デカルボキシラーゼ、脱炭酸酵素
- 関
- carboxy-lyase
WordNet
- any of the enzymes that hydrolize the carboxyl group
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/12/04 13:50:19」(JST)
[Wiki en表示]
Carboxy-lyases, also known as decarboxylases, are carbon–carbon lyases that add or remove a carboxyl group from organic compounds. These enzymes catalyze the decarboxylation of amino acids, beta-keto acids and alpha-keto acids.[1]
Contents
- 1 Classification and nomenclature
- 2 Examples
- 3 See also
- 4 References
- 5 External links
Classification and nomenclature
Carboxy-lyases are categorized under EC number 4.1.1.[2] Usually, they are named after the substrate whose decarboxylation they catalyze, for example Pyruvate decarboxylase catalyzes the decarboxylation of Pyruvate
Examples
- Aromatic-L-amino-acid decarboxylase
- Glutamate decarboxylase
- Histidine decarboxylase
- Ornithine decarboxylase
- Phosphoenolpyruvate carboxylase
- Pyruvate decarboxylase
- RuBisCO – the only carboxylase that leads to a net fixation of carbon dioxide
- Uridine monophosphate synthetase
- Uroporphyrinogen III decarboxylase
See also
- Enzymes
- Lyases
- List of EC numbers of enzymes belonging to category EC 4.1
References
- ^ http://www.expasy.org/cgi-bin/get-entries?KW=Decarboxylase
- ^ http://www.biochem.ucl.ac.uk/bsm/enzymes/ec4/ec01/ec01/index.html
External links
- Carboxy-Lyases at the US National Library of Medicine Medical Subject Headings (MeSH)
Proteins: enzymes
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Activity |
- Active site
- Binding site
- Catalytic triad
- Oxyanion hole
- Enzyme promiscuity
- Catalytically perfect enzyme
- Coenzyme
- Cofactor
- Enzyme catalysis
- Enzyme kinetics
- Lineweaver–Burk plot
- Michaelis–Menten kinetics
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Regulation |
- Allosteric regulation
- Cooperativity
- Enzyme inhibitor
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Classification |
- EC number
- Enzyme superfamily
- Enzyme family
- List of enzymes
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Types |
- EC1 Oxidoreductases(list)
- EC2 Transferases(list)
- EC3 Hydrolases(list)
- EC4 Lyases(list)
- EC5 Isomerases(list)
- EC6 Ligases(list)
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- Biochemistry overview
- Enzymes overview
- By EC number: 1.1
- 2
- 3
- 4
- 5
- 6
- 7
- 8
- 10
- 11
- 13
- 14
- 15-18
- 2.1
- 3.1
- 4.1
- 5.1
- 6.1-3
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Carbon-carbon lyases (EC 4.1)
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4.1.1: Carboxy-lyases |
- Acetoacetate decarboxylase
- Adenosylmethionine decarboxylase
- Aromatic L-amino acid decarboxylase
- Glutamate decarboxylase
- Histidine decarboxylase
- Lysine decarboxylase
- Malonyl-CoA decarboxylase
- Ornithine decarboxylase
- Oxaloacetate decarboxylase
- Phosphoenolpyruvate carboxykinase
- Phosphoenolpyruvate carboxylase
- Phosphoribosylaminoimidazole carboxylase
- Pyrophosphomevalonate decarboxylase
- Pyruvate decarboxylase
- RuBisCO
- Uridine monophosphate synthetase/Orotidine 5'-phosphate decarboxylase
- Uroporphyrinogen III decarboxylase
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4.1.2: Aldehyde-lyases |
- Fructose-bisphosphate aldolase
- Aldolase A
- Aldolase B
- Aldolase C
- 2-hydroxyphytanoyl-CoA lyase
- Threonine aldolase
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4.1.3: Oxo-acid-lyases |
- Isocitrate lyase
- 3-hydroxy-3-methylglutaryl-CoA lyase
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4.1.99: Other |
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- Biochemistry overview
- Enzymes overview
- By EC number: 1.1
- 2
- 3
- 4
- 5
- 6
- 7
- 8
- 10
- 11
- 13
- 14
- 15-18
- 2.1
- 3.1
- 4.1
- 5.1
- 6.1-3
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UpToDate Contents
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English Journal
- Imidazoline binding sites mediates anticompulsive-like effect of agmatine in marble-burying behavior in mice.
- Dixit MP1, Thakre PP1, Pannase AS1, Aglawe MM1, Taksande BG1, Kotagale NR2.
- European journal of pharmacology.Eur J Pharmacol.2014 Jun 5;732:26-31. doi: 10.1016/j.ejphar.2014.02.045. Epub 2014 Mar 19.
- Agmatine is a cationic amine formed by decarboxylation of l-arginine by the mitochondrial enzyme arginine decarboxylase and widely distributed in mammalian brain. Although the precise function of endogenous agmatine has been largely remained unclear, its exogenous administration demonstrated benefic
- PMID 24657463
- Intravenous immunoglobulin and rituximab for cerebellar ataxia with glutamic Acid decarboxylase autoantibodies.
- Planche V1, Marques A, Ulla M, Ruivard M, Durif F.
- Cerebellum (London, England).Cerebellum.2014 Jun;13(3):318-22. doi: 10.1007/s12311-013-0534-3.
- Cerebellar ataxia associated with glutamic acid decarboxylase autoantibodies (GAD-ab) is a rare and usually slow progressive disease with moderate to severe gait and limb ataxia, dysarthria, and nystagmus. The treatment for this condition is still being discussed. We report the cases of three patien
- PMID 24218114
- Antithyroid antibodies as a potential marker of autoimmune-mediated late onset temporal lobe epilepsy.
- Miró J1, Fortuny R2, Juncadella M3, Aiguabella M4, Veciana M4, Castañer S5, Santurino M4, Falip M6.
- Clinical neurology and neurosurgery.Clin Neurol Neurosurg.2014 Jun;121:46-50. doi: 10.1016/j.clineuro.2014.03.017. Epub 2014 Mar 25.
- In one third of patients with epilepsy starting in adulthood the aetiology remains undetermined. Some patients with late onset temporal lobe epilepsy (TLE) together with memory decline have elevated antithyroid antibodies.PURPOSE: To compare the prevalence of antithyroid antibodies (aTR-ab) in adult
- PMID 24793474
Japanese Journal
- Improved conversion of cinnamaldehyde derivatives to diol compounds via a pyruvate decarboxylase-dependent mechanism in budding yeast
- Journal of bioscience and bioengineering 121(3), 265-267, 2016-03
- NAID 40020772919
- 活性型ビタミンB₆と安価な食材ヒエを用いた簡便な測定技術の開発
Related Links
- Decarboxylase definition, any of the class of enzymes that catalyze the release of carbon dioxide from the carboxyl group of certain organic acids. See more. Thesaurus Translate Puzzles & Games Reference Word of the Day Blog ...
- decarboxylase /de·car·box·y·lase/ (de″kahr-bok´sĭ-lās) any enzyme of the lyase class that catalyzes the removal of a carbon dioxide molecule from carboxylic acids. de·car·box·yl·ase (dē′kär-bŏk′sə-lās′, -lāz′) n. Any of various ...
Related Pictures
★リンクテーブル★
[★]
- 英
- carboxylase
- 同
- カルボキシ基転移酵素
- 脱炭酸酵素 デカルボキシラーゼ decarboxylase、
- 基質(有機化合物(糖、アミノ酸)にCO2を付与したり除去したりする酵素
- カルボキシラーゼとデカルボキシラーゼの区別はどの反応に着目したかによる?
デカルボキシラーゼ
- カルボン酸のカルボキシ基(-COOH)を炭酸として遊離させる。
[★]
カルボキシリアーゼ、(通称)脱炭酸酵素
- 関
- decarboxylase
[★]
- 英
- decarboxylase
- 関
- カルボキシラーゼ、脱炭酸酵素
[★]
- 英
- decarboxylase
- 関
- 脱炭酸酵素
[★]
(リポ酸を含有するグリシン脱炭酸酵素複合体の構成タンパク質)グリシン脱炭酸酵素複合体Hタンパク質
[★]
ピルビン酸脱炭酸酵素、ピルビン酸デカルボキシラーゼ
[★]
チロシン脱炭酸酵素、チロシンデカルボキシラーゼ
[★]
ピルビン酸デカルボキシラーゼ
[★]
グルタミン酸脱炭酸酵素 GAD