頚動脈硬化性疾患、頸動脈硬化性疾患
- 関
- carotid arterial disease、carotid artery disease、carotid atherosclerosis、internal carotid artery disease
WordNet
- an impairment of health or a condition of abnormal functioning
- caused by or altered by or manifesting disease or pathology; "diseased tonsils"; "a morbid growth"; "pathologic tissue"; "pathological bodily processes" (同)morbid, pathologic, pathological
- of or relating to either of the two major arteries supplying blood to the head and neck
- of or relating to atherosclerosis
PrepTutorEJDIC
- (体の)『病気』,疾患 / (精神・道徳などの)病気,病弊
- 女性の話術芸人 =diseur
- 病気にかかった / 病的な,不健全な(morbid)
- 頚(けい)動脈 / 頚動脈の
UpToDate Contents
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English Journal
- Pathophysiology of superficial femoral artery in-stent restenosis.
- Yahagi K1, Otsuka F, Sakakura K, Sanchez OD, Kutys R, Ladich E, Kolodgie FD, Virmani R, Joner M.Author information 1CVPath Institute, Inc., Gaithersburg, MD, USA - mjoner@cvpath.org.AbstractPeripheral artery disease (PAD) is an emerging problem especially with aging population and increase in the incidence of diabetes and metabolic syndrome. The disease is histologically characterized by the presence of moderate to severe calcification and fibrous plaques as compared to coronary and carotid atherosclerotic disease, which are richer in necrotic core. Endovascular therapy for the superficial femoral artery (SFA), at least in the United States, has been largely limited to balloon angioplasty and stenting and these are considered safe and relatively effective therapies. However, the patency rates remain low even at one year and restenosis is a growing and challenging problem. Recently the development of newer devices, i.e., drug-eluting stent, and drug coated balloon are showing greater efficacy and are being adopted into daily practice. In this review, we will present the morphologic characteristics of the underlying SFA atherosclerotic disease and discuss in-stent restenosis and the mechanisms that may be involved in the induction of excessive smooth muscle cell proliferation and deposition of proteoglycans and collagen, that lead to restenosis.
- The Journal of cardiovascular surgery.J Cardiovasc Surg (Torino).2014 Jun;55(3):307-23.
- Peripheral artery disease (PAD) is an emerging problem especially with aging population and increase in the incidence of diabetes and metabolic syndrome. The disease is histologically characterized by the presence of moderate to severe calcification and fibrous plaques as compared to coronary and ca
- PMID 24755699
- KCC2 expression changes in Diazepam-treated neonatal rats with hypoxia-ischaemia brain damage.
- Ma JY1, Zhang SP2, Guo LB1, Li YM1, Li Q3, Wang SQ1, Liu HM1, Wang C4.Author information 1School of Pharmaceutical Science, Zhengzhou University, Ke Xue Da Dao 100, Zhengzhou 450001, PR China.2Medical College of Kaifeng University, Kaifeng 475001, PR China.3The First Affiliated Hospital of Henan College of Traditional Chinese Medicine, Zhengzhou 450000, PR China; Key Laboratory of Viral Diseases Prevention and Treatment of Traditional Chinese Medicine of Henan Province, Zhengzhou 450000, PR China.4School of Pharmaceutical Science, Zhengzhou University, Ke Xue Da Dao 100, Zhengzhou 450001, PR China. Electronic address: wangcong@zzu.edu.cn.AbstractHypoxia-ischaemia brain damage (HIBD) is a major type of perinatal brain injury in newborns. In this study, we investigate the short- and long-term neuroprotective effects of Diazepam on neonatal rats with HIBD and the potential mechanisms underlying its protective effects. Seven-day-old Sprague-Dawley rats were subjected to left carotid artery ligation followed by a 2-h exposure to 8% oxygen and 92% nitrogen. Diazepam was administered immediately via intraperitoneal (i.p.) injection after inducing HIBD at a dose of 10mgkg(-1)8h(-1) for three consecutive days. Three days after HIBD, rats were decapitated, and the extent of brain injury was evaluated using 2,3,5-triphenyltetrazolium chloride (TTC) staining. Additionally, the expression of Potassium-chloride cotransporter-2 (KCC2) was analysed using real-time PCR, Western blot analysis and immunohistochemistry. Three weeks after HIBD, rats were subjected to the Morris water maze (MWM) test and the locomotor activity test to determine the long-term therapeutic effects of Diazepam. We observed that the volume of infarction in the Diazepam group was significantly less (P<0.01) compared with the HIBD group. We also observed that the learning and memory abilities of the Diazepam rats improved significantly compared with the untreated rats (P<0.05) and that the decrease in KCC2 expression was prevented (P<0.01). Early treatment with Diazepam appears to attenuate HIBD and can efficiently improve the long-term learning and memory capabilities of the animal. A potential mechanism underlying these effects may involve preventing the decrease in KCC2 expression.
- Brain research.Brain Res.2014 May 14;1563:22-30. doi: 10.1016/j.brainres.2014.03.034. Epub 2014 Apr 4.
- Hypoxia-ischaemia brain damage (HIBD) is a major type of perinatal brain injury in newborns. In this study, we investigate the short- and long-term neuroprotective effects of Diazepam on neonatal rats with HIBD and the potential mechanisms underlying its protective effects. Seven-day-old Sprague-Daw
- PMID 24709118
- Impact of diabetes mellitus on characteristics of carotid plaques and outcomes after carotid endarterectomy.
- Mizuhashi S1, Kataoka H, Sano N, Ideguchi M, Higashi M, Miyamoto Y, Iihara K.Author information 1Department of Neurosurgery, National Cerebral and Cardiovascular Center, Suita, Japan.AbstractBACKGROUND: Published results for carotid endarterectomy (CEA) in symptomatic and asymptomatic severe carotid stenosis with diabetes mellitus (DM) are contradictory. To evaluate perioperative and long-term results of CEA in patients with DM, we retrospectively analyzed data of patients with or without DM who underwent CEA in our institute.
- Acta neurochirurgica.Acta Neurochir (Wien).2014 May;156(5):927-33. doi: 10.1007/s00701-014-2040-x. Epub 2014 Mar 15.
- BACKGROUND: Published results for carotid endarterectomy (CEA) in symptomatic and asymptomatic severe carotid stenosis with diabetes mellitus (DM) are contradictory. To evaluate perioperative and long-term results of CEA in patients with DM, we retrospectively analyzed data of patients with or witho
- PMID 24633985
Japanese Journal
- 放射線誘発性頸動脈狭窄症に対する頸動脈ステント留置術（CAS）後にplaque protrusion を繰り返し治療に難渋した1 症例
- Involvement of Angiotensin II Type 1 and 2 Receptors in Gelatinase Regulation in Human Carotid Atheroma in vitro
- Rationale and Design of the PROSPECTIVE Trial: Probucol Trial for Secondary Prevention of Atherosclerotic Events in Patients with Prior Coronary Heart Disease
Related Links
- Atherosclerosis is a degenerative disease of the arteries resulting in plaques consisting of necrotic cells, lipids, and cholesterol crystals (see the images below). These plaques can result in symptoms by causing ...
- The locations most frequently affected by carotid atherosclerosis are the proximal internal carotid artery (ie, the origin) and the common carotid artery bifurcation. Progression of atheromatous plaque at the carotid bifurcation results in ...
★リンクテーブル★
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- 関
- carotid arterial disease、carotid atherosclerosis、carotid atherosclerotic disease、internal carotid artery disease
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- 関
- carotid artery disease、carotid atherosclerosis、carotid atherosclerotic disease、internal carotid artery disease
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- 関
- carotid arterial disease、carotid artery disease、carotid atherosclerosis、carotid atherosclerotic disease
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- 英
- carotid atherosclerotic disease
- 関
- 頚動脈狭窄症、頚動脈疾患、頸動脈疾患、内頸動脈疾患、頚動脈硬化性疾患
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- 英
- carotid atherosclerotic disease
- 関
- 頸動脈硬化性疾患
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- 疾患：illnessより厳密な概念。「ある臓器に明確な障害が確認され、それによって症状が出ているとはっきり説明できる場合」 (PSY.9)
- 特定の原因、病態生理、症状、経過、予後、病理組織所見が全てそろった場合 (PSY.9)
- something that is very wrong with people's attitudes, way of life or with society.
- 関
- ail、ailment、disease entity、disorder、ill、illness、malady、sick、sickness
- disease ≠ illness ≠ disorder
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- アテローム硬化性の、アテローム硬化型の、粥状硬化の
- 関
- atherosclerosis
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- 関
- carotid artery