達した
- 背骨の / せき髄麻酔
UpToDate Contents
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- 1. 脊髄性筋萎縮症 spinal muscular atrophy
- 2. 新生児における筋緊張低下を引き起こす末梢神経および筋肉の障害に関する概要 overview of peripheral nerve and muscle disorders causing hypotonia in the newborn
- 3. Etiology and evaluation of the child with weakness
- 4. シャルコーマリートゥース病などの一次性の遺伝性運動感覚性ニューロパチー hereditary primary motor sensory neuropathies including charcot marie tooth disease
- 5. 肢帯型筋ジストロフィー limb girdle muscular dystrophy
English Journal
- Cross-disease comparison of amyotrophic lateral sclerosis and spinal muscular atrophy reveals conservation of selective vulnerability but differential neuromuscular junction pathology.
- Comley LH1, Nijssen J1, Frost-Nylen J1, Hedlund E1.
- The Journal of comparative neurology.J Comp Neurol.2016 May 1;524(7):1424-42. doi: 10.1002/cne.23917. Epub 2015 Nov 23.
- Neuromuscular junctions are primary pathological targets in the lethal motor neuron diseases spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS). Synaptic pathology and denervation of target muscle fibers has been reported prior to the appearance of clinical symptoms in mouse model
- PMID 26502195
- Monoubiquitination of survival motor neuron regulates its cellular localization and Cajal body integrity.
- Han KJ1, Foster D1, Harhaj EW2, Dzieciatkowska M1, Hansen K1, Liu CW3.
- Human molecular genetics.Hum Mol Genet.2016 Apr 1;25(7):1392-405. doi: 10.1093/hmg/ddw021. Epub 2016 Jan 28.
- Low levels of the survival motor neuron (SMN) protein cause spinal muscular atrophy, the leading genetic disorder for infant mortality. SMN is ubiquitously expressed in various cell types and localizes in both the cytoplasm and the nucleus, where it concentrates in two subnuclear structures termed C
- PMID 26908624
- CNS uptake of bortezomib is enhanced by P-glycoprotein inhibition: implications for spinal muscular atrophy.
- Foran E1, Kwon DY2, Nofziger JH3, Arnold ES3, Hall MD4, Fischbeck KH3, Burnett BG5.
- Neurobiology of disease.Neurobiol Dis.2016 Apr;88:118-24. doi: 10.1016/j.nbd.2016.01.008. Epub 2016 Jan 11.
- The development of therapeutics for neurological disorders is constrained by limited access to the central nervous system (CNS). ATP-binding cassette (ABC) transporters, particularly P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP), are expressed on the luminal surface of capillarie
- PMID 26792401
Japanese Journal
- A novel mutation in glycyl-tRNA synthetase caused Charcot-Marie-Tooth disease type 2D with facial and respiratory muscle involvement
- , , , , , ,
- 臨床神経学 54(11), 911-915, 2014
- … symptoms include distal wasting and weakness, usually with some sensory impairment. … Distal weakness appeared in childhood and became worse with age. … Comprehensive analysis of known CMT-related genes revealed a novel heterozygous c.815T>A, p.L218Q mutation in glycyl-tRNA synthetase (GARS), a causative gene for both CMT type 2D (CMT2D) and distal spinal muscular atrophy type V (dSMA-V). …
- NAID 130004706051
- 神経疾患の克服―新しい時代への挑戦―
- 水澤 英洋
- 臨床神経学 53(11), 893-897, 2013
- … Recent progress in researches on etiologies and pathogeneses of many neurological diseases, however, has made it become possible to treat some diseases such as bulbo-spinal muscular atrophy and Alzheimer's disease not only symptomatically but also in the sense of disease modification. …
- NAID 130004505463
- 脊髄性筋萎縮症I型児(者)におけるスイッチ使用状況・言語発達・上肢機能・QOL : 親に対するアンケート調査より
- 境 信哉,真木 誠,境 直子,須藤 章,加藤 光広,齋藤 伸治
- 脳と発達 44(6), 465-471, 2012-11-01
- … 【目的】脊髄性筋萎縮症 (spinal muscular atrophy; …
- NAID 10031122022
Related Links
- Distal spinal muscular atrophy type 1 (DSMA1), also known as spinal muscular atrophy with respiratory distress type 1 (SMARD1) and hereditary motor neuropathy type 6 (HMN6) — is a rare neuromuscular disorder involving death of motor ...
- Distal Spinal Muscular Atrophy. J Muthukrishnan*, R Varadarajulu**, SR Mehta** *, AP Singh+. Abstract. Spinal muscular atrophies (SMA) are clinically heterogenous group of motor system disorders characterised by progressive pure lower ...
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★リンクテーブル★
| リンク元 | 「遠位型脊髄性筋萎縮症」「progressive muscular atrophy」「遠位型脊髄性筋萎縮」 |
| 関連記事 | 「distal」「spinal」「muscular」「spin」「atrophy」 |
「遠位型脊髄性筋萎縮症」
「progressive muscular atrophy」
「遠位型脊髄性筋萎縮」
「distal」
- adj.
- 遠位の、遠心性の、末端の、遠位性の
「spinal」
- adj.
- 脊髄の、脊髄性の、脊柱の
「muscular」
- adj.
- 筋肉の、筋の
「spin」
「atrophy」
- n.