WordNet

present at birth but not necessarily hereditary; acquired during fetal development (同)inborn, innate
relating to or involving or causing hemolysis; "hemolytic anemia" (同)haemolytic
a deficiency of red blood cells (同)anaemia
a lack of vitality (同)anaemia
genus of terrestrial or lithophytic ferns having pinnatifid fronds; chiefly of tropical America (同)genus Anemia

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/04/19 09:44:05」(JST)

Congenital hemolytic anemia (or hereditary hemolytic anemia) refers to hemolytic anemia which is primarily due to congenital disorders.^[1]

Basically classified by causative mechanism, types of congenital hemolytic anemia include:

Genetic conditions of RBC Membrane
- Hereditary spherocytosis
- Hereditary elliptocytosis
Genetic conditions of RBC metabolism (enzyme defects). This group is sometimes called congenital nonspherocytic (hemolytic) anemia, which is a term for a congenital hemolytic anemia without spherocytosis, and usually excluding hemoglobin abdormalities as well, but rather encompassing defects of glycolysis in the erythrocyte.^[2]
- Glucose-6-phosphate dehydrogenase deficiency (G6PD or favism)
- Pyruvate kinase deficiency
- Aldolase A deficiency
Hemoglobinopathies^[3]/genetic conditions of hemoglobin
- Sickle cell anemia
- Congenital dyserythropoietic anemia
- Thalassemia

^ Rahman SA, Jamal CY (June 2002). "Congenital hemolytic anemia in Bangladesh: types and clinical manifestations". Indian Pediatr 39 (6): 574–7. PMID 12084953.
^ medconditions.net > Hemolytic Congenital, Nonspherocytic Anemia Definition Retrieved April 15, 2011
^ Shah A (November 2004). "Hemoglobinopathies and other congenital hemolytic anemia". Indian J Med Sci 58 (11): 490–3. PMID 15567909.

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1. 小児における溶血性貧血の概要 overview of hemolytic anemias in children
2. 脾腫を有する小児に対するアプローチ approach to the child with an enlarged spleen
3. ピルビン酸キナーゼ欠損症 pyruvate kinase deficiency
4. 不安定ヘモグロビン変異体 unstable hemoglobin variants
5. 輸血関連の免疫性および非免疫性溶血 transfusion associated immune and non immune mediated hemolysis

Gallagher PG1, Glader B2,3.
Pediatric blood & cancer.Pediatr Blood Cancer.2016 May;63(5):771-2. doi: 10.1002/pbc.25922. Epub 2016 Feb 2.
PMID 26836632

Two Novel Missense Mutations and a 5bp Deletion in the Erythroid-Specific Promoter of the PKLR Gene in Two Unrelated Patients With Pyruvate Kinase Deficient Transfusion-Dependent Chronic Nonspherocytic Hemolytic Anemia.

Kager L1,2, Minkov M1,3, Zeitlhofer P4, Fahrner B1, Ratzinger F5, Boztug K1,6, Dossenbach-Glaninger A7, Haas OA1,2,4.
Pediatric blood & cancer.Pediatr Blood Cancer.2016 May;63(5):914-6. doi: 10.1002/pbc.25878. Epub 2016 Jan 5.
We report two children with severe chronic hemolytic anemia, the cause of which was difficult to establish because of transfusion dependency. Reduced erythrocyte pyruvate kinase activity in their asymptomatic parents provided the diagnostic clues for mutation screening of the PKLR gene and revealed
PMID 26728349
PMID 27031109

A Case of Congenital Nonspherocytic Hemolytic Anemia Associated with Glucosephosphate Isomerase (GPI) Deficiency-GPI ′Kinki′

Three Cases in Two Families with Congenital Nonspherocytic Hemolytic Anemia due to Defective Glucosephosphate Isomerase--GPI Matsumoto

Congenital nonspherocytic hemolytic anemia due to glucose-6-phosphate dehydrogenase deficiency in a japanese child Clinical and metabolic studies

リンク元	「先天性非球状性溶血性貧血」「先天性非球状赤血球性溶血性貧血」
関連記事	「congenita」「hemolytic」「congenital」