Cペプチド
WordNet
- amide combining the amino group of one amino acid with the carboxyl group of another; usually obtained by partial hydrolysis of protein
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English Journal
- Insulin resistance is increased in alopecia areata patients.
- Karadag AS, Ertugrul DT, Bilgili SG, Takci Z, Tutal E, Yilmaz H.SourceFaculty of Medicine, Department of Dermatology, Yuzuncu Yil University, Van, Turkey. drayserem@yahoo.com
- Cutaneous and ocular toxicology.Cutan Ocul Toxicol.2013 Jun;32(2):102-6. doi: 10.3109/15569527.2012.713418. Epub 2012 Aug 24.
- Increased insulin resistance (IR) has been found in androgenetic alopecia in several studies. However, IR has not been investigated in alopecia areata (AA). We aimed to investigate IR in AA patients and the controls. Anthropometric and demographic data were obtained from 51 AA patients and 36 contro
- PMID 22916967
- Interaction of divalent cations with peptide fragments from Parkinson's disease genes.
- Remelli M, Peana M, Medici S, Delogu LG, Zoroddu MA.SourceDepartment of Chemical and Pharmaceutical Sciences, University of Ferrara, Ferrara, Italy. rmm@unife.it.
- Dalton transactions (Cambridge, England : 2003).Dalton Trans.2013 May 7;42(17):5964-74. doi: 10.1039/c2dt32222f. Epub 2012 Nov 30.
- Protected Ac-PDEKHEL-NH2 (PK9-H) and Ac-FCGDGANDCG-NH2 (PK9-C) peptide fragments corresponding to sequences from residues 1165 to 1171 and 1184 to 1193, respectively, in the Park9 encoded protein from Parkinson's disease gene were tested for their protonation and complex formation capabilities with
- PMID 23202360
- Adipose tissue-derived mesenchymal stromal cells efficiently differentiate into insulin-producing cells in pancreatic islet microenvironment both in vitro and in vivo.
- Karaoz E, Okcu A, Unal ZS, Subasi C, Saglam O, Duruksu G.SourceKocaeli University, Center for Stem Cell and Gene Therapies Research and Practice, Kocaeli, Turkey. Electronic address: ekaraoz@hotmail.com.
- Cytotherapy.Cytotherapy.2013 May;15(5):557-70. doi: 10.1016/j.jcyt.2013.01.005. Epub 2013 Feb 4.
- BACKGROUND AIMS: Differentiation or reprogramming of stem cells could be achieved by remodulating the microenvironment, which regulates the fate of cells by soluble factors and contacts. By providing an in vivo-like microenvironment, directional and functional differentiation of stem cells could be
- PMID 23388582
Japanese Journal
- 抗GAD抗体陰性かつ抗IA-2抗体陽性を呈した高齢発症1型糖尿病の1例
- 千葉 優子,鄭 仁熙,金原 嘉之,田村 嘉章,森 聖二郎,井藤 英喜,荒木 厚
- 日本老年医学会雑誌 50(3), 404-408, 2013
- 症例は83歳，女性．78歳時の健診では空腹時血糖値90 mg/dl，HbA1c 5.7％（NGSP値）であった．80歳時より口渇・多飲・多尿・体重減少を認め，HbA1c 12.2％と高値を指摘され糖尿病と診断された．入院にて加療され，グリメピリド，メトホルミン内服にて血糖コントロールは良好となった．しかし81歳時には随時血糖433 mg/dl，HbA1c 9.2％と再度急激な悪化を認めた．当時抗G …
- NAID 130004485881
- Urea-based Oligomers as Peptide Mimics : Connecting Structure and Function
- マイクロ抗体 : 進化分子工学による分子標的ペプチドの創出
- 藤井 郁雄
- 有機合成化学協会誌 68(5), 543-550, 2010-05-01
- … The molecule is a helix–loop–helix peptide, which is stable against natural enzymes <I>in vivo</I> … The peptide is composed of three structural regions, N–terminal α–helix, C–terminal α–helix, and flexible connecting loop. … Since the peptide folds by virtue of the interactions between the amino acid residues positioned inside the helix–loop–helix, the solvent–exposed, outside residues were randomized to give a library of MicroAntibodies. …
- NAID 10026869196
Related Links
- Ming Liu, Jose Ramos-Castañeda ‡ and Peter Arvan From the Diabetes Research and Training Center and the Department of Developmental and Molecular Biology, Albert Einstein ...
- The Fiber Disease... and N-acetyl muramic acid. The NAM residues are cross-linked with oligopeptides. The terminal peptide is D-alanine although other amino acids are ... 20mm long. Inlet and outlet ports are laser ablated. The ...
★リンクテーブル★
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- 英
- C-peptide、connecting peptide
- 同
- C-ペプチド
- 関
- インスリン
http://www.crc-group.co.jp/crc/q_and_a/127.html
糖尿病患者ではインスリン分泌能の指標となり、24時間尿中CPRが20μg/日以下、または空腹時血中CPRが0.5ng/mL以下であれば、インスリン分泌が高度に低下した状態（インスリン依存状態）と考えられ、インスリン治療が必要とされます。
さらに、2型糖尿病患者において治療法を選択する上で、早朝空腹時のCPRインデックス（CPI）が有用な指標として使用されています。
CPI＝血中CPR÷血糖値×100
CPIが1.2以上の場合、食事・経口薬治療で、0.8未満の場合、インスリン治療で良好な血糖コントロールが得られると報告されています。
ただし、CPRの大部分は腎において代謝・排泄されるため、腎機能障害では血中CPRが高値に、尿中CPRが低値に傾くので注意を要します。また、24時間尿中CPR排泄量では正確な蓄尿と、日差間のバラツキがあるため連続3日間の測定が重要です。
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コネクチン
- 関
- titin