WordNet
- a gastrointestinal hormone that stimulates the secretion of pancreatic enzymes and the contraction and emptying of the gall bladder; its release is stimulated by the presence of fatty acids and amino acids in the small intestine
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- 1. コレシストキニンの生理学 physiology of cholecystokinin
- 2. 膵外分泌機能検査 pancreatic exocrine function tests
- 3. 成人における胆嚢機能障害 functional gallbladder disorder in adults
- 4. ガストリンの生理学 physiology of gastrin
- 5. 胃酸分泌の生理学 physiology of gastric acid secretion
English Journal
- Two cholecystokinin receptor subtypes are identified in goldfish, being the CCKAR involved in the regulation of intestinal motility.
- Tinoco AB1, Valenciano AI1, Gómez-Boronat M1, Blanco AM1, Nisembaum LG1, De Pedro N1, Delgado MJ2.
- Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.Comp Biochem Physiol A Mol Integr Physiol.2015 Sep;187:193-201. doi: 10.1016/j.cbpa.2015.05.027. Epub 2015 Jun 5.
- Cholecystokinin (CCK) plays a key role in the digestive physiology of vertebrates. However, very little is known about the role of CCK on intestinal functions in fish. The present study identifies two CCK receptor subtypes in a stomachless teleost, the goldfish (Carassius auratus), and investigates
- PMID 26051613
- Acute heat stress up-regulates neuropeptide Y precursor mRNA expression and alters brain and plasma concentrations of free amino acids in chicks.
- Ito K1, Bahry MA1, Hui Y1, Furuse M1, Chowdhury VS2.
- Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.Comp Biochem Physiol A Mol Integr Physiol.2015 Sep;187:13-9. doi: 10.1016/j.cbpa.2015.04.010. Epub 2015 Apr 29.
- Heat stress causes an increase in body temperature and reduced food intake in chickens. Several neuropeptides and amino acids play a vital role in the regulation of food intake. However, the responses of neuropeptides and amino acids to heat-stress-induced food-intake regulation are poorly understoo
- PMID 25933935
- Preparation and application of a novel molecularly imprinted solid-phase microextraction monolith for selective enrichment of cholecystokinin neuropeptides in human cerebrospinal fluid.
- Ji X1, Li D1, Li H1.
- Biomedical chromatography : BMC.Biomed Chromatogr.2015 Aug;29(8):1280-9. doi: 10.1002/bmc.3418. Epub 2015 Jan 23.
- A novel molecularly imprinted polymer (MIP) monolith for highly selective extraction of cholecystokinin (CCK) neuropeptides was prepared in a micropipette tip. The MIPs were synthesized by epitope imprinting technique and the polymerization conditions were investigated and optimized. The synthesized
- PMID 25616243
Japanese Journal
- コレシストキニン・パンクレオザイミン(CCK-PZ) (広範囲 血液・尿化学検査 免疫学的検査(第7版・4)その数値をどう読むか) -- (内分泌学的検査 膵・消化管関係)
- 日本臨床 68(-), 544-546, 2010-07
- NAID 40017200805
- Inhibition of cholecystokinin-pancreozymin release by somatostatin
- Lancet ii, 166-168, 1997
- NAID 10014884317
- Octreotide Decreases Biliary and Pancreatic Exocrine Function, and Induces Steatorrhea in Healthy Subjects.
- Internal Medicine 33(10), 593-596, 1994
- NAID 130000770966
Related Links
- cholecystokinin [ko″le-sis″to-ki´nin] a polypeptide hormone secreted in the small intestine, which stimulates gallbladder contraction and secretion of pancreatic enzymes. cho·le·cys·to·ki·nin (CCK), (kō'lē-sis-tō-kī'nin), [MIM*118440] A ...
- コレシストキニンパンクレオザイミン【cholecystokinin-pancreozymin】とは。意味や解説、類語。十二指腸の粘膜の細胞から分泌されるホルモン。消化酵素に富む膵液 (すいえき) の分泌を促し、また胆嚢 (たんのう) を収縮させるので、胆汁 ...
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★リンクテーブル★
| リンク元 | 「コレシストキニン」 |
| 関連記事 | 「pancreozymin」「cholecystokinin」 |
「コレシストキニン」
- 英
- cholecystokinin, CCK
- 同
- コレシストキニン・パンクレオザイミン cholecystokinin pancreozymin CCK-PZ
- パンクレオザイミン pancreozymin
- 関
- 消化管ホルモン、胆嚢収縮物質
まとめ
- 小腸内タンパク質分解産物、酸、脂肪酸、アルコールが刺激となって、小腸のI細胞から分泌され、消化酵素に富む膵液を分泌させる。またオッディ括約筋を弛緩させ、胆嚢を収縮させて胆汁の分泌を促す。
分泌部位と細胞
作用
胃
- ↓：胃排出(First Aid step 1 p.269)
- ↑：胃酸分泌(CBT QB vol2 p.295)
胆嚢
- ↑：胆嚢を収縮 (SP.706)
- ↑：胆嚢外分泌腺増加
胆膵管
膵
- ↑：膵液分泌(First Aid step 1 p.269)
- ↑：外分泌腺増加
調節 (First Aid step 1 p.269)
↑
- 脂肪酸、アミノ酸
↓
- セクレチン
- 胃のpH<1.5
臨床関連
- 胆石症
- 脂肪摂取→CCK↑→胆汁↑→いたいっ