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Fujimoto M1.
International journal of antimicrobial agents.Int J Antimicrob Agents.2001 Nov;18(5):489-94.
To investigate the effects of gastrectomy on the absorption of drugs, the blood concentrations of the active moieties, cefcapene (CCAP) and ceftizoxime (CTIZ), were determined in 36 gastrectomized patients after oral administration of cefcapene pivoxil (CCAP-PI) and AS-924, prodrug type cephem antib
PMID 11711266

Kasai M1, Hatano S, Kitagawa M, Yoshimi A, Shirahase H, Nishimura K, Kakeya N.
The Journal of antibiotics.J Antibiot (Tokyo).1999 May;52(5):491-500.
To improve the oral absorption of ceftizoxime (CZX), 7beta-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]- 3-cephem-4- carboxylic acid, we synthesized and evaluated a novel series of bifunctional prodrugs, in which L-alanine was introduced into the aminothiazole-oxime moiety at the C-7 positi
PMID 10480574

KASAI Masayasu,HATANO Satoru,KITAGAWA Meiko,YOSHIMI Akihisa,SHIRAHASE Hiroaki,NISHIMURA Ken- Ichi,KAKEYA Nobuharu
Journal of antibiotics 52(5), 491-500, 1999-05-25
… To improve the oral absorption of ceftizoxime (CZX), 7β-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-cephem-4-carboxylic acid, we synthesized and evaluated a novel series of bifunctional prodrugs, in which L-alanine was introduced into the aminothiazole-oxime moiety at the C-7 position of the various lipophilic esters of CZX. …
NAID 10005887008