WordNet
- depress or discourage; "The news of the citys surrender chilled the soldiers"
- a sensation of cold that often marks the start of an infection and the development of a fever (同)shivering
- coldness due to a cold environment (同)iciness, gelidity
- a sudden numbing dread (同)pall
- provoking fear terror; "a scary movie"; "the most terrible and shuddery...tales of murder and revenge" (同)scarey, scary, shivery, shuddery
PrepTutorEJDIC
- 『寒気』,冷気・冷たさ / 『寒さ』,悪寒 / 興ざめ,いや気,失意 / ‥'を'『冷やす』 / ‥'を'『ぞっとさせる』,‘に'寒けを覚えさせる / 〈興味・意気込み〉'を'くじく,そぐ / 令える,寒けを覚える / 『冷たい』,こんやりする;寒けのする / 『冷淡な』,よそよそしい
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/08/17 16:46:51」(JST)
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This article is about the physiological symptom. For other uses, see Chill (disambiguation).
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This article does not cite any references or sources. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. (July 2014) |
Chills is a feeling of coldness occurring during a high fever, but sometimes is also a common symptom which occurs alone in specific people. It occurs during fever due to the release of cytokines and prostaglandins as part of the inflammatory response, which increases the set point for body temperature in the hypothalamus. The increased set point causes the body temperature to rise (pyrexia), but also makes the patient feel cold or chills until the new set point is reached. Shivering also occurs along with chills because the patient's body produces heat during muscle contraction in a physiological attempt to increase body temperature to the new set point. When it does not accompany a high fever it is normally a light chill. Sometimes a chill of medium power and short duration may occur during a scare, especially in scares of fear, commonly interpreted like or confused by trembling.
Causes
Chills are commonly caused by inflammatory diseases, and may be caused by scares, especially by the fear scares or jumpscares. Sometimes they happen in specific people almost all the time, in a slight power, or it less commonly happens in an generically healthy person.
See also
- Cold chill
- Fever
- Goose bumps
- Night sweats
- Shivering
Symptoms and signs: general / constitutional (R50–R61, 780.6–780.9)
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Temperature |
heat: |
- Fever
- Fever of unknown origin
- Drug-induced fever
- Postoperative fever
- Hyperhidrosis
- e.g., Sleep hyperhidrosis; "sweating"
- Hyperpyrexia
- Hyperthermia
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cold: |
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Aches/Pains |
- Headache
- Chronic pain
- Cancer pain
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Malaise and fatigue |
- Atrophy
- Debility (or asthenia)
- Lassitude
- Lethargy
- Muscle tremors
- Tenderness
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Miscellaneous |
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UpToDate Contents
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English Journal
- Mifamurtide in metastatic and recurrent osteosarcoma: A patient access study with pharmacokinetic, pharmacodynamic, and safety assessments.
- Anderson PM, Meyers P, Kleinerman E, Venkatakrishnan K, Hughes DP, Herzog C, Huh W, Sutphin R, Vyas YM, Shen V, Warwick A, Yeager N, Oliva C, Wang B, Liu Y, Chou A.Author information University of Texas M.D. Anderson Cancer Center, Houston, Texas.AbstractPURPOSE: This non-randomized, patient-access protocol, assessed both safety and efficacy outcomes following liposomal muramyl-tripeptide-phosphatidylethanolamine (L-MTP-PE; mifamurtide) in patients with high-risk, recurrent and/or metastatic osteosarcoma.
- Pediatric blood & cancer.Pediatr Blood Cancer.2014 Feb;61(2):238-44. doi: 10.1002/pbc.24686. Epub 2013 Aug 31.
- PURPOSE: This non-randomized, patient-access protocol, assessed both safety and efficacy outcomes following liposomal muramyl-tripeptide-phosphatidylethanolamine (L-MTP-PE; mifamurtide) in patients with high-risk, recurrent and/or metastatic osteosarcoma.METHODS: Patients received mifamurtide 2 mg
- PMID 23997016
- Report of a Phase I Evaluation of Dose and Schedule of Interleukin-1 Alpha and Cyclophosphamide in Patients with Advanced Tumors: An Eastern Cooperative Oncology Group Study (PX990) and Review of IL-1-Based Studies of Hematopoietic Reconstitution.
- Dutcher JP, Neuberg D, Atkins MB, Tester WJ, Wadler S, Stewart JA, Chachoua A, Schuchter LM.Author information 1 Department of Oncology, Montefiore Medical Center , Bronx, New York.AbstractInterleukin-1 (IL-1) is a cytokine critical to inflammation, immunological activation, response to infection, and bone marrow hematopoiesis. Cyclophosphamide downmodulates immune suppressor cells and is cytotoxic to a variety of tumors. A phase I trial of IL-1 and cyclophosphamide was conducted by the Eastern Cooperative Oncology Group. This study evaluated 3 dose levels and 3 schedules in patients with solid tumors. The goal was to evaluate the hematopoietic supportive care effect and possible antitumor effect. Toxicity was fever, chills, hypotension, nausea/emesis, hepatic, and neutropenia. Toxicity increased with dose increases of interleukin-1. Treatment at all dose levels resulted in significant increases in total white blood cell (WBC) counts above baseline. Nadir WBC and nadir absolute neutrophil counts were not significantly different by dose level of IL-1 or schedule of IL-1. Toxicity due to IL-1 at higher doses prohibited further evaluation of this agent for hematopoietic support, particularly in view of the activity and tolerability of more lineage-specific hematopoietic cytokines. Therapeutic interventions in the role of IL-1 in inflammatory conditions and cancer may be further informed by our definition of its clinical and biological effects in this evaluation of dose and schedule.
- Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.J Interferon Cytokine Res.2014 Jan 16. [Epub ahead of print]
- Interleukin-1 (IL-1) is a cytokine critical to inflammation, immunological activation, response to infection, and bone marrow hematopoiesis. Cyclophosphamide downmodulates immune suppressor cells and is cytotoxic to a variety of tumors. A phase I trial of IL-1 and cyclophosphamide was conducted by t
- PMID 24433038
Japanese Journal
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- 東京女子医科大学雑誌 85(E1), E54-E58, 2015-03-31
- 【症例】69歳男性。7年前に十二指腸乳頭部癌に対し、幽門輪温存膵頭十二指腸切除術(child法)を施行した既往歴あり。発熱・悪寒を認め前医受診、Disseminated Intravascular Coagulation(DIC)の診断にて当院に救急搬送となる。来院時、炎症反応高値(WBC21960, CRP24.74)、またCTにて肝膿瘍を認め、血液培養からもグラム陰性桿菌が検出され、細菌性肝膿 …
- NAID 110009888982
- 結腸癌浸潤が原因の脾膿瘍の破裂から汎発性腹膜炎をきたした1例
- 水野 克彦,高橋 滋,安井 寛
- 日本腹部救急医学会雑誌 35(1), 125-129, 2015
- 症例は71歳女性,悪寒・嘔吐・発熱を認め,当院救急外来を受診した。腹部造影CTで脾彎曲部の結腸の壁肥厚を認めた。脾臓に結腸から連続する不明瞭な腫瘤像を認め,結腸癌による脾臓浸潤・脾膿瘍を疑い入院となった。入院後,抗菌薬・輸液で感染制御,精査後に手術方針となったが,入院48時間後に血圧低下を認めた。腹部単純CTで脾膿瘍の穿通,腹腔内穿破,汎発性腹膜炎を疑い緊急手術を施行した。開腹時,膿性腹水を認め, …
- NAID 130005069705
Related Links
- Chills or rigor is a shaking occurring during a high fever. It occurs because cytokines and prostaglandins are released as part of ... the set point for body temperature in the hypothalamus. "Rigor" is sometimes considered a synonym for "chills".
- A feeling you may get down your spine when you have an intense emotinal reaction to a song. This happens when you hear a dramatic climax in music. ...
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★リンクテーブル★
[★]
- 英
- chill、rigor、ague、algid, chills, rigors
- 関
- 硬直、冷やす、冷却、厳密さ、苦しさ、さむけ
[★]
- 冷え、冷気。悪寒、寒気
- 冷淡さ、ひややかさ、興ざまし。おじけ、失意
- ひやりとする。冷える。寒い、凍える。寒さに震えている。
- 関
- ague、algid、cool、cooling、rigor