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English Journal
- The first trial of CIM331, a humanized anti-human IL-31 receptor A antibody, for healthy volunteers and patients with atopic dermatitis to evaluate safety, tolerability and pharmacokinetics of a single dose in a randomised, double-blind, placebo-controlled study.
- Nemoto O1, Furue M2, Nakagawa H3, Shiramoto M4, Hanada R5, Matsuki S6, Imayama S6, Kato M1, Hasebe I1, Taira K6,7, Yamamoto M8, Mihara R8, Kabashima K9, Ruzicka T10, Hanifin J11, Kumagai Y12.
- The British journal of dermatology.Br J Dermatol.2015 Sep 26. doi: 10.1111/bjd.14207. [Epub ahead of print]
- BACKGROUND: Interleukin-31 (IL-31) is considered as a responsible cytokine for the development of pruritus in humans. At present, no available evidence has been reported on the safety and efficacy of blocking the IL-31 signal in humans for the amelioration of pruritus in atopic dermatitis (AD). CIM3
- PMID 26409172
- Detection of glucocorticoid receptor agonists in effluents from sewage treatment plants in Japan.
- Suzuki G1, Sato K2, Isobe T3, Takigami H4, Brouwer A5, Nakayama K2.
- The Science of the total environment.Sci Total Environ.2015 Sep 15;527-528:328-34. doi: 10.1016/j.scitotenv.2015.05.008. Epub 2015 May 14.
- Glucocorticoids (GCs) are widely used as anti-inflammatory drugs. Our previous study demonstrated that several GCs such as cortisol and dexamethasone (Dex) were frequently detected in effluents collected from Japanese sewage treatment plants (STPs) in 2012. In this study, we used the GC-Responsive C
- PMID 25965047
Japanese Journal
- Safety evaluation of a new topical corticoid, alclometasone dipropionate (S-3460).
- 須貝 哲郎
- 皮膚 28(3), 251-260, 1986
- … 0.1 % Hydrocortisone 17-butyrate (HB) ointment was chosen as a control. … Serum cortisol was estimated one day before the experiment started, two days after the vehicle was applied, 1, 3 and 5 days after the drug was applied, and 2nd and 6th day after the application finished. … A significant decrease of serum cortisol level in the HB group was found at a level of 0.05, compared with the level before the experiment, while no significant difference in the S-3460 group. …
- NAID 130004044977
- 外用コルチコステロイド剤 0.1% Hydrocortisone 17-Butyrate Creamの密封包帯療法:―とくに吉草酸ベタメタゾンとの全身的影響と臨床効果の比較―
- Hydrocortisone 17-Butyrate 研究班
- 西日本皮膚科 38(6), 956-970, 1976
- … 皮膚疾患の外用治療において優れた臨床効果を有し, かつ比較的全身影響が少ないといわれている副腎皮質ホルモン剤0.1% hydrocortisone 17-butyrate cream(以下0.1% HBC)の外用時の全身的影響(主に下垂体?副腎皮質系を中心として), 臨床効果, ならびに副作用について0.12% betamethasone 17-valerate cream(以下0.12% BV-C)を対照とし二重盲検法に準じ比較検討した。 …
- NAID 130004830478
Related Links
- Chromatograph the Standard solution and the Test solution, and record the peak responses as directed for Procedure: the resolution, R, between hydrocortisone butyrate and any impurity is not less than 1.0; and the column ...
- Chromatograph the Standard solution and the Test solution,and record the peak responses as directed for Procedure: the resolution, R, between hydrocortisone butyrate and any impurity is not less than 1.0;and the column efficiency ...
★リンクテーブル★
[★]
酪酸、酪酸エステル、酪酸塩
- 関
- butanoic acid、butyric acid
[★]
コルチゾール
- 同
- コルチゾール