WordNet
- the 9th letter of the Roman alphabet (同)i
PrepTutorEJDIC
- 『私は』私が
- iodineの化学記号
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- 1. β-ラクタマーゼ阻害剤、カルバペネム系、およびモノバクタム系抗菌薬の併用 combination beta lactamase inhibitors carbapenems and monobactams
English Journal
- [Meropenem--therapeutic recommendation after twenty years of presence on pharmaceutical market].
- Paczkowska M, Garbacki P, Zalewski P, Talaczyńska A, Cielecka-Piontek J.
- Postȩpy higieny i medycyny doświadczalnej (Online).Postepy Hig Med Dosw (Online).2014 May 8;68(0):441-5. doi: 10.5604/17322693.1101541.
- Meropenem is the first representative of carbapenem analogues with methyl group, which has been applied in medicine. This drug has been approved by FDA (Food and Drug Administration) in 1996. Available results of clinical trials and scientific reports point surprising synergism of combination of mer
- PMID 24864096
- Even apparently insignificant chemical deviations among bioequivalent generic antibiotics can lead to therapeutic nonequivalence: the case of meropenem.
- Agudelo M1, Rodriguez CA, Pelaez CA, Vesga O.
- Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2014;58(2):1005-18. doi: 10.1128/AAC.00350-13. Epub 2013 Nov 25.
- Several studies with animal models have demonstrated that bioequivalence of generic products of antibiotics like vancomycin, as currently defined, do not guarantee therapeutic equivalence. However, the amounts and characteristics of impurities and degradation products in these formulations do not vi
- PMID 24277034
- Enzymatic production of Cilastatin intermediate via highly enantioselective hydrolysis of methyl (±)-2,2-dimethylcyclopropane carboxylate using newly isolated Rhodococcus sp. ECU1013.
- Liu CH1, Pan J, Ye Q, Xu JH.
- Applied microbiology and biotechnology.Appl Microbiol Biotechnol.2013 Sep;97(17):7659-67. doi: 10.1007/s00253-013-5038-z. Epub 2013 Jun 27.
- (S)-(+)-2,2-Dimethylcyclopropane carboxylic acid [(S)-(+)-DMCPA] is a key chiral intermediate for production of Cilastatin, an excellent renal dehydropeptidase-I inhibitor. In this study, a new method for preparation of (S)-(+)-DMCPA with microbial esterases was investigated. A microbial screening p
- PMID 23807665
Japanese Journal
- CW-270033, a Novel Pyrrolidinyl-thio Carbapenem, Has Potent Antimicrobial Activity in Vitro and in Vivo(Miscellaneous)
- , , [他], , , , ,
- Biological & pharmaceutical bulletin 30(3), 575-579, 2007-03-01
- … CW-270033 was also found to be resistant to hydrol sis b the mouse renal deh dro e tidase I DHP-1 enzyme. …
- NAID 110006239206
- Doripenem のヒト dehydropeptidase-I に対する安定性
- 山野 佳則,川井 悠唯,湯通堂 隆
- 日本化学療法学会雜誌 = Japanese journal of chemotherapy 53, 92-95, 2005-07-20
- … 新規注射用カルバペネム系抗菌薬doripenemのヒト腎dehydropeptidase-I (DHP-I) に対する安定性を検討した。 …
- NAID 10016601108
- Synthesis and Structure-activity Relationships of 1.BETA.-Methylcarbapenems with Quaternary Ammonium Side Chains.
- , , , , ,
- The Journal of Antibiotics 51(8), 757-770, 1998
- … These 1β-methylcarbapenems, one type having a (2S, 4S)-2-[1, 1-dimethyl-2-(1-piperazinyl)carbonyl]pyrrolidinio-4-ylthio group and the other type having a (2S, 4S)-2-(4-carbamoylmethyl-4-methylhomopiperazinio-1-ylcarbonyl)pyrrolidin-4-ylthio group, show potent and well balanced antibacterial activity as well as high stability against dehydropeptidase-I. …
- NAID 130003503492
Related Links
- dehydropeptidase-I / DPEP1 summary,dehydropeptidase-I / DPEP1 protein information: function for dehydropeptidase-I / DPEP1 protein, involvement in disease, sequence length, domain, post-translational modification, subunit ...
- Stability of doripenem against human renal dehydropeptidase-I Yoshinori Yamano, Yui Kawai and Takashi Yutsudo Discovery Research Laboratories, Shionogi & Co., Ltd., 3―1―1 Futaba-cho, Toyonaka, Osaka, Japan We evaluated ...
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★リンクテーブル★
| リンク元 | 「デヒドロペプチダーゼI」 |
| 関連記事 | 「I」「Id」「dehydropeptidase I」 |
「デヒドロペプチダーゼI」
- カルバペネム系抗菌薬を分解する酵素。特に腎臓にある。
「I」