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English Journal
- Chemoreflex and baroreflex alterations in Parkinsonism induced by 6-OHDA in unanesthetized rats.
- Ariza D1, Lopes FN1, Crestani CC2, Martins-Pinge MC3.
- Neuroscience letters.Neurosci Lett.2015 Oct 21;607:77-82. doi: 10.1016/j.neulet.2015.09.024. Epub 2015 Sep 25.
- Parkinson's disease (PD) is mainly characterized by motor signals. However, non-motor signals also affect and decrease the quality of life of PD patients. Among these non-motor signs are cardiovascular disorders as orthostatic hypotension, postprandial hypotension and cardiac arrhythmias, which may
- PMID 26409036
- Perinatal 6-Hydroxydopamine to Produce a Lifelong Model of Severe Parkinson's Disease.
- Kostrzewa JP1, Kostrzewa RA2, Kostrzewa RM3, Brus R4, Nowak P5.
- Current topics in behavioral neurosciences.Curr Top Behav Neurosci.2015 Oct 17. [Epub ahead of print]
- The classic rodent model of Parkinson's disease (PD) is produced by unilateral lesioning of pars compacta substantia nigra (SNpc) in adult rats, producing unilateral motor deficits which can be assessed by dopamine (DA) D2 receptor (D2-R) agonist induction of measurable unilateral rotations. Bilater
- PMID 26475156
- Lifelong Rodent Model of Tardive Dyskinesia-Persistence After Antipsychotic Drug Withdrawal.
- Kostrzewa RM1, Brus R2.
- Current topics in behavioral neurosciences.Curr Top Behav Neurosci.2015 Oct 16. [Epub ahead of print]
- Tardive dyskinesia (TD), first appearing in humans after introduction of the phenothiazine class of antipsychotics in the 1950s, is now recognized as an abnormality resulting predominately by long-term block of dopamine (DA) D2 receptors (R). TD is thus reproduced in primates and rodents by chronic
- PMID 26472552
Japanese Journal
- パーキンソン病およびその関連疾患における運動時血圧調節異常
- 出口 一志
- 臨床神経学 53(11), 1379-1381, 2013
- 自律神経不全を主症状とする多系統萎縮症や純粋型自律神経不全症は運動時低血圧(EIH),運動後の血圧低下遷延と起立性低血圧増強を示す.また運動中に過剰な血圧上昇を示すこともある.一方,パーキンソン病(PD)では運動時および運動後の血圧が健常者よりも有意に低く,一部の例はEIHの症状を示す.ピーク運動時の心拍数増加が不十分なPDでは運動時の血圧上昇も不良である.しかし心臓交感神経脱支配の有無は運動時血 …
- NAID 130004505454
- パーキンソン病(PD)の循環系予備能と運動処方の実際
- 平山 正昭,中村 友彦,祖父江 元
- 臨床神経学 53(11), 1376-1378, 2013
- PDは,錐体外路疾患としてだけでなく数々の非運動症状をともなう広範な病変を持った疾患である.とくに,心循環器系に関しては,早期からMIBGの異常がみられることが知られている.起立性低血圧などもパーキンソン病の早期の症状としてみられる.さらに,心臓のβ1刺激薬による脱過敏をみとめ,運動時に心拍出量の増加に乏しく循環予備能の低下を招いている.このため疲労感との関連が高く,心交感神経が異常であるほど疲労 …
- NAID 130004505453
- 出口 一志
- 自律神経 = The Autonomic nervous system 49(3), 166-168, 2012-09-15
- NAID 10031047355
Related Links
- Author links open the overlay panel. Numbers correspond to the affiliation list which can be exposed by using the show more link. ... For a wide variety of neuro-muscular preparations denervation has been shown to result in a rapid ...
- The Definition of Denervation Supersensitivity. The nervous system is a highly adaptive organ. Even within a single lifetime, the ability to respond to changes in the environment is paramount to an organism's fitness. Adaptations occur ...
Related Pictures
★リンクテーブル★
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- 関
- denervation supersensitivity
[★]
- 関
- hypersensitivity、hypersusceptibility、irritable、irritation、supersensitive
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- 関
- (vt.)denarvate