WordNet

unconscious from a blow or shock or intoxication; "the boxer was out cold"; "pass out cold"
a mild viral infection involving the nose and respiratory passages (but not the lungs); "will they never find a cure for the common cold?" (同)common_cold
the sensation produced by low temperatures; "he shivered from the cold"; "the cold helped clear his head" (同)coldness
without compunction or human feeling; "in cold blood"; "cold-blooded killing"; "insensate destruction" (同)cold-blooded, inhuman, insensate
sexually unresponsive; "was cold to his advances"; "a frigid woman" (同)frigid
lacking originality or spontaneity; no longer new; "moth-eaten theories about race"; "stale news" (同)stale, dusty, moth-eaten
(color) giving no sensation of warmth; "a cold bluish grey"
extended meanings; especially of psychological coldness; without human warmth or emotion; "a cold unfriendly nod"; "a cold and unaffectionate person"; "a cold impersonal manner"; "cold logic"; "the concert left me cold"
feeling or showing no enthusiasm; "a cold audience"; "a cold response to the new play"
having a low or inadequate temperature or feeling a sensation of coldness or having been made cold by e.g. ice or refrigeration; "a cold climate"; "a cold room"; "dinner has gotten cold"; "cold fingers"; "if you are cold, turn up the heat"; "a cold beer"
having lost freshness through passage of time; "a cold trail"; "dogs attempting to catch a cold scent"
lacking the warmth of life; "cold in his grave"
marked by errorless familiarity; "had her lines cold before rehearsals started"
of a seeker; far from the object sought
so intense as to be almost uncontrollable; "cold fury gripped him"
responsive to physical stimuli; "a mimosas leaves are sensitive to touch"; "a sensitive voltmeter"; "sensitive skin"; "sensitive to light"
hurting; "the tender spot on his jaw" (同)sore, raw, tender
being susceptible to the attitudes, feelings, or circumstances of others; "sensitive to the local community and its needs"
of or pertaining to classified information or matters affecting national security
(genetics) any event that changes genetic structure; any alteration in the inherited nucleic acid sequence of the genotype of an organism (同)genetic mutation, chromosomal_mutation
a change or alteration in form or qualities
a pass between mountain peaks (同)gap

PrepTutorEJDIC

『寒い』,冷たい;冷えた,冷やした / (性格・態度などが)『冷たい』,冷淡な,熱意のない;無情な,冷酷な / (物事が)人をがっかりさせる,つまらない / (色調が)冷たい,寒色の / (獲物のにおい臭が)かすかな,弱い / 《話》(打撃などで)意識を失った,失神した / 完全に,全く / 〈U〉《しばしばthe~》『寒さ』,寒け,冷たさ / 〈C〉,時に〈U〉『かぜ』,感冒
(五感が)『敏感な』,感じやすい / 物事を非常に気にする,神経過敏な / 感光性の;(器械などが)感度のよい
変化,俸転 / (生物の)突然変異;その変種
(山脈の)鞍部(あんぶ),山あい

UpToDate Contents

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1. アレルギー性鼻炎：臨床症状、疫学、および診断 allergic rhinitis clinical manifestations epidemiology and diagnosis
2. チクングンヤ熱 chikungunya fever
3. コロナウイルス coronaviruses
4. 成人における急性気管支炎 acute bronchitis in adults
5. 副鼻腔炎と喘息の関係 relationships between rhinosinusitis and asthma

English Journal

A single amino acid substitution in the nonstructural protein 2CATPase of poliovirus causes conditional defects in encapsidation and uncoating.

Asare E1, Mugavero J1, Jiang P1, Wimmer E2, Paul AV1.
Journal of virology.J Virol.2016 Apr 13. pii: JVI.02877-15. [Epub ahead of print]
The specificity of encapsidation of C-cluster enteroviruses depends on an interaction between capsid proteins and nonstructural protein 2CATPase In particular, residue N252of poliovirus 2CATPaseinteracts with VP3 of coxsackie virus A20, in the context of a chimeric virus. Poliovirus 2CATPasehas impo
PMID 27076638

The Escherichia coli Cryptic Prophage Protein YfdR Binds to DnaA and Initiation of Chromosomal Replication Is Inhibited by Overexpression of the Gene Cluster yfdQ-yfdR-yfdS-yfdT.

Noguchi Y1, Katayama T1.
Frontiers in microbiology.Front Microbiol.2016 Mar 3;7:239. doi: 10.3389/fmicb.2016.00239. eCollection 2016.
The initiation of bacterial chromosomal replication is regulated by multiple pathways. To explore novel regulators, we isolated multicopy suppressors for the cold-sensitive hda-185 ΔsfiA(sulA) mutant. Hda is crucial for the negative regulation of the initiator DnaA and the hda-185 mutation causes s
PMID 26973617

Spring loading a pre-cleavage intermediate for hairpin telomere formation.

Lucyshyn D1, Huang SH1, Kobryn K2.
Nucleic acids research.Nucleic Acids Res.2015 Jul 13;43(12):6062-74. doi: 10.1093/nar/gkv497. Epub 2015 May 24.
The Borrelia telomere resolvase, ResT, forms the unusual hairpin telomeres of the linear Borrelia replicons in a process referred to as telomere resolution. Telomere resolution is a DNA cleavage and rejoining reaction that proceeds from a replicated telomere intermediate in a reaction with mechanist
PMID 26007659