deamino arginine vasopressin

デアミノアルギニンバソプレシン

WordNet

1. hormone secreted by the posterior pituitary gland (trade name Pitressin) and also by nerve endings in the hypothalamus; affects blood pressure by stimulating capillary muscles and reduces urine flow by affecting reabsorption of water by kidney tubules (同)antidiuretic_hormone, ADH, Pitressin
2. a bitter tasting amino acid found in proteins and necessary for nutrition; its absence from the diet leads to a reduced production of spermatozoa

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. バソプレシンおよびデスモプレシン刺激試験 vasopressin and desmopressin stimulation test
• 2. 常染色体優性多発性嚢胞腎の経過および治療 course and treatment of autosomal dominant polycystic kidney disease
• 3. 昇圧剤および強心剤の使用 use of vasopressors and inotropes
• 4. 腎性尿崩症の臨床症状および原因 clinical manifestations and causes of nephrogenic diabetes insipidus
• 5. 成人における低ナトリウム血症の治療の概要 overview of the treatment of hyponatremia in adults

English Journal

• Reversal of Thienopyridine-Induced Platelet Dysfunction Following Desmopressin Administration.

• Levine M, Swenson S, McCormick T, Henderson SO, Thomas SH, Markland FS.SourceDepartment of Emergency Medicine, Section of Medical Toxicology, University of Southern California, 1200 North State Street, Room 1011, Los Angeles, CA, 90033, USA, Michael.Levine@bannerhealth.com.
• Journal of medical toxicology : official journal of the American College of Medical Toxicology.J Med Toxicol.2012 Nov 18. [Epub ahead of print]
• Adenosine diphosphate (ADP)-receptor antagonists are widely used for thrombus prevention, although reversing their platelet dysfunction is difficult. This study evaluated the ability of desmopressin to reverse clopidogrel-induced platelet dysfunction. Sprague-Dawley rats received either clopidogrel
• PMID 23161280

• Defective renal water handling in transgenic mice over-expressing human CD39/NTPDase1.

• Zhang Y, Morris KL, Sparrow SK, Dwyer KM, Enjyoji K, Robson SC, Kishore BK.SourceNephrology Research, Department of Veterans Administration Salt Lake City Health Care System, Salt Lake City, UT 84148, USA.
• American journal of physiology. Renal physiology.Am J Physiol Renal Physiol.2012 Aug 1;303(3):F420-30. Epub 2012 May 23.
• Ectonucleoside triphosphate diphosphohydrolase-1 hydrolyzes extracellular ATP and ADP to AMP. Previously, we showed that CD39 is expressed at several sites within the kidney and thus may impact the availability of type 2 purinergic receptor (P2-R) ligands. Because P2-Rs appear to regulate urinary co
• PMID 22622462

Japanese Journal

• A Case of a Novel Mutant Vasopressin Receptor-Dependent Nephrogenic Diabetes Insipidus with Bilateral Non-Obstructive Hydronephrosis in a Middle Aged Man : Differentiation from Aquaporin-Dependent Nephrogenic Diabetes Insipidus by the Response of factor VIII and von Willebrand Factor to 1-Deamino-8-D-Arginine Vasopressin Administration

• MIYAKOSHI MASASHI,KAMOI KYUZI,UCHIDA SHINICHI,SASAKI SEI
• Endocrine journal 50(6), 809-814, 2003-12-01
• … We describe a case of a novel mutant vasopressin 2 receptor (V2R)-dependent nephrogenic diabetes insipidus (NDI) with bilateral non-obstructive hydronephrosis in a middle aged man. … This could be distinguished from aquaporin 2 (AQP2)-dependent NDI by the response of factor VIII and von Willebrand factor (vWF) to 1-deamino-8-D-arginine vasopressin (DDAVP) administration. …
• NAID 10011825753

• Oral DDAVP is a Good Alternative Therapy for Patients with Central Diabetes Insipidus: Experience of Five-Year Treatment

• FUKUDA Izumi,HIZUKA Naomi,TAKANO Kazue
• Endocrine Journal 50(4), 437-443, 2003
• … We studied the efficacy and safety of oral 1-deamino-8-D-arginine-vasopressin (DDAVP) tablets in 9 patients, aged 17-36 years, with central diabetes insipidus (DI). …
• NAID 130004443061

• Prevention of Demyelination Induced by Rapid correction of Hyponatremia in Mice

• SUGIMURA Yoshihisa,TAKAGI Hiroshi,MURASE Takashi,HOSHINO Shin,HAYASAKA Shizu,OISO Yutaka,MURATA Yoshiharu
• Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University 46(1/2), 58-61, 2002-12
• 国立情報学研究所で電子化したコンテンツを使用している。
• NAID 110000029084

---

★リンクテーブル★

リンク元

「デスモプレシン」

「デスモプレシン」

　　[★]

英

desmopressin

同

1-desamino-8-D-arginine vasopressin, DDAVP, 1-deamino-8-D-arginine vasopressin、デアミノアルギニンバソプレッシン デアミノアルギニンバソプレシン deamino arginine vasopressin

化

酢酸デスモプレシン desmopressin acetate

商

Stimate、デスモプレシン点鼻薬、デスモプレシン注、ミニリンメルト

関

バソプレシン。脳下垂体ホルモン剤

• アルギニンバソプレシン誘導体;尿崩症治療薬
• 副作用の発現がバソプレシンより少ないが、水中毒にはやはり注意する必要がある。(QB.D-257)

I. NATURALLY OCCURRING VASOPRESSIN-LIKE PEPTIDES?
??A. Vertebrates?	A?	W?	X?	Y?	Z?
????1. Mammals
??????? Arginine? vasopressin* (AVP) (human beings and other mammals)	NH2	Tyr	Phe	Gln	Arg
???????Lypressin* (pigs, marsupials)	NH2	Tyr	Phe	Gln	Lys
???????Phenypressin (macropodids)	NH2	Phe	Phe	Gln	Arg
????2. Nonmammalian vertebrates
Vasotocin	NH2	Tyr	Ile	Gln	Arg
??B. Invertebrates?
????1. Arginine conopressin (Conus striatus)?	NH2	Ile	Ile	Arg	Arg
????2. Lysine conopressin (Conus geographicus)?	NH2	Phe	Ile	Arg	Lys
????3. Locust subesophageal ganglia peptide	NH2	Leu	Ile	Thr	Arg
II. SYNTHETIC VASOPRESSIN PEPTIDES?
??A. V1-selective agonists?
????1. V1a-Selective Agonist [Phe2, Ile3, Orn8]AVP	NH2	Phe	Ile	Gln	Orn
????2. V1b-Selective Agonist Deamino [D-3-(3'-pyridyl)-Ala2]AVP	H	D-3-(3'-pyridyl)-Ala2	Phe	Gln	Arg
??B. V2-selective agonists?
????1. Desmopressin* (DDAVP)	H	Tyr	Phe	Gln	D-Arg?
????2. Deamino[Val4, D-Arg8]AVP	H	Tyr	Phe	Val	D-Arg?
III. NONPEPTIDE AGONIST?
A. OPC-51803?