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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/04/21 00:04:04」(JST)

Dibekacin is an aminoglycoside antibiotic.

It has been used in combination with sulbenicillin.^[1]

References

^ Aonuma S, Ariji F, Oizumi K, Konno K (June 1987). "Electron microscopy of Pseudomonas aeruginosa treated with sulbenicillin and dibekacin" (^{[DEAD LINK]}). Tohoku J. Exp. Med. 152 (2): 119–28. doi:10.1620/tjem.152.119. PMID 3114912.

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Synthesis and antibacterial activity of 1-N-[(S)-ω-amino-2-hydroxyalkyl] derivatives of dibekacin, 5-deoxydibekacin, 3'-deoxykanamycin A and gentamicin B.

Umemura E1, Sakamoto Y1, Takahashi Y1, Miyake T1.
The Journal of antibiotics.J Antibiot (Tokyo).2015 Feb 25. doi: 10.1038/ja.2015.6. [Epub ahead of print]
PMID 25712399

Identification of a novel 6'-N-aminoglycoside acetyltransferase, AAC(6')-Iak, from a multidrug-resistant clinical isolate of Stenotrophomonas maltophilia.

Tada T1, Miyoshi-Akiyama T1, Dahal RK2, Mishra SK2, Shimada K1, Ohara H3, Kirikae T4, Pokhrel BM2.
Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2014 Oct;58(10):6324-7. doi: 10.1128/AAC.03354-14. Epub 2014 Aug 4.
Stenotrophomonas maltophilia IOMTU250 has a novel 6'-N-aminoglycoside acetyltransferase-encoding gene, aac(6')-Iak. The encoded protein, AAC(6')-Iak, consists of 153 amino acids and has 86.3% identity to AAC(6')-Iz. Escherichia coli transformed with a plasmid containing aac(6')-Iak exhibited decreas
PMID 25092711

Hamada Y, Suematsu H, Hirai J, Yamagishi Y, Mikamo H.
The Japanese journal of antibiotics.Jpn J Antibiot.2014 Aug;67(4):233-9.
Arbekacin (ABK) is one of aminoglycosides which has indications for septicemia and pneumonia caused by methicillin-resistant Staphylococcus aureus (MRSA) in Japan. ABK shows good clinical and microbiological efficacies also against Gram-negative bacteria (GNB), including Pseudomonas aeruginosa. In a
PMID 25420319

In vitro Assessment of the Cytotoxicity of Six Topical Antibiotics to Four Cultured Ocular Surface Cell Lines

増田陽平,多田弘史,宮本雅友,本村悟朗,吉村洋一
整形外科と災害外科 57(4), 595-598, 2008
手指の骨感染症に対し抗生剤含有セメントを適応した2症例につき検討を行ったので報告する．症例1，61歳男性，透析患者で2005年7月中指壊死に対し環指基節骨切断した，術後5日切断部より排膿を認めた（Serratia感染），そのため再切断とパニマイシン（DKB）含有セメント留置を行った．8週後セメント除去を行った．症例2，57歳女性，糖尿病患者で2006年9月中指に木片が刺さり末節骨MRSA骨髄炎とな …
NAID 130004460736

西圭史,金井隆康,永井茂,篠原高雄,小林治,河合伸
日本化学療法学会雑誌 56(6), 625-630, 2008
… これを検証する目的で, 杏林大学医学部付属病院において2006年1月1日から12月31日までの期間にamikacin (AMK), dibekacin (DKB), gentamicin (GM), isepamicin (ISP), tobramycin (TOB) が投与された362症例について, OD群とMDD群について臨床効果と副作用についての比較検討を行った。 …
NAID 130004298377

リンク元	「ジベカシン」「DKB」
拡張検索	「dibekacin sulfate」

Dibekacin
Systematic (IUPAC) name
	(2S,3R,4S,5S,6R)-4-Amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(aminomethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Registry Number	34493-98-6
ATC code	J01GB09
PubChem	CID 470999
ChemSpider	413666
UNII	45ZFO9E525
KEGG	D07811
ChEMBL	CHEMBL560976
Chemical data
Formula	C18H37N5O8
Molecular mass	451.52 g/mol
	InChI InChI=1S/C18H37N5O8/c19-4-6-1-2-7(20)17(28-6)30-15-8(21)3-9(22)16(14(15)27)31-18-13(26)11(23)12(25)10(5-24)29-18/h6-18,24-27H,1-5,19-23H2/t6-,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1; Key:JJCQSGDBDPYCEO-XVZSLQNASA-N ;