カルシウム・カルモジュリン依存性プロテインキナーゼキナーゼ
WordNet
- relying on or requiring a person or thing for support, supply, or what is needed; "dependent children"; "dependent on moisture"
- addicted to a drug (同)dependant, drug-addicted, hooked, strung-out
- contingent on something else (同)dependant, qualified
- (of a clause) unable to stand alone syntactically as a complete sentence; "a subordinate (or dependent) clause functions as a noun or adjective or adverb within a sentence" (同)subordinate
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- a white metallic element that burns with a brilliant light; the fifth most abundant element in the earths crust; an important component of most plants and animals (同)Ca, atomic number 20
- an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
- the basic unit of money in Papua New Guinea
PrepTutorEJDIC
- 『頼っている』,依存している,従属している / 扶養される人(家族)
- 蛋白(たんばく)質
- 『カルシウム』(金属元素;化学記号は『Ca』)
UpToDate Contents
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English Journal
- Calcium homeostasis and protein kinase/phosphatase balance participate in nicotine-induced memory improvement in passive avoidance task in mice.
- Michalak A1, Biala G2.
- Behavioural brain research.Behav Brain Res.2017 Jan 15;317:27-36. doi: 10.1016/j.bbr.2016.09.023. Epub 2016 Sep 12.
- Long-term potentiation (LTP) and long-term depression (LTD) depend on specific postsynaptic Ca2+/calmodulin concentration. LTP results from Ca2+ influx through the activated NMDA receptors or voltage-gated calcium channels (VGCCs) and is linked with activation of protein kinases including mitogen-ac
- PMID 27633557
- Differential Roles for L-Type Calcium Channel Subtypes in Alcohol Dependence.
- Uhrig S1, Vandael D2, Marcantoni A2, Dedic N3, Bilbao A1, Vogt MA4, Hirth N1, Broccoli L1, Bernardi RE1, Schönig K5, Gass P4, Bartsch D5, Spanagel R1, Deussing JM3, Sommer WH1,6, Carbone E2, Hansson AC1.
- Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.Neuropsychopharmacology.2017 Jan 4. doi: 10.1038/npp.2016.266. [Epub ahead of print]
- It has previously been shown that the inhibition of L-type calcium channels (LTCCs) decreases alcohol consumption, although the contribution of the central LTCC subtypes Cav1.2 and Cav1.3 remains unknown. Here, we determined changes in Cav1.2 (Cacna1c) and Cav1.3 (Cacna1d) mRNA and protein expressio
- PMID 27905406
- Combined Memantine and Donepezil Treatment Improves Behavioral and Psychological Symptoms of Dementia-Like Behaviors in Olfactory Bulbectomized Mice.
- Yabuki Y1, Matsuo K, Hirano K, Shinoda Y, Moriguchi S, Fukunaga K.
- Pharmacology.Pharmacology.2017 Jan 4;99(3-4):160-171. doi: 10.1159/000452839. [Epub ahead of print]
- Memantine, an uncompetitive N-methyl-D-aspartate receptor antagonist, and the cholinesterase inhibitor, donepezil, are approved in most countries for treating moderate-to-severe Alzheimer's disease (AD). These drugs have different molecular targets; thus, it is expected that the effects of combined
- PMID 28049192
Japanese Journal
- Regulatory Effect of Bee Venom on Methamphetamine-Induced Cellular Activities in Prefrontal Cortex and Nucleus Accumbens in Mice
- , ,
- Biological and Pharmaceutical Bulletin 38(1), 48-52, 2015
- … To expand on our observations, the present study was designed to determine the suppressive mechanisms of BV acupuncture in the development of METH-induced CPP by evaluating the changes in expression of ΔFosB, phosphorylated extracellular signal-regulated kinase 1/2 (pERK), and phosphorylated calcium/calmodulin-dependent protein kinase type II (pCaMKII) in the prefrontal cortex (PFC) and nucleus accumbens (NAc) in mice. …
- NAID 130004872229
- Cardiac-Specific Inhibition of Kinase Activity in Calcium/Calmodulin-Dependent Protein Kinase Kinase-β Leads to Accelerated Left Ventricular Remodeling and Heart Failure after Transverse Aortic Constriction in Mice
- Watanabe Shin,Horie Takahiro,Nagao Kazuya,Kuwabara Yasuhide,Baba Osamu,Nishi Hitoo,Sowa Naoya,Narazaki Michiko,Matsuda Tetsuya,Takemura Genzou,Wada Hiromichi,Hasegawa Koji,Kimura Takeshi,Ono Koh
- PLoS ONE 9(9), 2014-09-25
- … [Methods and Results]We generated cardiac-specific kinase-dead (kd) calcium/calmodulin-dependent protein kinase kinase-β (CaMKKβ) transgenic (α-MHC CaMKKβ[kd] TG) mice using α-myosin heavy chain (α-MHC) promoter. …
- NAID 120005496630
- Roles of Calcium/Calmodulin-Dependent Kinase II in Long-Term Memory Formation in Crickets
- Mizunami Makoto,Nemoto Yuko,Terao Kanta,Hamanaka Yoshitaka,Matsumoto Yukihisa
- PLoS ONE 9(9), e107442, 2014-09-12
- … Ca2+/calmodulin (CaM)-dependent protein kinase II (CaMKII) is a key molecule in many systems of learning and memory in vertebrates, but roles of CaMKII in invertebrates have not been characterized in detail. … Crickets subjected to 3-trial conditioning to associate an odor with reward exhibited memory that lasts for a few days, which is characterized as protein synthesis-dependent LTM. …
- NAID 120005496509
Related Links
- The sensitivity of the CaMKII enzyme to calcium and calmodulin is governed by the variable and self-associative domains. This sensitivity level of CaMKII will also ...
- Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium- triggered signaling cascade involved in a number of cellular processes. Isoform 1 , isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 ...
★リンクテーブル★
[★]
- 英
- calcium-calmodulin-dependent protein kinase kinase
[★]
- 関
- depend、dependence、dependency、dependently
[★]
キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase
[★]
プロテインキナーゼ
- 同
- protein kinases
[★]
[★]
カルモジュリン CaM