セフカペン
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- cefcapene pivoxil hydrochloride
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/01/24 06:06:39」(JST)
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Cefcapene
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Systematic (IUPAC) name |
(6R,7R)-3-{[(Aminocarbonyl)oxy]methyl}-7-{(Z)-[2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino}-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid |
Clinical data |
AHFS/Drugs.com |
International Drug Names |
Pregnancy cat. |
? |
Legal status |
℞ Prescription only |
Routes |
Oral |
Identifiers |
CAS number |
135889-00-8 Y |
ATC code |
J01DD17 |
PubChem |
CID 6436055 |
ChemSpider |
4940731 N |
UNII |
4D5D3422MW Y |
KEGG |
D07638 Y |
Chemical data |
Formula |
C17H19N5O6S2 |
Mol. mass |
453.49 g/mol |
SMILES
- O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)C(=C/CC)\c3nc(sc3)N)COC(=O)N)C(=O)O
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InChI
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InChI=1S/C17H19N5O6S2/c1-2-3-8(9-6-30-16(18)20-9)12(23)21-10-13(24)22-11(15(25)26)7(4-28-17(19)27)5-29-14(10)22/h3,6,10,14H,2,4-5H2,1H3,(H2,18,20)(H2,19,27)(H,21,23)(H,25,26)/b8-3-/t10-,14-/m1/s1 N
Key:HJJRIJDTIPFROI-NVKITGPLSA-N N
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N (what is this?) (verify)
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Cefcapene (INN) is a third-generation cephalosporin antibiotic.
Antibacterials: cell envelope antibiotics (J01C-J01D)
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Intracellular |
- inhibit peptidoglycan subunit synthesis and transport: NAM synthesis inhibition (Fosfomycin)
- DADAL/AR inhibitors (Cycloserine)
- bactoprenol inhibitors (Bacitracin)
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Glycopeptide |
- inhibit PG chain elongation: Vancomycin# (Oritavancin
- Telavancin)
- Teicoplanin (Dalbavancin)
- Ramoplanin
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β-lactams/
(inhibit PBP
cross-links) |
Penicillins
(penams)
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Extended sp.
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- aminopenicillins: Amoxicillin#
- Ampicillin# (Pivampicillin
- Hetacillin
- Bacampicillin
- Metampicillin
- Talampicillin)
- Epicillin
- carboxypenicillins: Carbenicillin (Carindacillin)
- Ticarcillin
- Temocillin
- ureidopenicillins: Azlocillin
- Piperacillin
- Mezlocillin
- other: Mecillinam (Pivmecillinam)
- Sulbenicillin
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Narrow sp.
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β-lactamase sensitive
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- Benzylpenicillin (G)#: Clometocillin
- Benzathine benzylpenicillin#
- Procaine benzylpenicillin#
- Azidocillin
- Penamecillin
- Phenoxymethylpenicillin (V)#: Propicillin
- Benzathine phenoxymethylpenicillin
- Pheneticillin
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β-lactamase resistant
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- Cloxacillin# (Dicloxacillin
- Flucloxacillin)
- Oxacillin
- Meticillin
- Nafcillin
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Penems
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Carbapenems
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- Biapenem
- Ertapenem
- antipseudomonal (Doripenem
- Imipenem
- Meropenem)
- Panipenem
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Cephalosporins/Cephamycins
(cephems)
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1st (PEcK)
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- Cefazolin#
- Cefacetrile
- Cefadroxil
- Cefalexin
- Cefaloglycin
- Cefalonium
- Cefaloridine
- Cefalotin
- Cefapirin
- Cefatrizine
- Cefazedone
- Cefazaflur
- Cefradine
- Cefroxadine
- Ceftezole
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2nd (HEN)
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- Cefaclor
- Cefamandole
- Cefminox
- Cefonicid
- Ceforanide
- Cefotiam
- Cefprozil
- Cefbuperazone
- Cefuroxime
- Cefuzonam
- cephamycin (Cefoxitin
- Cefotetan
- Cefmetazole)
- carbacephem (Loracarbef)
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3rd
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- Cefixime#
- Ceftriaxone#
- antipseudomonal (Ceftazidime#
- Cefoperazone)
- Cefcapene
- Cefdaloxime
- Cefdinir
- Cefditoren
- Cefetamet
- Cefmenoxime
- Cefodizime
- Cefotaxime
- Cefpimizole
- Cefpiramide
- Cefpodoxime
- Cefsulodin
- Cefteram
- Ceftibuten
- Ceftiolene
- Ceftizoxime
- oxacephem (Flomoxef
- Latamoxef ‡)
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4th (antips-)
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- Cefepime
- Cefozopran
- Cefpirome
- Cefquinome
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5th
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- Ceftobiprole
- Ceftaroline fosamil
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Veterinary
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- Ceftiofur
- Cefquinome
- Cefovecin
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Monobactams
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- Aztreonam
- Tigemonam
- Carumonam
- Nocardicin A
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β-lactamase inh.
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- penam (Sulbactam
- Tazobactam)
- clavam (Clavulanic acid)
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Combinations
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- Amoxicillin/clavulanic acid#
- Imipenem/cilastatin#
- Ampicillin/flucloxacillin
- Ampicillin/sulbactam (Sultamicillin)
- Piperacillin/tazobactam
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Other |
- polymyxins/detergent (Colistin
- Polymyxin B)
- depolarizing (Daptomycin)
- hydrolyze NAM-NAG (Lysozyme)
- Gramicidin
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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gr+f/gr+a (t)/gr-p (c)/gr-o
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drug (J1p, w, n, m, vacc)
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UpToDate Contents
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English Journal
- [Sensitivity surveillance of Streptococcus pneumoniae isolates for several antibacterial agents in Gifu and Aichi prefecture (2008-2009)].
- Furuya Y, Fukuda Y, Nomura N, Mitsuyama J, Yamaoka K, Asano Y, Sawamura H, Suematsu H, Teraji M, Kawahara Y, Matsukawa Y, Matsubara S, Miyabe T, Arai T, Watanabe K, Mikamo H; Research Laboratories; Toyama Chemical Co., Ltd; Working Group of Tokai Anti-biogram Study Group.SourceResearch Laboratories, Toyama Chemical Co., Ltd.
- The Japanese journal of antibiotics.Jpn J Antibiot.2012 Feb;65(1):1-14.
- We investigated the susceptibility to antibacterials, genotype of penicillin-binding protein (PBP) genes and macrolide resistant genes, and the serotypes against 377 strains of Streptococcus pneumoniae isolated from medical facilities in Gifu and Aichi prefectures between June 2008 and April 2009. T
- PMID 22808690
- Prevention of infectious complication and its risk factors after urological procedures of the upper urinary tract.
- Matsumoto M, Shigemura K, Yamamichi F, Tanaka K, Nakano Y, Arakawa S, Fujisawa M.SourceDepartment of Surgery, Division of Urology, Kobe University Graduate School of Medicine, Kobe, Japan.
- Urologia internationalis.Urol Int.2012;88(1):43-7. Epub 2011 Oct 18.
- BACKGROUND: Invasive upper urinary tract procedures such as retrograde pyelography (RP) or single (S-J) or double J (D-J) stenting are commonly performed to assess or treat ureteral strictures. Urinary tract infection (UTI) can result after such procedures, and prophylactic antimicrobial administrat
- PMID 22005053
Japanese Journal
- A CASE OF WOUND DUAL INFECTION WITH PASTEURELLA DAGMATIS AND PASTEURELLA CANIS RESULTING FROM A DOG BITE - LIMITATIONS OF VITEK-2 SYSTEM IN EXACT IDENTIFICATION OF PASTEURELLA SPECIES
- Akahane T,Nagata M,Matsumoto T,Murayama N,Isaka A,Kameda T,Fujita M,Oana K,Kawakami Y
- EUROPEAN JOURNAL OF MEDICAL RESEARCH 16(12), 531-536, 2011-12-02
- … Both the isolates were highly susceptible to many antibiotics and the patient was successfully treated with the administration of so-called the first generation cephalosporin, cefazolin followed by so-called the third generation cephalosporin, cefcapene pivoxil. …
- NAID 120005199151
- Evaluation of short-term clinical efficacy of 3-day therapy with azithromycin in comparison with 5-day cefcapene-pivoxyl for acute streptococcal tonsillopharyngitis in primary care
- KOGA Takeharu,RIKIMARU Toru,TOKUNAGA Naoto,HIGASHI Toshihiro,NAKAMURA Masahiro,ICHIKAWA Yoichiro,MATSUO Kazuhiko
- Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 17(4), 499-503, 2011-08-01
- NAID 10029523665
- 伊藤 香世子,日野 頼真,千葉 由幸 [他],相原 道子,池澤 善郎,堀内 義仁
- Journal of environmental dermatology and cutaneous allergology = / the Japanese Society for Dermatoallergology and Contact Dermatitis 5(1), 36-38, 2011-01-31
- NAID 10027902336
Related Links
- Cefcapene Pivoxil [CFPN-PI] セフカペン ピボキシル, セフェム系(セファロスポリン系) 1. 商品名 先発品 フロモックス小児用細粒100mg 【塩野義製薬】 フロモックス錠75mg/フロモックス錠100mg 【塩野義製薬】 後発品 後発品15件 ...
- Cefcapene is a medicine available in a number of countries worldwide. A list of US medications equivalent to Cefcapene is available on the Drugs.com website. ... Drugs.com provides accurate and independent information on more ...
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