びまん性管内性増殖性糸球体腎炎
WordNet
- spread out; not concentrated in one place; "a large diffuse organization"
- move outward; "The soldiers fanned out" (同)spread, spread out, fan out
- lacking conciseness; "a diffuse historical novel"
- nephritis marked by inflammation of the glomeruli of the kidney; characterized by decreased production of urine and by the presence of blood and protein in the urine and by edema
- (of light rays) subjected to scattering by reflection from a rough surface or transmission through a translucent material; "diffused light"
- spreading by diffusion (同)diffusive, dispersive, disseminative
PrepTutorEJDIC
- 〈光・熱・液体など〉‘を'散らす,放散する,拡散させる / 〈学問・知識など〉‘を'広める,普及させる / 散る,放散する,拡散する / 広まる,普及する / 広く散った,広がった / 〈文体などが〉締まりのない,散漫な
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English Journal
- Recurrent proliferative glomerulonephritis with monoclonal IgG deposits of IgG2λ subtype in a transplanted kidney: a case report.
- Sumida K1, Ubara Y, Marui Y, Nakamura M, Takaichi K, Tomikawa S, Fujii T, Ohashi K.Author information 1Nephrology Center, Toranomon Hospital, Tokyo, Japan. k-sumida@toranomon.gr.jp.AbstractProliferative glomerulonephritis with monoclonal immunoglobulin G (IgG) deposits (PGNMID) is a recently described disease entity. In the kidney transplantation literature, only 6 recurrent and 2 de novo PGNMID cases, including 7 of the IgG3 subclass (6 with κ light chain and 1 with λ light chain) and 1 of the IgG1 subclass (λ light chain), have been described to date. We describe a 52-year-old man with end-stage renal disease whose primary glomerular disease had been suggested to be membranoproliferative glomerulonephritis. The patient underwent living related donor kidney transplantation and presented with proteinuria, hematuria, and decreased kidney function at 4 months posttransplantation. Biopsy of the transplanted kidney showed diffuse endocapillary proliferative glomerulonephritis. Immunofluorescence microscopy showed prominent granular glomerular staining for IgG, C3, and λ light chain, with IgM, IgA, and κ light chain undetectable. Immunofluorescence staining for IgG subclass showed signal for IgG2 only. Retrospective analysis of the native kidney biopsy specimen also showed the same monoclonal glomerular staining for the IgG2λ subtype. These findings led us to the diagnosis of PGNMID of the IgG2λ subtype as both the primary glomerular disease and recurrent disease in the transplanted kidney. Recurrence was treated with high-dose prednisolone, which decreased proteinuria, hematuria, and serum creatinine level. The case demonstrates that PGNMID of the IgG2λ subtype also can recur in the transplanted kidney.
- American journal of kidney diseases : the official journal of the National Kidney Foundation.Am J Kidney Dis.2013 Sep;62(3):587-90. doi: 10.1053/j.ajkd.2013.01.013. Epub 2013 Mar 6.
- Proliferative glomerulonephritis with monoclonal immunoglobulin G (IgG) deposits (PGNMID) is a recently described disease entity. In the kidney transplantation literature, only 6 recurrent and 2 de novo PGNMID cases, including 7 of the IgG3 subclass (6 with κ light chain and 1 with λ light chain)
- PMID 23474011
- Acute post-streptococcal glomerulonephritis with acute kidney injury in nephrotic syndrome with the glomerular deposition of nephritis-associated plasmin receptor antigen.
- Kokuzawa A1, Morishita Y, Yoshizawa H, Iwazu K, Komada T, Akimoto T, Saito O, Oda T, Takemoto F, Ando Y, Muto S, Yumura W, Kusano E.Author information 1Division of Rheumatology and Clinical Immunology, Jichi Medical University, Japan.AbstractWe herein report the case of a 17-year-old man who developed an increased plasma creatinine level (11.1 mg/dL) and oliguria with massive proteinuria (27.3 g/day) four weeks after an abraded wound to his right knee. The histology of the renal biopsy specimens showed diffuse endocapillary proliferative glomerulonephritis with the deposition of nephritis-associated plasmin receptor in the glomerulus. A case of acute kidney injury due to nephrotic syndrome caused by acute post-streptococcal glomerulonephritis was diagnosed. His renal function and proteinuria were improved with supportive care, including hemodialysis, without the administration of immunosuppressive agents.
- Internal medicine (Tokyo, Japan).Intern Med.2013;52(18):2087-91.
- We herein report the case of a 17-year-old man who developed an increased plasma creatinine level (11.1 mg/dL) and oliguria with massive proteinuria (27.3 g/day) four weeks after an abraded wound to his right knee. The histology of the renal biopsy specimens showed diffuse endocapillary proliferativ
- PMID 24042518
- Proliferative glomerulonephritis with monoclonal immunoglobulin G3κ deposits in association with parvovirus B19 infection.
- Fujita E1, Shimizu A, Kaneko T, Masuda Y, Ishihara C, Mii A, Higo S, Kajimoto Y, Kanzaki G, Nagasaka S, Iino Y, Katayama Y, Fukuda Y.Author information 1Department of Internal Medicine (Division of Neurology, Nephrology, and Rheumatology), Nippon Medical School, Tokyo 113-8602, Japan.AbstractProliferative glomerulonephritis with monoclonal immunoglobulin G deposits is a recently described disease entity, characterized by nonorganized electron-dense deposits in glomeruli and immunofluorescence findings indicating monoclonal immunoglobulin G deposits. The pathogenesis of many cases of proliferative glomerulonephritis with monoclonal immunoglobulin G deposits remains unknown. We herein report 2 patients with parvovirus B19 infection who developed acute nephritic syndrome with hypocomplementemia (patient 1) or persistent proteinuria and congestive heart failure (patient 2); however, neither patient had detectable levels of serum monoclonal immunoglobulin G. Renal biopsy in both patients showed diffuse endocapillary proliferative glomerulonephritis with monoclonal immunoglobulin G3κ deposits, and electron microscopy showed nonorganized electron-dense deposits mainly in the subendothelial and mesangial areas. Clinical symptoms, abnormal laboratory findings, and urinary abnormalities recovered spontaneously in both cases within 4 weeks. Our 2 cases may be the first reported patients with proliferative glomerulonephritis with monoclonal immunoglobulin G deposits possibly associated with parvovirus B19 infection. Virus infection-associated immune disorders could be implicated in the pathogenesis of proliferative glomerulonephritis with monoclonal immunoglobulin G deposits.
- Human pathology.Hum Pathol.2012 Dec;43(12):2326-33. doi: 10.1016/j.humpath.2012.04.004. Epub 2012 Jul 21.
- Proliferative glomerulonephritis with monoclonal immunoglobulin G deposits is a recently described disease entity, characterized by nonorganized electron-dense deposits in glomeruli and immunofluorescence findings indicating monoclonal immunoglobulin G deposits. The pathogenesis of many cases of pro
- PMID 22819999
Japanese Journal
- Acute Post-streptococcal Glomerulonephritis with Acute Kidney Injury in Nephrotic Syndrome with the Glomerular Deposition of Nephritis-associated Plasmin Receptor Antigen
- Acute Glomerulonephritis in an Immunocompetent Elderly Woman after Contact with a Child who Had Been Diagnosed as Erythema Infectiosum
- Patient with diffuse mesangial and endocapillary proliferative glomerulonephritis with hypocomplementemia and elecvted anti-streptolysin O treated with prednisolone, angiotensin-converting enzyme inhibitor, and angiotensin II receptor antagonist
★リンクテーブル★
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- 英
- endocapillary proliferative glomerulonephritis
- 関
- びまん性管内性増殖性糸球体腎炎 diffuse endocapillary proliferative glomerulonephritis
- 急性糸球体腎炎
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- 英
- diffuse endocapillary proliferative glomerulonephritis
- 関
- 管内性増殖性糸球体腎炎 endocapillary proliferative glomerulonephritis
[★]
- 関
- diffusely、diffusion、diffusional、diffusive、disseminated、pervasive、spread、widespread
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- 関
- multiplicative、productive、productively、proliferating
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糸球体腎炎 GN